6-desfluoroquinolones as HIV-1 Tat-mediated transcription inhibitors

Role of the HIV-1 Positive Elongation Factor P-TEFb and Inhibitors Thereof

(2012) Yan Wang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein

(2010) A. Loregian et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibition of porcine endogenous retrovirus (PERV) replication by HIV-1 gene expression inhibitors

(2009) Minyi Shi et al.   ANTIVIRAL RESEARCH

Identification of Flavopiridol Analogues that Selectively Inhibit Positive Transcription Elongation Factor (P-TEFb) and Block HIV-1 Replication

(2009) Akbar Ali et al.   CHEMBIOCHEM

2-Phenylquinolones as Inhibitors of the HIV-1 Tat-TAR Interaction

(2009) Barbara Gatto et al.   ChemMedChem

The 4-Quinolone-3-Carboxylic Acid Motif as a Multivalent Scaffold in Medicinal Chemistry

(2009) Claudia Mugnaini et al.   CURRENT MEDICINAL CHEMISTRY

Strategies for the design of RNA-binding small molecules

(2009) Fareed Aboul-ela   Future Medicinal Chemistry

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

(2009) S. Ludwig   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication

(2009) Serena Massari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Twenty-Six Years of Anti-HIV Drug Discovery: Where Do We Stand and Where Do We Go?

(2009) Youcef Mehellou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synergistic Activation of HIV-1 Expression by Deacetylase Inhibitors and Prostratin: Implications for Treatment of Latent Infection

(2009) Sophie Reuse et al.   PLoS One

Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein

(2009) A. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

(2009) Andrea Savarino et al.   Retrovirology

Targeting host factors: A novel rationale for the management of hepatitis C virus

(2009) Mahmoud Aboelneen Khattab   WORLD JOURNAL OF GASTROENTEROLOGY

Resistance to novel drug classes

(2009) Anne-Genevieve Marcelin et al.   Current Opinion in HIV and AIDS

A 6-Aminoquinolone Compound, WC5, with Potent and Selective Anti-Human Cytomegalovirus Activity

(2008) B. Mercorelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Studies on anti-HIV quinolones: New insights on the C-6 position

(2008) Serena Massari et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition

(2008) Giuseppe Manfroni et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting RNA with Small Molecules

(2008) Jason R. Thomas et al.   CHEMICAL REVIEWS

Cellular Reservoirs of HIV-1 and their Role in Viral Persistence

(2008) Aikaterini Alexaki et al.   CURRENT HIV RESEARCH

Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection

(2008) Lin Shen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eradication of HIV: current challenges and new directions

(2008) M. D. Marsden et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Structure−Activity Relationship Study on Anti-HIV 6-Desfluoroquinolones

(2008) Oriana Tabarrini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology

(2008) S WANG et al.   TRENDS IN PHARMACOLOGICAL SCIENCES