Molecular pathology of mixed-lineage leukemia

The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group

(2009) T. Burmeister et al.   BLOOD

New insights to the MLL recombinome of acute leukemias

(2009) C Meyer et al.   LEUKEMIA

The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia

(2009) S Thoene et al.   LEUKEMIA

Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents

(2009) Cecily A. Bennett et al.   LEUKEMIA RESEARCH

TFIIH and P-TEFb Coordinate Transcription with Capping Enzyme Recruitment at Specific Genes in Fission Yeast

(2009) Laia Viladevall et al.   MOLECULAR CELL

The PHD fingers of MLL block MLL fusion protein-mediated transformation

(2008) A. G. Muntean et al.   BLOOD

Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia

(2008) M. A. Phelps et al.   BLOOD

Farnesyltransferase inhibitors and their potential role in therapy for myelodysplastic syndromes and acute myeloid leukaemia

(2008) Thorsten Braun et al.   BRITISH JOURNAL OF HAEMATOLOGY

Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes

(2008) Akihiko Yokoyama et al.   CANCER CELL

H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

(2008) Andrei V. Krivtsov et al.   CANCER CELL

Loss of MLL PHD Finger 3 Is Necessary for MLL-ENL-Induced Hematopoietic Stem Cell Immortalization

(2008) J. Chen et al.   CANCER RESEARCH

Advances in the Development of Cancer Therapeutics Directed against the RAS-Mitogen-Activated Protein Kinase Pathway

(2008) J. S. Sebolt-Leopold   CLINICAL CANCER RESEARCH

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

(2008) M. G. Guenther et al.   GENES & DEVELOPMENT

WDR5 Interacts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket

(2008) Ji-Joon Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CDK9 a Potential Target for Drug Development

(2008) Fernanda Canduri et al.   Medicinal Chemistry

DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells

(2008) D. J. Steger et al.   MOLECULAR AND CELLULAR BIOLOGY

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy

(2008) Zhong Wang et al.   NATURE

Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2

(2008) C Bach et al.   ONCOGENE

MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression

(2008) F. E. Erfurth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical roles for c-Myb in hematopoietic progenitor cells

(2008) Kylie T. Greig et al.   SEMINARS IN IMMUNOLOGY

The AF4-mimetic peptide, PFWT, induces necrotic cell death in MV4-11 leukemia cells

(2007) Christine M. Palermo et al.   LEUKEMIA RESEARCH