DNA damage response and repair: insights into strategies for radiation sensitization of gliomas

EGFR Mutations and Lung Cancer

(2011) Gilda da Cunha Santos et al.   Annual Review of Pathology-Mechanisms of Disease

EGFR Nuclear Translocation Modulates DNA Repair following Cisplatin and Ionizing Radiation Treatment

(2011) G. Liccardi et al.   CANCER RESEARCH

Mechanism of p53 stabilization by ATM after DNA damage

(2010) Qian Cheng et al.   CELL CYCLE

Radiosensitizing Properties of Bortezomib Depend on Therapeutic Schedule

(2010) Marianne Labussière et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Targeting EGFR Induced Oxidative Stress by PARP1 Inhibition in Glioblastoma Therapy

(2010) Masayuki Nitta et al.   PLoS One

Poly(ADP-Ribose) Polymerase Inhibition as a Model for Synthetic Lethality in Developing Radiation Oncology Targets

(2010) Anthony J. Chalmers et al.   SEMINARS IN RADIATION ONCOLOGY

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

Saddle block analgesia for high-dose-rate brachytherapy: A prospective study

(2009) Hance A. Clarke et al.   Brachytherapy

EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma

(2009) B. Mukherjee et al.   CANCER RESEARCH

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

Targeting the DNA Damage Response in Cancer

(2009) Mats Ljungman   CHEMICAL REVIEWS

In vitro and In vivo Radiosensitization of Glioblastoma Cells by the Poly (ADP-Ribose) Polymerase Inhibitor E7016

(2009) A. L. Russo et al.   CLINICAL CANCER RESEARCH

Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme

(2009) David M. Peereboom et al.   JOURNAL OF NEURO-ONCOLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Cdk1 Participates in BRCA1-Dependent S Phase Checkpoint Control in Response to DNA Damage

(2009) Neil Johnson et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

(2009) Simon Bekker-Jensen et al.   NATURE CELL BIOLOGY

Multiple functions of MRN in end-joining pathways during isotype class switching

(2009) Maria Dinkelmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Erlotinib Attenuates Homologous Recombinational Repair of Chromosomal Breaks in Human Breast Cancer Cells

(2008) L. Li et al.   CANCER RESEARCH

In vitro and In vivo Radiosensitization Induced by the DNA Methylating Agent Temozolomide

(2008) W. J. Kil et al.   CLINICAL CANCER RESEARCH

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

(2008) J Ross Chapman et al.   EMBO REPORTS

Replication-Dependent Radiosensitization of Human Glioma Cells by Inhibition of Poly(ADP-Ribose) Polymerase: Mechanisms and Therapeutic Potential

(2008) Fiona A. Dungey et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Phase I Trial Using Proteasome Inhibitor Bortezomib and Concurrent Temozolomide and Radiotherapy for Central Nervous System Malignancies

(2008) Gregory J. Kubicek et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Phase I/II Trial of Erlotinib and Temozolomide With Radiation Therapy in the Treatment of Newly Diagnosed Glioblastoma Multiforme: North Central Cancer Treatment Group Study N0177

(2008) Paul D. Brown et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

(2008) Michael D. Prados et al.   JOURNAL OF CLINICAL ONCOLOGY

Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin

(2008) Kyunghee Burkitt et al.   Molecular Cancer

HSP90 inhibitor, DMAG, synergizes with radiation of lung cancer cells by interfering with base excision and ATM-mediated DNA repair

(2008) T. T. Koll et al.   MOLECULAR CANCER THERAPEUTICS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE