Capillary nano-immunoassays: advancing quantitative proteomics analysis, biomarker assessment, and molecular diagnostics

“Picolog,” a Synthetically-Available Bryostatin Analog, Inhibits Growth of MYC-Induced Lymphoma In Vivo

(2015) Brian A. DeChristopher et al.   Oncotarget

Residual bovine serum albumin (BSA) quantitation in vaccines using automated Capillary Western technology

(2014) John W. Loughney et al.   ANALYTICAL BIOCHEMISTRY

A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation

(2014) Kimberly C Wiegand et al.   BMC CANCER

Cancer-associated fibroblast promote transmigration through endothelial brain cells in three-dimensionalin vitromodels

(2014) Yoon Pyo Choi et al.   INTERNATIONAL JOURNAL OF CANCER

Dicer Knockdown Inhibits Endothelial Cell Tumor Growth via MicroRNA 21a-3p Targeting of Nox-4

(2014) Gayle M. Gordillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose Tissue μ-Crystallin Is a Thyroid Hormone-Binding Protein Associated With Systemic Insulin Sensitivity

(2014) Marta Serrano et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Capillary nano-immunoassay for Akt 1/2/3 and 4EBP1 phosphorylation in acute myeloid leukemia

(2014) Himalee Sabnis et al.   Journal of Translational Medicine

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

(2014) Feodor D Price et al.   NATURE MEDICINE

Antibody-based detection of protein phosphorylation status to track the efficacy of novel therapies using nanogram protein quantities from stem cells and cell lines

(2014) Mark Aspinall-O'Dea et al.   Nature Protocols

Nanoimmunoassay to Detect Responses in Head and Neck Cancer

(2014) Matthew A. Hubbard et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

A Novel Mouse Fgfr2 Mutant, Hobbyhorse (hob), Exhibits Complete XY Gonadal Sex Reversal

(2014) Pam Siggers et al.   PLoS One

Cancer Cells Differentially Activate and Thrive on De Novo Lipid Synthesis Pathways in a Low-Lipid Environment

(2014) Veerle W. Daniëls et al.   PLoS One

Examining the Protective Role of ErbB2 Modulation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

(2014) Sandy Eldridge et al.   TOXICOLOGICAL SCIENCES

Biological Profile of the Less Lipophilic and Synthetically More Accessible Bryostatin 7 Closely Resembles That of Bryostatin 1

(2013) Noemi Kedei et al.   ACS Chemical Biology

Angiogenic growth factors augment K-Cl cotransporter expression in erythroid cells via hypoxia-inducible factor-1α

(2013) Caryn S. Gonsalves et al.   AMERICAN JOURNAL OF HEMATOLOGY

Development of a capillary isoelectric focusing immunoassay to measure DJ-1 isoforms in biological samples

(2013) D. Besong Agbo et al.   ANALYTICAL BIOCHEMISTRY

Absolute quantitation of endogenous proteins with precision and accuracy using a capillary Western system

(2013) Jin-Qiu Chen et al.   ANALYTICAL BIOCHEMISTRY

Analysis of Amino-Terminal Variants of Amyloid-β Peptides by Capillary Isoelectric Focusing Immunoassay

(2013) Ute Haußmann et al.   ANALYTICAL CHEMISTRY

Oxytocin modulates mTORC1 pathway in the gut

(2013) Benjamin Y. Klein et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation

(2013) Carolyn Bentley et al.   BIOCHEMICAL JOURNAL

Targeted Quantitation of Proteins by Mass Spectrometry

(2013) Daniel C. Liebler et al.   BIOCHEMISTRY

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

(2013) S. Beurlet et al.   BLOOD

A Pan-BCL2 Inhibitor Renders Bone-Marrow-Resident Human Leukemia Stem Cells Sensitive to Tyrosine Kinase Inhibition

(2013) Daniel J. Goff et al.   Cell Stem Cell

Real-time nanoscale proteomic analysis of the novel multi-kinase pathway inhibitor rigosertib to measure the response to treatment of cancer

(2013) Alice C Fan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Label-retaining liver cancer cells are relatively resistant to sorafenib

(2013) Hong-Wu Xin et al.   GUT

Regulation of FOXO3 by phosphorylation and methylation in hepatitis C virus infection and alcohol exposure

(2013) Irina Tikhanovich et al.   HEPATOLOGY

A Specific PTPRC/CD45 Phosphorylation Event Governed by Stem Cell Chemokine CXCL12 Regulates Primitive Hematopoietic Cell Motility

