Oncolytic herpes simplex virus vectors and chemotherapy: are combinatorial strategies more effective for cancer?

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Thalidomide suppressed the growth of 4T1 cells into solid tumors in Balb/c mice in a combination therapy with the oncolytic fusogenic HSV-1 OncdSyn

(2009) Anna Israyelyan et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells

(2009) B J Passer et al.   CANCER GENE THERAPY

Enhanced cytotoxicity with a novel system combining the paclitaxel-2′-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus

(2009) Daisuke Ishida et al.   CANCER LETTERS

Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors

(2009) H. Wakimoto et al.   CANCER RESEARCH

Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer

(2009) Amy R. Nelson et al.   CANCER SCIENCE

The emergence of combinatorial strategies in the development of RNA oncolytic virus therapies

(2009) Thi Lien-Anh Nguyen et al.   CELLULAR MICROBIOLOGY

Pharmacologic and Chemical Adjuvants in Tumor Virotherapy

(2009) Christopher Alvarez-Breckenridge et al.   CHEMICAL REVIEWS

Oncolytic Adenoviral Mutants with E1B19K Gene Deletions Enhance Gemcitabine-induced Apoptosis in Pancreatic Carcinoma Cells and Anti-Tumor Efficacy In vivo

(2009) S. Leitner et al.   CLINICAL CANCER RESEARCH

“Buy One Get One Free”: Armed Viruses for the Treatment of Cancer Cells and their Microenvironment

(2009) Balveen Kaur et al.   CURRENT GENE THERAPY

Malignant pleural mesothelioma

(2009) Rolf A Stahel et al.   Future Oncology

Histone deacetylase inhibitors: Potential in cancer therapy

(2009) P.A. Marks et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phase II Clinical Trial of a Granulocyte-Macrophage Colony-Stimulating Factor–Encoding, Second-Generation Oncolytic Herpesvirus in Patients With Unresectable Metastatic Melanoma

(2009) Neil N. Senzer et al.   JOURNAL OF CLINICAL ONCOLOGY

Engineered herpes simplex viruses efficiently infect and kill CD133+ human glioma xenograft cells that express CD111

(2009) Gregory K. Friedman et al.   JOURNAL OF NEURO-ONCOLOGY

Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells

(2009) Shizuko Sei et al.   Molecular Cancer

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Neuroblastoma Cell Lines Contain Pluripotent Tumor Initiating Cells That Are Susceptible to a Targeted Oncolytic Virus

(2009) Yonatan Y. Mahller et al.   PLoS One

Therapeutic Implications of the Cancer Stem Cell Hypothesis

(2009) Maximilian Diehn et al.   SEMINARS IN RADIATION ONCOLOGY

Increased apoptosis and reduced replication efficiency of the E3 region-modified dl309 adenovirus in cancer cells

(2009) Merilyn H. Hibma et al.   VIRUS RESEARCH

Thalidomide for treatment of multiple myeloma: 10 years later

(2008) A. Palumbo et al.   BLOOD

Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy

(2008) Jennifer S. Carew et al.   CANCER LETTERS

Cancer Cell Death Enhances the Penetration and Efficacy of Oncolytic Herpes Simplex Virus in Tumors

(2008) S. Nagano et al.   CANCER RESEARCH

Synergy of a Herpes Oncolytic Virus and Paclitaxel for Anaplastic Thyroid Cancer

(2008) S.-F. Lin et al.   CLINICAL CANCER RESEARCH

Small interfering RNA therapy in cancer: mechanism, potential targets, and clinical applications

(2008) Chuan Huang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Efficacy and Safety of the Oncolytic Herpes Simplex Virus rRp450 Alone and Combined With Cyclophosphamide

(2008) Mark A Currier et al.   MOLECULAR THERAPY

Therapeutic Efficacy of a Herpes Simplex Virus With Radiation or Temozolomide for Intracranial Glioblastoma After Convection-enhanced Delivery

(2008) Costas G Hadjipanayis et al.   MOLECULAR THERAPY

Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses

(2008) Akihiro Otsuki et al.   MOLECULAR THERAPY

Trichostatin A and Oncolytic HSV Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects

(2008) Ta-Chiang Liu et al.   MOLECULAR THERAPY

A Herpes Oncolytic Virus Can Be Delivered Via the Vasculature to Produce Biologic Changes in Human Colorectal Cancer

(2008) Yuman Fong et al.   MOLECULAR THERAPY

Phase Ib Trial of Mutant Herpes Simplex Virus G207 Inoculated Pre-and Post-tumor Resection for Recurrent GBM

(2008) James M Markert et al.   MOLECULAR THERAPY

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

(2008) T. L.-A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice

(2008) Anna Israyelyan et al.   Virology Journal