How to manage asparaginase hypersensitivity in acute lymphoblastic leukemia

A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia

(2014) Wing H. Tong et al.   BLOOD

Safety profile of asparaginaseErwinia chrysanthemiin a large compassionate-use trial

(2014) Paul V. Plourde et al.   PEDIATRIC BLOOD & CANCER

Erwinia asparaginase achieves therapeutic activity after pegaspargase allergy: a report from the Children's Oncology Group

(2013) W. L. Salzer et al.   BLOOD

Postinduction Dexamethasone and Individualized Dosing ofEscherichia ColiL-Asparaginase Each Improve Outcome of Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia: Results From a Randomized Study—Dana-Farber Cancer Institute ALL Consortium Protocol 00-01

(2013) Lynda M. Vrooman et al.   JOURNAL OF CLINICAL ONCOLOGY

Comparison of Hypersensitivity Reactions to PEG-Asparaginase in Children After Intravenous and Intramuscular Administration

(2013) Keith J. August et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Managing Hypersensitivity to Asparaginase in Pediatrics, Adolescents, and Young Adults

(2013) Sara E. Shinnick et al.   Journal of Pediatric Oncology Nursing

Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia

(2012) C Liu et al.   LEUKEMIA

Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia

(2012) Stephen P. Hunger et al.   PEDIATRIC BLOOD & CANCER

Anti-Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated E coli asparaginase: a retrospective analysis within the ALL-BFM trials

(2011) A. Willer et al.   BLOOD

Polyethylene Glycol-conjugated L-asparaginase Versus Native L-asparaginase in Combination With Standard Agents for Children With Acute Lymphoblastic Leukemia in Second Bone Marrow Relapse

(2011) Joanne Kurtzberg et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Prevention and management of asparaginase/pegasparaginase-associated toxicities in adults and older adolescents: recommendations of an expert panel

(2011) Wendy Stock et al.   LEUKEMIA & LYMPHOMA

Comparison of allergic reactions to pegasparaginase given intravenously versus intramuscularly

(2011) Mahati Pidaparti et al.   PEDIATRIC BLOOD & CANCER

Expanding Targets for a Metabolic Therapy of Cancer: L-Asparaginase

(2011) Daniele Covini et al.   Recent Patents on Anti-Cancer Drug Discovery

L-asparaginase treatment in acute lymphoblastic leukemia

(2010) Rob Pieters et al.   CANCER

Genetic Variations in GRIA1 on Chromosome 5q33 Related to Asparaginase Hypersensitivity

(2010) S-H Chen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Tolerability and Efficacy of L-Asparaginase Therapy in Pediatric Patients With Acute Lymphoblastic Leukemia

(2010) Elizabeth A. Raetz et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

A Desensitization Protocol in Children With L-Asparaginase Hypersensitivity

(2010) Sinan Akbayram et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

The cross-reactivity of anti-asparaginase antibodies against different l-asparaginase preparations

(2009) Beata Zalewska-Szewczyk et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Comparison of Native E. coli and PEG Asparaginase Pharmacokinetics and Pharmacodynamics in Pediatric Acute Lymphoblastic Leukemia

(2009) J C Panetta et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacokinetics, pharmacodynamics, efficacy, and safety of a new recombinant asparaginase preparation in children with previously untreated acute lymphoblastic leukemia: a randomized phase 2 clinical trial

(2008) R. Pieters et al.   BLOOD

Acute lymphoblastic leukaemia

(2008) Ching-Hon Pui et al.   LANCET