The antioxidant paradox: what are antioxidants and how should they be used in a therapeutic context for cancer

Mitochondrial oxidative stress is the achille’s heel of melanoma cells resistant to Braf-mutant inhibitor

(2015) Paola Corazao-Rozas et al.   Oncotarget

Role of c-Met/Phosphatidylinositol 3-Kinase (PI3k)/Akt Signaling in Hepatocyte Growth Factor (HGF)-mediated Lamellipodia Formation, Reactive Oxygen Species (ROS) Generation, and Motility of Lung Endothelial Cells

(2014) Peter V. Usatyuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation and Novel Action of Thymidine Phosphorylase in Non-Small Cell Lung Cancer: Crosstalk with Nrf2 and HO-1

(2014) Magdalena Tertil et al.   PLoS One

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

(2013) Kelly Casey Carroll et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia

(2012) Chie Ishikawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Targeting NADPH oxidases for the treatment of cancer and inflammation

(2012) Michael Y. Bonner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Pathways: Context-Dependent Approaches to Notch Targeting as Cancer Therapy

(2012) A. M. Egloff et al.   CLINICAL CANCER RESEARCH

AMPK activation reduces vascular permeability and airway inflammation by regulating HIF/VEGFA pathway in a murine model of toluene diisocyanate-induced asthma

(2012) Seoung Ju Park et al.   INFLAMMATION RESEARCH

Combination therapy of imiquimod and gentian violet for cutaneous melanoma metastases

(2012) Jack L. Arbiser et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The Mitochondrial ATPase Inhibitory Factor 1 Triggers a ROS-Mediated Retrograde Prosurvival and Proliferative Response

(2012) Laura Formentini et al.   MOLECULAR CELL

Stabilization of HIF-2α through redox regulation of mTORC2 activation and initiation of mRNA translation

(2012) B K Nayak et al.   ONCOGENE

ROS-Scavenger and Radioprotective Efficacy of the New PrC-210 Aminothiol

(2012) Daniel D. Peebles et al.   RADIATION RESEARCH

Anti-Invasive Adjuvant Therapy with Imipramine Blue Enhances Chemotherapeutic Efficacy Against Glioma

(2012) J. M. Munson et al.   Science Translational Medicine

Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3

(2012) Kyoung Ah Kang et al.   TUMOR BIOLOGY

A Key Role for NOX4 in Epithelial Cell Death During Development of Lung Fibrosis

(2011) Stephanie Carnesecchi et al.   ANTIOXIDANTS & REDOX SIGNALING

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype

(2011) Antero Salminen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

(2011) Sarah Garrido-Urbani et al.   PLoS One

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

(2011) C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thiol-disulfide exchanges modulate aldo–keto reductase family 1 member B10 activity and sensitivity to inhibitors

(2010) Yi Shen et al.   BIOCHIMIE

Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

(2010) Jessie Villanueva et al.   CANCER CELL

High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer

(2010) T. Jiang et al.   CANCER RESEARCH

Sirt1 acts in association with PPAR  to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

(2010) A. Planavila et al.   CARDIOVASCULAR RESEARCH

Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines

(2010) Mohd. A. Yusuf et al.   FREE RADICAL BIOLOGY AND MEDICINE

Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2)

(2010) Junfang Deng et al.   LIVER INTERNATIONAL

Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent

(2009) Levi E. Fried et al.   ANTIOXIDANTS & REDOX SIGNALING

Honokiol-mediated Inhibition of PI3K/mTOR Pathway

(2009) Courtney Crane et al.   JOURNAL OF IMMUNOTHERAPY

Efficacy of topical application of eosin for ulcerated hemangiomas

(2009) Moshe Lapidoth et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

(2008) Jonas Sjölund et al.   JOURNAL OF CLINICAL INVESTIGATION

DNMT1 as a Molecular Target in a Multimodality-Resistant Phenotype in Tumor Cells

(2008) M. V. Mishra et al.   MOLECULAR CANCER RESEARCH

The reactive oxygen-driven tumor: relevance to melanoma

(2008) Levi Fried et al.   Pigment Cell & Melanoma Research

A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells

(2008) B. Boivin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA