Role of prolonged mitotic checkpoint activation in the formation and treatment of cancer

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Chromosomal instability determines taxane response

(2009) C. Swanton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Cell Type Variation in Responses to Antimitotic Drugs that Target Microtubules and Kinesin-5

(2008) J. Shi et al.   CANCER RESEARCH

A B-Myb complex containing clathrin and filamin is required for mitotic spindle function

(2008) Tomohiro Yamauchi et al.   EMBO JOURNAL

Therapy-related myelodysplasia and acute myeloid leukemia following paclitaxel- and carboplatin-based chemotherapy in an ovarian cancer patient: a case report and literature review

(2008) S. YEASMIN et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Examining the link between chromosomal instability and aneuploidy in human cells

(2008) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome

(2008) Karyn M. Austin et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Papillomavirus E7 Protein Deregulates Mitosis via an Association with Nuclear Mitotic Apparatus Protein 1

(2008) C. L. Nguyen et al.   JOURNAL OF VIROLOGY

Extra centrosomes and/or chromosomes prolong mitosis in human cells

(2008) Zhenye Yang et al.   NATURE CELL BIOLOGY

A Role for Polyploidy in the Tumorigenicity of Pim-1-Expressing Human Prostate and Mammary Epithelial Cells

(2008) Meejeon Roh et al.   PLoS One

Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo

(2008) E. Diaz-Rodriguez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer

(2008) M. Perez-Moreno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA