Review
Agronomy
Demeke Teklu, Dawd Gashu, Edward J. M. Joy, Tilahun Amede, Martin R. Broadley
Summary: Micronutrient deficiencies (MNDs) affect a significant proportion of the global population. Agronomic biofortification can help increase the concentration of essential minerals in food crops to improve human dietary intake. However, its feasibility depends on various factors such as access to fertilizers and considerations of crop type, genotype, climate, soils, and soil mineral interactions. This paper reviews the available literature on the potential effectiveness and challenges of agronomic biofortification in addressing MNDs.
Review
Biochemistry & Molecular Biology
Ling Jiang, Simon Strobbe, Dominique Van Der Straeten, Chunyi Zhang
Summary: Micronutrient deficiencies, including shortages of vitamins and minerals, have long-term effects on billions of people's health, learning ability, and economic losses. Biofortification of multiple micronutrients plays a key role in combating malnutrition, but balancing plant growth with human nutrient requirements presents a challenge. Integrating new breeding technologies with metabolic pathway modification can facilitate crop biofortification and alleviate hidden hunger in target populations.
Review
Horticulture
Selly D. Msungu, Arnold A. Mushongi, Pavithravani B. Venkataramana, Ernest R. Mbega
Summary: Micronutrient deficiency is a major problem, especially in developing countries where maize is the main source of calories. Vitamin A deficiency can cause various health issues and economic losses among vulnerable groups. Strategies such as supplementation, fortification, and diversification have been used, but rural residents still lack access to these alternatives. Biofortification of maize with higher provitamin A content shows promise in alleviating vitamin A deficiency, especially in sub-Saharan Africa.
SCIENTIA HORTICULTURAE
(2022)
Review
Agronomy
P. Sushree Shyamli, Sumi Rana, Sandhya Suranjika, Mehanathan Muthamilarasan, Ajay Parida, Manoj Prasad
Summary: Improving the nutritional content of graminaceous crops is crucial for ensuring nutritional security, and conventional and biotechnological approaches are essential for addressing this issue. Micronutrient deficiency can have serious health consequences, highlighting the importance of identifying genetic determinants underlying micronutrient biosynthesis. Studies on major cereals have led to the identification of genes, alleles, and QTLs controlling grain micronutrient content, while research on minor cereals such as millets is needed to fully understand the genetic basis of micronutrient traits.
THEORETICAL AND APPLIED GENETICS
(2021)
Article
Biochemistry & Molecular Biology
Sichul Lee, Md Mizanor Rahman, Hiromi Nakanishi, Naoko K. K. Nishizawa, Gynheung An, Hong Gil Nam, Jong-Seong Jeon
Summary: Simultaneous activation of OsNAS2 and OsNAS3 can enhance the accumulation of iron and zinc in rice grains and increase the plant's tolerance to metal deficiency and excess metal availability.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Prashant Kandwal, Toru Fujiwara, Takehiro Kamiya
Summary: Nearly 2 billion people in developing countries suffer from nutrient deficiency, particularly iron and zinc deficiency. Biofortification of crops through breeding is a promising solution to address this hidden hunger. In this study, a mutant, 1095_k, was characterized for its high grain iron and zinc concentration. The mutant showed similar yield components as the wild type in a 5-year field trial. Further analysis revealed a non-sense mutation in the OsVIT2 gene, a transporter responsible for iron transportation in vacuoles. F2 crosses between 1095_k and wild type with the mutation showed higher grain iron and zinc concentration, indicating the potential of 1095_k as a breeding material for biofortification of iron and zinc.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Bidya Bhushan Gupta, Sumit Kumar Mishra, Sampath Kumar Banoth, Suchi Baliyan, Harsh Chauhan
Summary: Iron and zinc deficiencies are common causes of hidden hunger globally. This study successfully enhanced the iron and zinc content in rice through transgenic techniques. The expression of dicot and monocot Ferritins along with OsNAS2 gene significantly improved grain iron content. The developed transgenic lines have the potential to meet the recommended dietary requirement for rice.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Abdul Rehman, Muhammad Farooq, Aman Ullah, Ahmad Nawaz, Muhammad Moeen ud Din, Babar Shahzad
Summary: Zinc deficiency affects wheat productivity and human nutrition. This study examined the effects of seed priming with zinc on wheat performance and grain biofortification. The results showed that seed priming with zinc sulfate improved wheat physiology, yield, and grain zinc content.
CROP & PASTURE SCIENCE
(2022)
Article
Plant Sciences
Lan Wang, Haiyong Xia, Xiaojing Li, Yuetong Qiao, Yanhui Xue, Xilong Jiang, Wei Yan, Yumin Liu, Yanfang Xue, Lingan Kong
Summary: Different source-sink manipulations can affect the accumulation of zinc and other nutrient elements in wheat grains at different soil zinc application levels, indicating interactions among various nutrient elements are crucial for wheat grain quality and biofortification. Manipulating source-sink flow can provide insights for alleviating human malnutrition through wheat grain biofortification.
Article
Agronomy
Aysha Kiran, Abdul Wakeel, Khalid Mahmood, Rafia Mubaraka, Hafsa, Stephan M. Haefele
Summary: Micronutrient malnutrition is a global health challenge that affects almost half of the global population. Biofortification, combining agronomic interventions and genetic improvement of food crops, has proven to be a promising and economical approach to increase the concentration of essential micronutrients in staple crops. Several developing countries have successfully biofortified crops such as maize, rice, wheat, beans, pearl millet, sweet potato, and cassava with increased concentrations of Fe, Zn, or provitamin A.
Review
Plant Sciences
Yuta Kawakami, Navreet K. Bhullar
Summary: Iron deficiency in humans is a widespread issue worldwide, and iron biofortification of rice has shown promising results in increasing grain iron concentration. However, there are still many aspects to be addressed and future studies should focus on resolving these issues to enhance rice biofortification strategies.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Review
Plant Sciences
B. P. Mallikarjuna Swamy, Balram Marathi, Ana I. F. Ribeiro-Barros, Mark Ian C. Calayugan, Felipe Klein Ricachenevsky
Summary: Rice is the most suitable model species for studying Fe homeostasis and biofortification, with over 90 Fe QTLs identified and multiple genes associated with Fe translocation and accumulation. Current research focuses on the transport, accumulation, and distribution of Fe in rice grains.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Agronomy
Jing Zeng, Han Li, Yifan Tang, Ping Qing
Summary: This paper examines the impact of biofortification adoption on return on investment (ROI) and provides empirical support. The empirical results show that the adoption of biofortification has a positive and significant impact on ROI, with comparatively high annual income adopters and female adopters benefiting more.
Review
Nutrition & Dietetics
Om Prakash Gupta, Amit Kumar Singh, Archana Singh, Gyanendra Pratap Singh, Kailash C. Bansal, Swapan K. Datta
Summary: Alleviating problems related to micronutrients in children and women is a challenge, and wheat is a crucial crop for biofortification. Natural genetic variability in wheat has been used to breed micronutrient-rich varieties, and several countries have released biofortified wheat cultivars for commercial cultivation.
FRONTIERS IN NUTRITION
(2022)
Article
Agronomy
Asif Naeem, Muhammad Aslam, Mumtaz Ahmad, Muhammad Asif, Mustafa Atilla Yazici, Ismail Cakmak, Abdul Rashid
Summary: This study examined the effectiveness of a combined foliar application of iodine, selenium, and zinc in increasing the micronutrient content of rice grains. The results showed variations in the response to foliar spray among different rice cultivars.
