Development of the small-molecule antiviral ST-246®as a smallpox therapeutic

Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo

(2010) A. W. Rimoin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of ST-246® on ACAM2000™ smallpox vaccine reactogenicity, immunogenicity, and protective efficacy in immunodeficient mice

(2010) Aklile Berhanu et al.   VACCINE

Development of ST-246® for Treatment of Poxvirus Infections

(2010) Robert Jordan et al.   Viruses-Basel

ST-246 Inhibits In Vivo Poxvirus Dissemination, Virus Shedding, and Systemic Disease Manifestation

(2009) A. Berhanu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

ST-246 Antiviral Efficacy in a Nonhuman Primate Monkeypox Model: Determination of the Minimal Effective Dose and Human Dose Justification

(2009) R. Jordan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nonhuman Primates Are Protected from Smallpox Virus or Monkeypox Virus Challenges by the Antiviral Drug ST-246

(2009) J. Huggins et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cowpox virus infection: an emerging health threat

(2009) Rengina M Vorou et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice

(2009) D. W. Grosenbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccinia virus p37 interacts with host proteins associated with LE-derived transport vesicle biogenesis

(2009) Yali Chen et al.   Virology Journal

Single-Dose Safety and Pharmacokinetics of ST-246, a Novel Orthopoxvirus Egress Inhibitor

(2008) R. Jordan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit model

(2008) Aysegul Nalca et al.   ANTIVIRAL RESEARCH

US Civilian Smallpox Preparedness and Response Program, 2003

(2008) Raymond A. Strikas et al.   CLINICAL INFECTIOUS DISEASES

Severe Eczema Vaccinatum in a Household Contact of a Smallpox Vaccinee

(2008) Surabhi Vora et al.   CLINICAL INFECTIOUS DISEASES

Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination

(2008) Douglas W. Grosenbach et al.   VACCINE

Clonal vaccinia virus grown in cell culture fully protects monkeys from lethal monkeypox challenge

(2007) Kathleen A. Marriott et al.   VACCINE