Mechanisms of infection by the human fungal pathogenCryptococcus neoformans

App1: An Antiphagocytic Protein That Binds to Complement Receptors 3 and 2

(2014) P. Stano et al.   JOURNAL OF IMMUNOLOGY

Cryptococcus neoformansphospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier

(2012) Ravi Maruvada et al.   CELLULAR MICROBIOLOGY

Antifungal Activity of the Essential Oils of Callitris neocaledonica and C. sulcata Heartwood (Cupressaceae)

(2012) Jean Waikedre et al.   CHEMISTRY & BIODIVERSITY

Difference in Cryptococcus neoformans cellular and capsule size in sequential pulmonary and meningeal infection: a postmortem study

(2012) Steve Xie et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Peroxisomal and Mitochondrial β-Oxidation Pathways Influence the Virulence of the Pathogenic Fungus Cryptococcus neoformans

(2012) Matthias Kretschmer et al.   EUKARYOTIC CELL

Titan Cells Confer Protection from Phagocytosis in Cryptococcus neoformans Infections

(2012) Laura H. Okagaki et al.   EUKARYOTIC CELL

Prostaglandin E2 Suppresses Antifungal Immunity by Inhibiting Interferon Regulatory Factor 4 Function and Interleukin-17 Expression in T Cells

(2012) Patricia A. Valdez et al.   IMMUNITY

Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans

(2012) André Moraes Nicola et al.   INFECTION AND IMMUNITY

Surfactant Protein D Facilitates Cryptococcus neoformans Infection

(2012) Scarlett Geunes-Boyer et al.   INFECTION AND IMMUNITY

Capsule Independent Uptake of the Fungal Pathogen Cryptococcus neoformans into Brain Microvascular Endothelial Cells

(2012) Wilber Sabiiti et al.   PLoS One

The Primary Target Organ of Cryptococcus gattii Is Different from That of Cryptococcus neoformans in a Murine Model

(2012) P. Ngamskulrungroj et al.   mBio

Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients

(2011) Guanggan Hu et al.   BMC GENOMICS

A Major Role for Capsule-Independent Phagocytosis-Inhibitory Mechanisms in Mammalian Infection by Cryptococcus neoformans

(2011) Cheryl D. Chun et al.   Cell Host & Microbe

Environmental prevalence ofCryptococcus neoformansandCryptococcus gattiiin India: An update

(2011) Anuradha Chowdhary et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Catch me if you can: phagocytosis and killing avoidance by Cryptococcus neoformans

(2011) Rocío García-Rodas et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Effects of microplusin, a copper-chelating antimicrobial peptide, against Cryptococcus neoformans

(2011) Fernanda D. Silva et al.   FEMS MICROBIOLOGY LETTERS

Invasion ofCryptococcus neoformansinto Human Brain Microvascular Endothelial Cells Is Mediated through the Lipid Rafts-Endocytic Pathway via the Dual Specificity Tyrosine Phosphorylation-regulated Kinase 3 (DYRK3)

(2011) Sheng-He Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paradoxical roles of alveolar macrophages in the host response to Cryptococcus neoformans

(2011) Travis J. McQuiston et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Comparisons of clinical features and mortality of cryptococcal meningitis between patients with and without human immunodeficiency virus infection

(2011) Yi-Chien Lee et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Clinical, Epidemiological and Outcome Features of Patients with Cryptococcosis in Uberaba, Minas Gerais, Brazil

(2011) Delio José Mora et al.   MYCOPATHOLOGIA

Ten Challenges on Cryptococcus and Cryptococcosis

(2011) Maurizio Del Poeta et al.   MYCOPATHOLOGIA

Evidence that the Human Pathogenic Fungus Cryptococcus neoformans var. grubii May Have Evolved in Africa

(2011) Anastasia P. Litvintseva et al.   PLoS One

Cryptococcus neoformans Requires a Functional Glycolytic Pathway for Disease but Not Persistence in the Host

(2011) M. S. Price et al.   mBio

Glycosaminoglycan Binding Facilitates Entry of a Bacterial Pathogen into Central Nervous Systems

(2011) Yung-Chi Chang et al.   PLoS Pathogens

Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans

(2011) Qing-Ming Qin et al.   PLoS Pathogens

Low Diversity Cryptococcus neoformans Variety grubii Multilocus Sequence Types from Thailand Are Consistent with an Ancestral African Origin

(2011) Sitali P. Simwami et al.   PLoS Pathogens

Histopathology of the arachnoid granulations and brain in HIV-associated cryptococcal meningitis: correlation with cerebrospinal fluid pressure

(2010) Angela Loyse et al.   AIDS

A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease

(2010) Tran TH Chau et al.   BMC INFECTIOUS DISEASES

Cost‐Effectiveness of Serum Cryptococcal Antigen Screening to Prevent Deaths among HIV‐Infected Persons with a CD4+Cell Count ⩽100 Cells/μL Who Start HIV Therapy in Resource‐Limited Settings

(2010) David B. Meya et al.   CLINICAL INFECTIOUS DISEASES

Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America

(2010) John R. Perfect et al.   CLINICAL INFECTIOUS DISEASES

Survival Defects of Cryptococcus neoformans Mutants Exposed to Human Cerebrospinal Fluid Result in Attenuated Virulence in an Experimental Model of Meningitis

(2010) A. Lee et al.   INFECTION AND IMMUNITY

Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain

(2010) Meiqing Shi et al.   JOURNAL OF CLINICAL INVESTIGATION

Paucity of Initial Cerebrospinal Fluid Inflammation in Cryptococcal Meningitis Is Associated with Subsequent Immune Reconstitution Inflammatory Syndrome