Article
Plant Sciences
Bo Li, Caitlin Byrt, Jiaen Qiu, Ute Baumann, Maria Hrmova, Aurelie Evrard, Alexander A. T. Johnson, Kenneth D. Birnbaum, Gwenda M. Mayo, Deepa Jha, Sam W. Henderson, Mark Tester, Mathew Gilliham, Stuart J. Roy
Article
Agricultural Engineering
Shyama C. Fernando, Jason Q. D. Goodger, Samantha Saucedo Gutierrez, Alexander A. T. Johnson, Ian E. Woodrow
INDUSTRIAL CROPS AND PRODUCTS
(2016)
Article
Biotechnology & Applied Microbiology
Julien Bonneau, Ute Baumann, Jesse Beasley, Yuan Li, Alexander A. T. Johnson
PLANT BIOTECHNOLOGY JOURNAL
(2016)
Editorial Material
Plant Sciences
Roslyn Gleadow, Alexander Johnson, Michael Tausz
FUNCTIONAL PLANT BIOLOGY
(2013)
Article
Food Science & Technology
Bianca Kyriacou, Katie L. Moore, David Paterson, Martin D. de Jonge, Daryl L. Howard, James Stangoulis, Mark Tester, Enzo Lombi, Alexander A. T. Johnson
JOURNAL OF CEREAL SCIENCE
(2014)
Article
Plant Sciences
Nataliya Kovalchuk, Jessica Smith, Natalia Bazanova, Tatiana Pyvovarenko, Rohan Singh, Neil Shirley, Ainur Ismagul, Alexander Johnson, Andrew S. Milligan, Maria Hrmova, Peter Langridge, Sergiy Lopato
JOURNAL OF EXPERIMENTAL BOTANY
(2012)
Article
Biochemistry & Molecular Biology
Siavash Foroughi, Alan J. M. Baker, Ute Roessner, Alexander A. T. Johnson, Antony Bacic, Damien L. Callahan
Article
Biochemistry & Molecular Biology
Olivier Cotsaftis, Darren Plett, Alexander A. T. Johnson, Harkamal Walia, Clyde Wilson, Abdelbagi M. Ismail, Timothy J. Close, Mark Tester, Ute Baumann
Article
Plant Sciences
Peter M. Kopittke, Martin D. de Jonge, Peng Wang, Brigid A. McKenna, Enzo Lombi, David J. Paterson, Daryl L. Howard, Simon A. James, Kathryn M. Spiers, Chris G. Ryan, Alexander A. T. Johnson, Neal W. Menzies
Article
Plant Sciences
Wan M. Aizat, James M. Preuss, Alexander A. T. Johnson, Mark A. Tester, Carolyn J. Schultz
PHYSIOLOGIA PLANTARUM
(2011)
Article
Biotechnology & Applied Microbiology
Nataliya Kovalchuk, Ming Li, Finni Wittek, Nicolas Reid, Rohan Singh, Neil Shirley, Ainur Ismagul, Serik Eliby, Alex Johnson, Andrew S. Milligan, Maria Hrmova, Peter Langridge, Sergiy Lopato
PLANT BIOTECHNOLOGY JOURNAL
(2010)
Article
Biotechnology & Applied Microbiology
Nataliya Kovalchuk, Wei Wu, Omid Eini, Natalia Bazanova, Margaret Pallotta, Neil Shirley, Rohan Singh, Ainur Ismagul, Serik Eliby, Alexander Johnson, Peter Langridge, Sergiy Lopato
PLANT BIOTECHNOLOGY JOURNAL
(2012)
Article
Multidisciplinary Sciences
Alexander A. T. Johnson, Bianca Kyriacou, Damien L. Callahan, Lorraine Carruthers, James Stangoulis, Enzo Lombi, Mark Tester
Article
Biochemistry & Molecular Biology
Oscar Carey-Fung, Martin O'Brien, Jesse T. Beasley, Alexander A. T. Johnson
Summary: This study utilizes gene editing technology to generate T-DNA-free iro3 mutants and reveals the regulatory role of OsIRO3 in rice iron homeostasis. The iro3 mutants show stunted growth and altered expression of iron-related genes under iron-deficient conditions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)