Azapeptides and their therapeutic potential

Development of Nitrile-Based Peptidic Inhibitors of Cysteine Cathepsins

(2010) Maxim Frizler et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structural Optimization of Azadipeptide Nitriles Strongly Increases Association Rates and Allows the Development of Selective Cathepsin Inhibitors

(2010) Maxim Frizler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aza-1,2,3-triazole-3-alanine Synthesis via Copper-Catalyzed 1,3-Dipolar Cycloaddition on Aza-progargylglycine

(2010) Caroline Proulx et al.   JOURNAL OF ORGANIC CHEMISTRY

Solution-phase submonomer diversification of aza-dipeptide building blocks and their application in aza-peptide and aza-DKP synthesis

(2010) Carine B. Bourguet et al.   JOURNAL OF PEPTIDE SCIENCE

Copper-CatalyzedN-Arylation of Semicarbazones for the Synthesis of Aza-Arylglycine-Containing Aza-Peptides

(2010) Caroline Proulx et al.   ORGANIC LETTERS

Structural basis of substrate specificity in the serine proteases

(2010) John J. Perona et al.   PROTEIN SCIENCE

Aza-Peptidyl Michael Acceptor and Epoxide Inhibitors—Potent and Selective Inhibitors of Schistosoma mansoni and Ixodes ricinus Legumains (Asparaginyl Endopeptidases)

(2009) Asli Ovat et al.   JOURNAL OF MEDICINAL CHEMISTRY

Exploring Side-Chain Diversity by Submonomer Solid-Phase Aza-Peptide Synthesis

(2009) David Sabatino et al.   ORGANIC LETTERS

Azadipeptide Nitriles: Highly Potent and Proteolytically Stable Inhibitors of Papain-Like Cysteine Proteases

(2008) Reik Löser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, antiviral activity, and conformational studies of a P3 aza-peptide analog of a potent macrocyclic tripeptide HCV protease inhibitor

(2008) John T. Randolph et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Benzophenone semicarbazone protection strategy for synthesis of aza-glycine containing aza-peptides

(2008) Carine B. Bourguet et al.   BIOPOLYMERS

Aza-peptidyl Michael Acceptors. A New Class of Potent and Selective Inhibitors of Asparaginyl Endopeptidases (Legumains) from Evolutionarily Diverse Pathogens

(2008) Marion G. Götz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of N′-substituted Ddz-protected hydrazines and their application in solid phase synthesis of aza-peptides

(2008) Noam S. Freeman et al.   TETRAHEDRON

A Convenient Synthesis of Substituted Pyrazolidines and Azaproline Derivatives through Highly Regio- and Diastereoselective Reduction of 2-Pyrazolines

(2007) Jesús M. de los Santos et al.   JOURNAL OF ORGANIC CHEMISTRY