Review
Nutrition & Dietetics
Ashish Ranjan Sharma, Yeon-Hee Lee, Altanzul Bat-Ulzii, Srijan Chatterjee, Manojit Bhattacharya, Chiranjib Chakraborty, Sang-Soo Lee
Summary: Skeletal disabilities are a burden on the population, and using natural therapies with fewer side effects is key. Flavonoids, found in dietary supplements, have been found to have a positive effect on bone remodeling. However, their bioavailability and absorption limit their use.
Article
Biochemistry & Molecular Biology
Fausto Zamparini, Carlo Prati, Paola Taddei, Andrea Spinelli, Michele Di Foggia, Maria Giovanna Gandolfi
Summary: The aim of this study was to analyze the properties and bioactivity of three newly introduced premixed bioceramic root canal sealers containing different calcium silicates. The results showed that these sealers meet the required standards and release biologically relevant ions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Food Science & Technology
Indeewarie Hemamali Dissanayake, Valeria Zak, Kirandeep Kaur, Kayla Jaye, Zahra Ayati, Dennis Chang, Chun Guang Li, Deep Jyoti Bhuyan
Summary: Australian native fruits and vegetables are rich in nutrients and have therapeutic properties. Numerous studies have been conducted to understand their nutritional and phytochemical profiles. However, research on vegetables is limited compared to fruits.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Multidisciplinary Sciences
Naween Anand, Kevin Barry, Jennifer N. Neu, David E. Graf, Qing Huang, Haidong Zhou, Theo Siegrist, Hitesh J. Changlani, Christianne Beekman
Summary: This study demonstrates the capability of capacitive torque magnetometry in investigating magnetic-field induced phase transitions in spin-ice materials and characterizing the magneto-chemical potential. The authors built a magnetic phase diagram of Ho2Ti2O7 and found that the magneto-chemical potential depends on the spin sublattice involved in the transition.
NATURE COMMUNICATIONS
(2022)
Review
Allergy
Victoria Mutua, Laurel J. Gershwin
Summary: Activated neutrophils release NETs to capture and destroy microbes, but they also cause inflammation and tissue damage. The role of NETs in autoimmune and autoinflammatory diseases is being studied, and inhibition of NETosis may reduce disease severity.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Kai-Hung Cheng, Gregory P. Contreras, Ting-Yu Yeh
Summary: Cardiovascular toxicity is the leading cause of death in cancer patients undergoing treatment. This review explores the impact of neutrophil extracellular traps (NETs) on cancer, cardiovascular events, and cancer treatment-related cardiovascular toxicity (CTRCT). The evidence suggests that NETs play an important role in cancer proliferation, metastasis, and incident cardiovascular events, but further research is needed to understand their relationship with cardio-oncology and CTRCT.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Materials Science, Ceramics
Peng Du, Tao Xiang, Xinxin Yang, Guoqiang Xie
Summary: A bioactive titanate layer was synthesized in situ on the porous Ti-based bulk metallic glass, which not only provides a bone-bonding capability but also modulates the release rate of Cu2+ ions, reducing the potential biological toxicity. Thorough analysis before and after the chemical treatment was conducted to study the structure, morphology, mechanical characteristics, corrosion resistance, and antibacterial properties.
CERAMICS INTERNATIONAL
(2023)
Article
Plant Sciences
Breno Martins de Deus, Conceicao Fernandes, Adriana K. Molina, Virginie Xavier, Tania C. S. P. Pires, Filipa Mandim, Sandrina A. Heleno, Tiane C. Finimundy, Lillian Barros
Summary: Consumer demand for natural and healthier products has increased interest in the bioactive and therapeutic properties of plant extracts. This study evaluates the phenolic compounds profile, bioactivities, and toxicities of plant extracts from eight European flora species. The results suggest that these extracts have potential as natural preservatives due to their richness in bioactive compounds.
Article
Biochemistry & Molecular Biology
Huizhong Hu, Dengwu Li, Ruxue Bai, Weiping Zhang, Hong Luo, Enping Yu
Summary: The present study assessed the chemodiversity and bioactivity of Juniperus essential oils from the Qinghai-Tibet Plateau. The results showed that these oils have a diverse range of chemical components and potential antioxidant and antibacterial effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Nemanja Teslic, Jovana Kojic, Branislava Dermanovic, Ljubisa Saric, Nikola Maravic, Mladenka Pestoric, Bojana Saric
Summary: Sour cherry pomace filling (SCPF) and commercial sour cherry filling (CSCF) were compared in terms of food safety, chemical composition, bioactivity, quality, sensory properties, and thermal stability. SCPF had higher fiber and mineral content compared to CSCF, while CSCF was more spreadable and had lower storage and loss modulus values. However, both fillings had acceptable rheological and textural behavior. Consumer preference tests showed no significant preference for either filling. SCPF could be used as a raw material in the bakery fruit fillings industry, contributing to the valorization of food industry by-products.
Review
Chemistry, Medicinal
Md Shahinozzaman, Diana N. Obanda, Shinkichi Tawata
Summary: Propolis is a resinous substance collected and processed by honeybees to seal cracks in beehives. It is categorized into seven groups based on plant source and location. Pacific, Okinawa, and Taiwanese propolis are Macaranga-type propolis with potential pharmacological benefits.
PHYTOTHERAPY RESEARCH
(2021)
Article
Medicine, Research & Experimental
Karolina Jakubczyk, Aleksandra Tuchowska, Katarzyna Janda-Milczarek
Summary: Hydrolates, by-products of plant hydrodistillation, have high antioxidant potential depending on plant species, origin, plant part, and preservation method. The study demonstrates the wide application of hydrosols in cosmetics and their potential value in skincare and agri-food industry.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Review
Immunology
Pengyan Fa, Benjamin G. Ke, Abigail Dupre, Allan Tsung, Hongji Zhang
Summary: Nonalcoholic fatty liver disease (NAFLD) is a growing global health concern. Neutrophil extracellular traps (NETs) play a key role in the development and progression of NAFLD by promoting oxidative stress and inflammation.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Edwin Andrew Ofudje, James Asamu Akande, Ezekiel Folorunso Sodiya, Gabriel O. Ajayi, Adeniyi John Ademoyegun, Abdullah G. Al-Sehemi, Yasar N. Kavil, Ammar M. Bakheet
Summary: There is a high demand for bioactive and non-toxic biomaterials in tissue engineering applications. Hydroxyapatite (HAp) and HAp/clay nanocomposites have been developed to mimic natural HAp and provide special properties to the biomaterial. The functional groups properties, crystallinity, morphology, and behavior in saline solution and simulated body fluids were analyzed, confirming the potential application of HAp/clay nanocomposites in bone tissue engineering.
SCIENTIFIC REPORTS
(2023)
Review
Chemistry, Medicinal
Gitishree Das, Kyung Jik Lim, Ourlad Alzeus G. Tantengco, Harold M. Carag, Sandra Goncalves, Anabela Romano, Swagat Kumar Das, Ericsson Coy-Barrera, Han-Seung Shin, Erick Paul Gutierrez-Grijalva, J. Basilio Heredia, Jayanta Kumar Patra
Summary: Cactus species are plants that grow in arid regions and are used for food, medicine, and decoration. Recent research indicates that cactus materials contain valuable natural products, but many species are endangered due to overexploitation.
PHYTOTHERAPY RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Satabdi Datta, Diptiman Choudhury, Amlan Das, Dipanwita Das Mukherjee, Moumita Dasgupta, Shreya Bandopadhyay, Gopal Chakrabarti
Correction
Biochemistry & Molecular Biology
Satabdi Datta, Diptiman Choudhury, Amlan Das, Dipanwita Das Mukherjee, Moumita Dasgupta, Shreya Bandopadhyay, Gopal Chakrabarti
Article
Biochemistry & Molecular Biology
Amlan Das, Maruthi Kumar Narayanam, Santanu Paul, Pritha Mukhnerjee, Suvranil Ghosh, Debabrata Ghosh Dastidar, Subhendu Chakrabarty, Arnab Ganguli, Biswarup Basu, Mahadeb Pal, Urmi Chatterji, Sushanta K. Banerjee, Parimal Karmakar, Dalip Kumar, Gopal Chakrabarti
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Article
Oncology
Gargi Maity, Arnab Ghosh, Vijayalaxmi Gupta, Inamul Haque, Sandipto Sarkar, Amian Das, Kakali Dhar, Sneha Bhavanasi, Sumedha S. Gunewardena, Daniel D. Von Hoff, Sanku Mallik, Suman Kambhampati, Sushanta K. Banerjee, Snigdha Banerjee
MOLECULAR CANCER THERAPEUTICS
(2019)
Article
Biotechnology & Applied Microbiology
Debabrata G. Dastidar, Amlan Das, Satabdi Datta, Suvranil Ghosh, Mahadeb Pal, Neeraj S. Thakur, Uttam C. Banerjee, Gopal Chakrabarti
Article
Plant Sciences
Santanu Paul, Subhendu Chakrabarty, Suvranil Ghosh, Debasish Nag, Amlan Das, Debabrata Ghosh Dastidar, Moumita Dasgupta, Naibedya Dutta, Mandavi Kumari, Mahadeb Pal, Gopal Chakrabarti
Article
Microbiology
Payel Paul, Poulomi Chakraborty, Ahana Chatterjee, Ranojit K. Sarker, Debabrata Ghosh Dastidar, Taraknath Kundu, Niloy Sarkar, Amlan Das, Prosun Tribedi
Summary: Staphylococcus aureus, a Gram-positive opportunistic microorganism, poses a major threat to public healthcare through biofilm formation. This study found that 1,4-naphthoquinone has significant antimicrobial and antibiofilm activity against Staphylococcus aureus, potentially offering a promising approach to inhibit biofilm formation caused by this pathogen.
ARCHIVES OF MICROBIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Poulomi Chakraborty, Payel Paul, Monika Kumari, Surajit Bhattacharjee, Mukesh Singh, Debasish Maiti, Debabrata Ghosh Dastidar, Yusuf Akhter, Taraknath Kundu, Amlan Das, Prosun Tribedi
Summary: Thymoquinone exhibited significant antibiofilm activity against Pseudomonas aeruginosa by accumulating ROS and inhibiting the expression of quorum sensing gene lasI. Combinatorial application of thymoquinone with other reported antibiofilm agents, such as tryptophan and tetrazine-capped silver nanoparticles, showed enhanced antibiofilm efficiency. The combination of these antibiofilm molecules resulted in ROS accumulation in cells, leading to the inhibition of biofilm formation with minimal cytotoxicity.
FOLIA MICROBIOLOGICA
(2021)
Article
Pharmacology & Pharmacy
Amlan Das, Inamul Haque, Priyanka Ray, Arnab Ghosh, Debasmita Dutta, Mohiuddin Quadir, Archana De, Sumedha Gunewardena, Indranil Chatterjee, Snigdha Banerjee, Scott Weir, Sushanta K. Banerjee
Summary: This study demonstrates that EGCG activates CCN5 to inhibit in vitro cell viability, reverse TNBC cells' stemness, and suppress tumor growth. Additionally, EGCG-loaded nanoparticles are found to be more effective in suppressing tumors compared to free-EGCG.
PHARMACOLOGY RESEARCH & PERSPECTIVES
(2021)
Article
Microbiology
Payel Paul, Sharmistha Das, Sudipta Chatterjee, Aditya Shukla, Poulomi Chakraborty, Sarita Sarkar, Debasish Maiti, Amlan Das, Prosun Tribedi
Summary: The study investigated the impact of 1,4-naphthoquinone on pre-existing biofilm of Staphylococcus aureus, revealing the key role of extracellular DNA in biofilm integrity. The generation of reactive oxygen species was found to degrade the eDNA and lead to the disintegration of pre-existing biofilm.
ARCHIVES OF MICROBIOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Meenu Mehta, Keshav Raj Paudel, Shakti Dhar Shukla, Venkata Sita Rama Raju Allam, Vinod Kumar Kannaujiya, Nisha Panth, Amlan Das, Vipan Kumar Parihar, Amlan Chakraborty, Md Khadem Ali, Niraj Kumar Jha, Dikaia Xenaki, Qian Peter Su, Peter Richard Wich, Jon Adams, Philip Michael Hansbro, Dinesh Kumar Chellappan, Brian Gregory George Oliver, Kamal Dua
Summary: NFicB is a significant player in respiratory diseases, and NFicB decoy ODNs have been utilized in the treatment of chronic inflammatory diseases. However, challenges such as poor pharmacokinetic profile of naked decoy ODNs exist. Structural modifications and nanotechnology offer potential solutions in enhancing the pharmacokinetic profiles of therapeutic substances.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Biotechnology & Applied Microbiology
Payel Paul, Poulomi Chakraborty, Ranojit K. Sarker, Ahana Chatterjee, Debasish Maiti, Amlan Das, Sukhendu Mandal, Surajit Bhattacharjee, Debabrata Ghosh Dastidar, Prosun Tribedi
Summary: The study showed that tryptophan can effectively inhibit biofilm formation of Staphylococcus aureus by interfering with its quorum-sensing property and downregulating specific gene expression. Furthermore, tryptophan did not exhibit cytotoxicity at tested concentrations.
Article
Microbiology
Sharmistha Das, Payel Paul, Sudipta Chatterjee, Poulomi Chakraborty, Ranojit K. Sarker, Amlan Das, Debasish Maiti, Prosun Tribedi
Summary: Piperine, a plant-based alkaloid, has shown considerable antimicrobial activity against Staphylococcus aureus, inhibiting its biofilm formation at lower concentrations without compromising microbial growth.
ARCHIVES OF MICROBIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Sudipta Chatterjee, Payel Paul, Poulomi Chakraborty, Sharmistha Das, Ranojit Kumar Sarker, Subhasis Sarkar, Amlan Das, Prosun Tribedi
Summary: The study demonstrated that cuminaldehyde has strong antibiofilm activity against Pseudomonas aeruginosa without showing antimicrobial activity. Cuminaldehyde treatment led to the accumulation of cellular reactive oxygen species, inhibiting microbial biofilm formation. Ascorbic acid exposure could restore the biofilm-forming ability of cuminaldehyde-treated cells.
Article
Multidisciplinary Sciences
Dipanjan Ghosh, Debabrata Ghosh Dastidar, Kamalesh Roy, Arnab Ghosh, Debanjan Mukhopadhyay, Nilabja Sikdar, Nidhan K. Biswas, Gopal Chakrabarti, Amlan Das
Summary: This study used computational analysis to predict the potential mechanism by which statin drugs inhibit SARS-CoV-2 pathogenesis. The researchers found that fluvastatin can bind to multiple target proteins of SARS-CoV-2 and exhibits strong antiviral efficacy.
SCIENTIFIC REPORTS
(2022)
