Development of humanized mouse models to study human malaria parasite infection

Macrophages prevent human red blood cell reconstitution in immunodeficient mice

(2011) Z. Hu et al.   BLOOD

Disruption of the Plasmodium falciparum liver-stage antigen-1 locus causes a differentiation defect in late liver-stage parasites

(2011) Sebastian A. Mikolajczak et al.   CELLULAR MICROBIOLOGY

A systematic analysis of the early transcribed membrane protein family throughout the life cycle of Plasmodium yoelii

(2011) Drew C. MacKellar et al.   CELLULAR MICROBIOLOGY

Further Improvements of the P. falciparum Humanized Mouse Model

(2011) Ludovic Arnold et al.   PLoS One

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

(2011) A. Rongvaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung

(2011) T. Willinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

(2011) Nicolas Legrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transgenic expression of human signal regulatory protein alpha in Rag2−/−γc−/−mice improves engraftment of human hematopoietic cells in humanized mice

(2011) Till Strowig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasmodium falciparum PF10_0164 (ETRAMP10.3) Is an Essential Parasitophorous Vacuole and Exported Protein in Blood Stages

(2010) Drew C. MacKellar et al.   EUKARYOTIC CELL

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

(2010) Karl-Dimiter Bissig et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of innate defences against Plasmodium falciparum in immunodeficient mice

(2010) Ludovic Arnold et al.   MALARIA JOURNAL

Malaria Parasite Development in the Mosquito and Infection of the Mammalian Host

(2009) Ahmed S.I. Aly et al.   Annual Review of Microbiology

Improved Murine Model of Malaria Using Plasmodium falciparum Competent Strains and Non-Myelodepleted NOD-scid IL2R null Mice Engrafted with Human Erythrocytes

(2009) M. B. Jimenez-Diaz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Humanized Mice for Modeling Human Infectious Disease: Challenges, Progress, and Outlook

(2009) Nicolas Legrand et al.   Cell Host & Microbe

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

(2009) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design

(2009) K. M. VanBuskirk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-γ/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection

(2009) James F. Cummings et al.   VACCINE

Rescue of Fertility in Homozygous Mice for the Urokinase Plasminogen Activator Transgene by the Transplantation of Mouse Hepatocytes

(2008) Nicolas M. Brezillon et al.   CELL TRANSPLANTATION

Quantitative measurement ofPlasmodium-infected erythrocytes in murine models of malaria by flow cytometry using bidimensional assessment of SYTO-16 fluorescence

(2008) María Belén Jiménez-Díaz et al.   CYTOMETRY PART A

Malaria: progress, perils, and prospects for eradication

(2008) Brian M. Greenwood et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

(2008) Nicholas D. Huntington et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Murine Model of falciparum-Malaria by In Vivo Selection of Competent Strains in Non-Myelodepleted Mice Engrafted with Human Erythrocytes

(2008) Iñigo Angulo-Barturen et al.   PLoS One