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Title
Inhibitors of MDM2 and MDMX: a structural perspective
Authors
Keywords
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Journal
Future Medicinal Chemistry
Volume 1, Issue 6, Pages 1075-1094
Publisher
Future Science, LTD
Online
2009-09-21
DOI
10.4155/fmc.09.75
References
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Related references
Note: Only part of the references are listed.- Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
- (2014) Grzegorz Popowicz et al. CELL CYCLE
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- (2010) Anna Czarna et al. CELL CYCLE
- β-Peptides with improved affinity for hDM2 and hDMX
- (2009) Elizabeth A. Harker et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes
- (2009) Joerg Kallen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Function for the RING Finger Domain in the Allosteric Control of MDM2 Conformation and Activity
- (2009) Bartosz Wawrzynow et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Study of MDM2 Binding to p53-Analogues: Affinity, Helicity, and Applicability to Drug Design
- (2009) Ori Kalid et al. Journal of Chemical Information and Modeling
- Targeting Mdm2 and Mdmx in Cancer Therapy: Better Living through Medicinal Chemistry?
- (2009) Mark Wade et al. MOLECULAR CANCER RESEARCH
- Structural Biology of the Tumor Suppressor p53
- (2008) Andreas C. Joerger et al. Annual Review of Biochemistry
- Acidic domain is indispensable for MDM2 to negatively regulate the acetylation of p53
- (2008) Qian Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Isoquinolin‐1‐one Inhibitors of the MDM2–p53 Interaction
- (2008) Ulli Rothweiler et al. ChemMedChem
- Small molecular weight protein–protein interaction antagonists—an insurmountable challenge?
- (2008) Alexander Dömling CURRENT OPINION IN CHEMICAL BIOLOGY
- c-Abl Phosphorylates Hdmx and Regulates Its Interaction with p53
- (2008) Valentina Zuckerman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Analysis of Chemical Shift Changes Reveals the Binding Modes of Isoindolinone Inhibitors of the MDM2-p53 Interaction
- (2008) Christiane Riedinger et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer
- (2008) Sanjeev Shangary et al. MOLECULAR CANCER THERAPEUTICS
- Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
- (2008) S. Shangary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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