Mitochondrial DNA: more than an evolutionary bystander

Mitochondrial ROS production correlates with, but does not directly regulate lifespan in drosophila

(2016) Alberto Sanz et al.   Aging-US

Adenosine Nucleotide Biosynthesis and AMPK Regulate Adult Life Span and Mediate the Longevity Benefit of Caloric Restriction in Flies

(2013) Drew Stenesen et al.   Cell Metabolism

In vivo male fertility is affected by naturally occurring mitochondrial haplotypes

(2013) Winston K.W. Yee et al.   CURRENT BIOLOGY

From evolutionary bystander to master manipulator: the emerging roles for the mitochondrial genome as a modulator of nuclear gene expression

(2013) Martin P Horan et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Quaternary protein modeling to predict the function of DNA variation found in human mitochondrial cytochrome c oxidase

(2013) Martin Patrick Horan et al.   JOURNAL OF HUMAN GENETICS

Diet influences the intake target and mitochondrial functions of Drosophila melanogaster males

(2013) Nicolas Pichaud et al.   MITOCHONDRION

Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease

(2013) G. Hudson et al.   NEUROLOGY

Bioenergetics in human evolution and disease: implications for the origins of biological complexity and the missing genetic variation of common diseases

(2013) D. C. Wallace   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Elevated oxidative damage is correlated with reduced fitness in interpopulation hybrids of a marine copepod

(2013) F. S. Barreto et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Humanin: a harbinger of mitochondrial-derived peptides?

(2013) Changhan Lee et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition

(2012) Mark S. Sharpley et al.   CELL

NATURALLY OCCURRING MITOCHONDRIAL DNA HAPLOTYPES EXHIBIT METABOLIC DIFFERENCES: INSIGHT INTO FUNCTIONAL PROPERTIES OF MITOCHONDRIA

(2012) Nicolas Pichaud et al.   EVOLUTION

mtDNA haplotypes differ in their probability of being eliminated by a mass die-off in an abundant seabird

(2012) S V Drovetski et al.   HEREDITY

Paternal transmission of mitochondrial DNA as an integral part of mitochondrial inheritance in metapopulations of Drosophila simulans

(2012) J N Wolff et al.   HEREDITY

Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration

(2012) Nicolas Pichaud et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster

(2012) C.C. Correa et al.   MITOCHONDRION

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A

(2012) Richard D. W. Kelly et al.   NUCLEIC ACIDS RESEARCH

Polar and brown bear genomes reveal ancient admixture and demographic footprints of past climate change

(2012) W. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary Trade-Offs, Pareto Optimality, and the Geometry of Phenotype Space

(2012) O. Shoval et al.   SCIENCE

The effect of ethidium bromide and chloramphenicol on mitochondrial biogenesis in primary human fibroblasts

(2012) Li-Pin Kao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Global DNA methylation levels are modulated by mitochondrial DNA variants

(2012) Dina Bellizzi et al.   Epigenomics

Expression Profiling of Attenuated Mitochondrial Function Identifies Retrograde Signals in Drosophila

(2012) William A. Freije et al.   G3-Genes Genomes Genetics

Thermal sensitivity of mitochondrial functions in permeabilized muscle fibers from two populations of Drosophila simulans with divergent mitotypes

(2011) Nicolas Pichaud et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Incubation Temperature Affects Growth and Energy Metabolism in Blue Tit Nestlings

(2011) Andreas Nord et al.   AMERICAN NATURALIST

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

(2011) Heather M. O'Hagan et al.   CANCER CELL

Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis

(2011) Adeel Safdar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of respiratory chain activity in lymphocytes of patients with Alzheimer disease

(2011) Pollyana Feldhaus et al.   METABOLIC BRAIN DISEASE

Mitochondrial DNA variants in Drosophila melanogaster are expressed at the level of the organismal phenotype

(2011) W.C. Aw et al.   MITOCHONDRION

Are mitochondrial haplogroups associated with elite athletic status? A study on a Spanish cohort

(2011) Gisela Nogales-Gadea et al.   MITOCHONDRION

Untangling individual variation in natural populations: ecological, genetic and epigenetic correlates of long-term inequality in herbivory

(2011) C. M. HERRERA et al.   MOLECULAR ECOLOGY

Mitochondrial DNA Backgrounds Might Modulate Diabetes Complications Rather than T2DM as a Whole

(2011) Alessandro Achilli et al.   PLoS One

The Strength and Timing of the Mitochondrial Bottleneck in Salmon Suggests a Conserved Mechanism in Vertebrates

(2011) Jonci N. Wolff et al.   PLoS One

Gene Expression Pattern in Transmitochondrial Cytoplasmic Hybrid Cells Harboring Type 2 Diabetes-Associated Mitochondrial DNA Haplogroups

(2011) Seungwoo Hwang et al.   PLoS One

Positive Darwinian Selection in the Piston That Powers Proton Pumps in Complex I of the Mitochondria of Pacific Salmon

(2011) Michael R. Garvin et al.   PLoS One

Modes of Metabolic Compensation during Mitochondrial Disease Using the Drosophila Model of ATP6 Dysfunction

(2011) Alicia M. Celotto et al.   PLoS One

Experimental Evidence Supports a Sex-Specific Selective Sieve in Mitochondrial Genome Evolution

(2011) P. Innocenti et al.   SCIENCE

Cost of a Naturally Occurring Two–Amino Acid Deletion in Cytochrome c Oxidase Subunit 7A in Drosophila simulans

(2010) J. William O. Ballard et al.   AMERICAN NATURALIST

Somatic Mitochondrial DNA Mutations in Mammalian Aging

(2010) Nils-Göran Larsson   Annual Review of Biochemistry

EARLY LIFE BENEFITS AND LATER LIFE COSTS OF A TWO AMINO ACID DELETION IN DROSOPHILA SIMULANS

(2010) J. William O. Ballard et al.   EVOLUTION

Acute temperature resistance threshold in heart mitochondria: Febrile temperature activates function but exceeding it collapses the membrane barrier

(2010) Rasa Zukiene et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Thermal sensitivity of mitochondrial metabolism in two distinct mitotypes of Drosophila simulans: evaluation of mitochondrial plasticity

(2010) N. Pichaud et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Xenomitochondrial mice: Investigation into mitochondrial compensatory mechanisms

(2010) M.V. Cannon et al.   MITOCHONDRION

Impact of the Mitochondrial Genetic Background in Complex III Deficiency

(2010) Mari Carmen Gil Borlado et al.   PLoS One

Somatic Point Mutations in mtDNA Control Region Are Influenced by Genetic Background and Associated with Healthy Aging: A GEHA Study

(2010) Giuseppina Rose et al.   PLoS One

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells

(2010) D.-F. Suen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation

(2010) A. Zemach et al.   SCIENCE

PGC-1α in aging and anti-aging interventions

(2009) Rozalyn Anderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial bioenergetics as a major motive force of speciation

(2009) Moran Gershoni et al.   BIOESSAYS

mTOR and the control of whole body metabolism

(2009) Pazit Polak et al.   CURRENT OPINION IN CELL BIOLOGY

The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling

(2009) Stefanie K Tiefenböck et al.   EMBO JOURNAL

Can Indirect Tests Detect a Known Recombination Event in Human mtDNA?

(2009) D. J. White et al.   MOLECULAR BIOLOGY AND EVOLUTION

Evidence for Variation in the Effective Population Size of Animal Mitochondrial DNA

(2009) Gwenael Piganeau et al.   PLoS One

Long-lived Indy and calorie restriction interact to extend life span

(2009) P.-Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Climate shaped the worldwide distribution of human mitochondrial DNA sequence variation

(2009) F. Balloux et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reactive oxygen species as universal constraints in life-history evolution

(2009) D. K. Dowling et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The causes of mutation accumulation in mitochondrial genomes

(2009) M. Neiman et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Variation in mitochondrial genotype has substantial lifespan effects which may be modulated by nuclear background

(2008) David J. Clancy   AGING CELL

The adaptive evolution of the mammalian mitochondrial genome

(2008) Rute R da Fonseca et al.   BMC GENOMICS

New evidence of a mitochondrial genetic background paradox: Impact of the J haplogroup on the A3243G mutation

(2008) Denis Pierron et al.   BMC Medical Genetics

Nutritional Control of Protein Biosynthetic Capacity by Insulin via Myc in Drosophila

(2008) Aurelio A. Teleman et al.   Cell Metabolism

Insulin/TOR signaling in growth and homeostasis: A view from the fly world

(2008) Savraj S. Grewal   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease

(2008) Maik Hüttemann et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

(2008) Anthony HV Schapira   LANCET NEUROLOGY

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE

The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

(2008) Timothy Wai et al.   NATURE GENETICS

Lifespan and reproduction in Drosophila: New insights from nutritional geometry

(2008) K. P. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manipulating the Metazoan Mitochondrial Genome with Targeted Restriction Enzymes

(2008) H. Xu et al.   SCIENCE

A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations

(2008) Weiwei Fan et al.   SCIENCE

Nutritional Control of Reproductive Status in Honeybees via DNA Methylation

(2008) R. Kucharski et al.   SCIENCE

Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA

(2008) James Bruce Stewart et al.   PLOS BIOLOGY

Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna

(2008) Lars-Henrik Heckmann et al.   GENOME BIOLOGY