(2010) David R. Boulware et al.   JOURNAL OF INFECTIOUS DISEASES

Intracellular transport of Toxoplasma gondii through the blood–brain barrier

(2010) Sabrina M. Lachenmaier et al.   JOURNAL OF NEUROIMMUNOLOGY

In-hospital mortality of HIV-infected cryptococcal meningitis patients withC. gattiiandC. neoformansinfection in Gaborone, Botswana

(2010) Katherine T. Steele et al.   MEDICAL MYCOLOGY

Cryptococcal meningitis in non-HIV-infected patients in a Chinese tertiary care hospital, 1997–2007

(2010) Li-Ping Zhu et al.   MEDICAL MYCOLOGY

Ctr2 Links Copper Homeostasis to Polysaccharide Capsule Formation and Phagocytosis Inhibition in the Human Fungal Pathogen Cryptococcus neoformans

(2010) Cheryl D. Chun et al.   PLoS One

The Human Fungal Pathogen Cryptococcus neoformans Escapes Macrophages by a Phagosome Emptying Mechanism That Is Inhibited by Arp2/3 Complex-Mediated Actin Polymerisation

(2010) Simon A. Johnston et al.   PLoS Pathogens

Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity

(2010) Laura H. Okagaki et al.   PLoS Pathogens

Fungal Cell Gigantism during Mammalian Infection

(2010) Oscar Zaragoza et al.   PLoS Pathogens

Role of Phospholipases in Fungal Fitness, Pathogenicity, and Drug Development – Lessons from Cryptococcus Neoformans

(2010) Julianne Teresa Djordjevic   Frontiers in Microbiology

High ongoing burden of cryptococcal disease in Africa despite antiretroviral roll out

(2009) Joseph N Jarvis et al.   AIDS

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Robust Th1 and Th17 Immunity Supports Pulmonary Clearance but Cannot Prevent Systemic Dissemination of Highly Virulent Cryptococcus neoformans H99

(2009) Yanmei Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Cryptococcal Urease Promotes the Accumulation of Immature Dendritic Cells and a Non-Protective T2 Immune Response within the Lung

(2009) John J. Osterholzer et al.   AMERICAN JOURNAL OF PATHOLOGY

Cryptococcosis in Solid Organ Transplant Recipients

(2009) N. Singh et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Combination Flucytosine and High‐Dose Fluconazole Compared with Fluconazole Monotherapy for the Treatment of Cryptococcal Meningitis: A Randomized Trial in Malawi

(2009) Jesse C. Nussbaum et al.   CLINICAL INFECTIOUS DISEASES

Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection byCryptococcus neoformans

(2009) Kiem Vu et al.   EUKARYOTIC CELL

Isolation and Characterization ofCryptococcus neoformansSpores Reveal a Critical Role for Capsule Biosynthesis Genes in Spore Biogenesis

(2009) Michael R. Botts et al.   EUKARYOTIC CELL

Role of Ferroxidases in Iron Uptake and Virulence ofCryptococcus neoformans

(2009) Won Hee Jung et al.   EUKARYOTIC CELL

Elucidating the Pathogenesis of Spores from the Human Fungal Pathogen Cryptococcus neoformans

(2009) S. S. Giles et al.   INFECTION AND IMMUNITY

Spores as Infectious Propagules of Cryptococcus neoformans

(2009) R. Velagapudi et al.   INFECTION AND IMMUNITY

Activity of Contemporary Antifungal Agents, Including the Novel Echinocandin Anidulafungin, Tested against Candida spp., Cryptococcus spp., and Aspergillus spp.: Report from the SENTRY Antimicrobial Surveillance Program (2006 to 2007)

(2009) S. A. Messer et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Cellular Elements of the Blood-Brain Barrier

(2009) Jorge Correale et al.   NEUROCHEMICAL RESEARCH

Cryptococcosis in children

(2009) Cecília Bittencourt Severo et al.   Paediatric Respiratory Reviews

Surface-Associated Plasminogen Binding of Cryptococcus neoformans Promotes Extracellular Matrix Invasion

(2009) Jamal Stie et al.   PLoS One

Genetic Diversity of the Cryptococcus Species Complex Suggests that Cryptococcus gattii Deserves to Have Varieties

(2009) Popchai Ngamskulrungroj et al.   PLoS One

The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation

(2009) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diploids in the Cryptococcus neoformans Serotype A Population Homozygous for the α Mating Type Originate via Unisexual Mating

(2009) Xiaorong Lin et al.   PLoS Pathogens

Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells

(2008) Ambrose Jong et al.   CELLULAR MICROBIOLOGY

Capsule enlargement inCryptococcus neoformansconfers resistance to oxidative stress suggesting a mechanism for intracellular survival

(2008) Oscar Zaragoza et al.   CELLULAR MICROBIOLOGY

Outcomes of Cryptococcal Meningitis in Uganda Before and After the Availability of Highly Active Antiretroviral Therapy

(2008) Andrew Kambugu et al.   CLINICAL INFECTIOUS DISEASES

Evidence of a Role for Monocytes in Dissemination and Brain Invasion by Cryptococcus neoformans

(2008) C. Charlier et al.   INFECTION AND IMMUNITY

Metabolic adaptation inCryptococcus neoformansduring early murine pulmonary infection

(2008) Guanggan Hu et al.   MOLECULAR MICROBIOLOGY

Mechanisms of microbial traversal of the blood–brain barrier

(2008) Kwang Sik Kim   NATURE REVIEWS MICROBIOLOGY

Iron Source Preference and Regulation of Iron Uptake in Cryptococcus neoformans

(2008) Won Hee Jung et al.   PLoS Pathogens

Pulmonary Cryptococcosis in Solid Organ Transplant Recipients: Clinical Relevance of Serum Cryptococcal Antigen

(2007) N. Singh et al.   CLINICAL INFECTIOUS DISEASES