Providing β-lactams a helping hand: targeting the AmpC β-lactamase induction pathway

Overexpression of AmpC and Efflux Pumps in Pseudomonas aeruginosa Isolates from Bloodstream Infections: Prevalence and Impact on Resistance in a Spanish Multicenter Study

(2011) Gabriel Cabot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

AmpG Inactivation Restores Susceptibility of Pan-β-Lactam-Resistant Pseudomonas aeruginosa Clinical Strains

(2011) Laura Zamorano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa β-lactamase induction requires two permeases, AmpG and AmpP

(2011) Kok-Fai Kong et al.   BMC MICROBIOLOGY

Molecular Basis of 1,6-Anhydro Bond Cleavage and Phosphoryl Transfer byPseudomonas aeruginosa1,6-Anhydro-N-acetylmuramic Acid Kinase

(2011) John-Paul Bacik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Shape: Two-Dimensional Questions and Possibilities

(2010) Kevin D. Young   Annual Review of Microbiology

ampG Gene of Pseudomonas aeruginosa and Its Role in  -Lactamase Expression

(2010) Y. Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

NagZ Inactivation Prevents and Reverts  -Lactam Resistance, Driven by AmpD and PBP 4 Mutations, in Pseudomonas aeruginosa

(2010) L. Zamorano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of a New Cephalosporin, CXA-101 (FR264205), against  -Lactam-Resistant Pseudomonas aeruginosa Mutants Selected In Vitro and after Antipseudomonal Treatment of Intensive Care Unit Patients

(2010) B. Moya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Current Challenges in Antimicrobial Chemotherapy

(2010) Carine Bebrone et al.   DRUGS

Discovery of anti-TB agents that target the cell-division protein FtsZ

(2010) Kunal Kumar et al.   Future Medicinal Chemistry

Activity of BAL30376 (monobactam BAL19764 + BAL29880 + clavulanate) versus Gram-negative bacteria with characterized resistance mechanisms

(2010) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Crystal Structure of the AmpR Effector Binding Domain Provides Insight into the Molecular Regulation of Inducible AmpC β-Lactamase

(2010) Misty D. Balcewich et al.   JOURNAL OF MOLECULAR BIOLOGY

FtsZ in Bacterial Cytokinesis: Cytoskeleton and Force Generator All in One

(2010) H. P. Erickson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Challenging and emerging pathogens in cystic fibrosis

(2010) A.M.M. de Vrankrijker et al.   Paediatric Respiratory Reviews

Inactivation of the Glycoside Hydrolase NagZ Attenuates Antipseudomonal  -Lactam Resistance in Pseudomonas aeruginosa

(2009) A. Asgarali et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Updated Functional Classification of  -Lactamases

(2009) K. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

AmpC  -Lactamases

(2009) G. A. Jacoby   CLINICAL MICROBIOLOGY REVIEWS

Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

(2009) P. D. Lister et al.   CLINICAL MICROBIOLOGY REVIEWS

The clinical consequences of antimicrobial resistance

(2009) Louis B Rice   CURRENT OPINION IN MICROBIOLOGY

Targeting FtsZ for antibacterial therapy: a promising avenue

(2009) Sonia Kapoor et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The complexed structure and antimicrobial activity of a non-β-lactam inhibitor of AmpC β-lactamase

(2009) Rachel A. Powers et al.   PROTEIN SCIENCE

Insight into a strategy for attenuating AmpC-mediated β-lactam resistance: Structural basis for selective inhibition of the glycoside hydrolase NagZ

(2009) Misty D. Balcewich et al.   PROTEIN SCIENCE

β-Lactam Resistance Response Triggered by Inactivation of a Nonessential Penicillin-Binding Protein

(2009) Bartolomé Moya et al.   PLoS Pathogens

Role of ampD Homologs in Overproduction of AmpC in Clinical Isolates of Pseudomonas aeruginosa

(2008) A. J. Schmidtke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Benefit of Having Multiple ampD Genes for Acquiring  -Lactam Resistance without Losing Fitness and Virulence in Pseudomonas aeruginosa

(2008) B. Moya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanistic insights into glycosidase chemistry

(2008) David J Vocadlo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

How Bacteria Consume Their Own Exoskeletons (Turnover and Recycling of Cell Wall Peptidoglycan)

(2008) J. T. Park et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity

(2008) D. J. Haydon et al.   SCIENCE

Lytic transglycosylases: Bacterial space-making autolysins

(2007) Edie Scheurwater et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Synthesis and Use of Mechanism-Based Protein-Profiling Probes for Retaining β-d-Glucosaminidases Facilitate Identification ofPseudomonas aeruginosaNagZ

(2007) Keith A. Stubbs et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY