Structure-based antivirals for emerging and neglected RNA viruses: an emerging field for medicinal chemistry in academia

The Twenty-Third International Conference on Antiviral Research

(2010)   ANTIVIRAL RESEARCH

Identification of SARS-like coronaviruses in horseshoe bats (Rhinolophus hipposideros) in Slovenia

(2010) Danijela Rihtarič et al.   ARCHIVES OF VIROLOGY

Recent Advances in Targeting Viral Proteases for the Discovery of Novel Antivirals

(2010) Holger Steuber et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antiviral therapy: quo vadis?

(2010) Erik De Clercq   Future Medicinal Chemistry

Ecoepidemiology and Complete Genome Comparison of Different Strains of Severe Acute Respiratory Syndrome-Related Rhinolophus Bat Coronavirus in China Reveal Bats as a Reservoir for Acute, Self-Limiting Infection That Allows Recombination Events

(2010) S. K. P. Lau et al.   JOURNAL OF VIROLOGY

Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease

(2010) Shengnan Zhang et al.   Protein & Cell

Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode

(2010) Shuai Chen et al.   Protein & Cell

The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic

(2009) Samuel Broder   ANTIVIRAL RESEARCH

The emerging academic drug-discovery sector

(2009) Paul G Wyatt   Future Medicinal Chemistry

Accelerating the drug-discovery process: new tools and technologies available to medicinal chemists

(2009) Luca F Raveglia et al.   Future Medicinal Chemistry

Medicinal chemistry at a crossroads: challenges and new possibilities

(2009) Iwao Ojima   Future Medicinal Chemistry

Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

(2009) Cheng-Chung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enterovirus 71 Outbreak in the People's Republic of China in 2008

(2009) F. Yang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China

(2009) Yong Zhang et al.   JOURNAL OF CLINICAL VIROLOGY

Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans

(2009) J. Yuan et al.   JOURNAL OF GENERAL VIROLOGY

Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept

(2009) Michael Lisurek et al.   MOLECULAR DIVERSITY

Sensitized Detection of Inhibitory Fragments and Iterative Development of Non-Peptidic Protease Inhibitors by Dynamic Ligation Screening

(2008) Marco Florian Schmidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A case for developing antiviral drugs against polio

(2008) Marc S. Collett et al.   ANTIVIRAL RESEARCH

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents

(2008) Chih-Jung Kuo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A Structural View of the Inactivation of the SARS Coronavirus Main Proteinase by Benzotriazole Esters

(2008) Koen H.G. Verschueren et al.   CHEMISTRY & BIOLOGY

Selective inhibitors of picornavirus replication

(2008) Armando M. De Palma et al.   MEDICINAL RESEARCH REVIEWS

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

(2008) K. Ratia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The VIZIER project: Preparedness against pathogenic RNA viruses

(2007) B. Coutard et al.   ANTIVIRAL RESEARCH