(2013) Andrew J. K. Williamson et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification and Quantification of AKT Isoforms and Phosphoforms in Breast Cancer Using a Novel Nanofluidic Immunoassay

(2013) Demetris C. Iacovides et al.   MOLECULAR & CELLULAR PROTEOMICS

Capillary Isoelectric-Focusing Immunoassays to Study Dynamic Oncoprotein Phosphorylation and Drug Response to Targeted Therapies in Non–Small Cell Lung Cancer

(2013) Jin-Qiu Chen et al.   MOLECULAR CANCER THERAPEUTICS

Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules

(2013) H Guo et al.   ONCOGENE

Nanoproteomic analysis of extracellular receptor kinase-1/2 post-translational activation in microdissected human hyperplastic colon lesions

(2013) David A. Drew et al.   PROTEOMICS

LIFE SCIENCE TECHNOLOGIES: Not Your PI's Western Blot

(2013) A. Harding   SCIENCE

BIGH3 modulates adhesion and migration of hematopoietic stem and progenitor cells

(2013) Sofieke E Klamer et al.   Cell Adhesion & Migration

Charge Heterogeneity of Monoclonal Antibodies by Multiplexed Imaged Capillary Isoelectric Focusing Immunoassay with Chemiluminescence Detection

(2012) David A. Michels et al.   ANALYTICAL CHEMISTRY

Qualitative and quantitative evaluation of Simon™, a new CE-based automated Western blot system as applied to vaccine development

(2012) Richard R. Rustandi et al.   ELECTROPHORESIS

The F-BAR Protein PACSIN2 Regulates Epidermal Growth Factor Receptor Internalization

(2012) Bart-Jan de Kreuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

(2012) Zuyue Sun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Intermolecular Binding between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF- B Activation

(2012) C.-C. F. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Biological Responses to TGF-  in the Mammary Epithelium Show a Complex Dependency on Smad3 Gene Dosage with Important Implications for Tumor Progression

(2012) E. A. Kohn et al.   MOLECULAR CANCER RESEARCH

Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia

(2012) Alex Kentsis et al.   NATURE MEDICINE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pdx1 Is Post-Translationally Modified In vivo and Serine 61 Is the Principal Site of Phosphorylation

(2012) Thomas Frogne et al.   PLoS One

Microfluidic integration for automated targeted proteomic assays

(2012) A. J. Hughes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sin3a repressor complex is a master regulator of STAT transcriptional activity

(2012) Laura Icardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional protein microarray as molecular decathlete: A versatile player in clinical proteomics

(2012) Heng Zhu et al.   Proteomics Clinical Applications

Affinity-based microarrays for proteomic analysis of cancer tissues

(2012) Jörg D. Hoheisel et al.   Proteomics Clinical Applications

The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line

(2011) Noemi Kedei et al.   BIOCHEMICAL PHARMACOLOGY

Defining the role of TORC1/2 in multiple myeloma

(2011) P. Maiso et al.   BLOOD

ELISA and Multiplex Technologies for Cytokine Measurement in Inflammation and Aging Research

(2011) S. X. Leng et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Treatment of higher risk myelodysplastic syndrome patients unresponsive to hypomethylating agents with ON 01910.Na

(2011) Mahesh Seetharam et al.   LEUKEMIA RESEARCH

Market access challenges in the EU for high medical value diagnostic tests

(2011) Iain Miller et al.   Personalized Medicine

A multicentre phase II gene expression profiling study of putative relationships between tumour biomarkers and clinical response with erlotinib in non-small-cell lung cancer

(2010) E.-H. Tan et al.   ANNALS OF ONCOLOGY

Proximity ligation assays: a recent addition to the proteomics toolbox

(2010) Irene Weibrecht et al.   Expert Review of Proteomics

A Gene-centric Human Proteome Project

(2010)   MOLECULAR & CELLULAR PROTEOMICS

Reverse phase protein microarrays advance to use in clinical trials

(2010) Claudius Mueller et al.   Molecular Oncology

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

(2010) David M Rissin et al.   NATURE BIOTECHNOLOGY

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

KRAS Mutation Testing in Colorectal Cancer

(2009) Thomas P. Plesec et al.   ADVANCES IN ANATOMIC PATHOLOGY

Antibody-Based Protein Multiplex Platforms: Technical and Operational Challenges

(2009) A. A. Ellington et al.   CLINICAL CHEMISTRY

Multiplexed Cell Signaling Analysis of Metastatic and Nonmetastatic Colorectal Cancer Reveals COX2-EGFR Signaling Activation as a Potential Prognostic Pathway Biomarker

(2009) Mariaelena Pierobon et al.   Clinical Colorectal Cancer

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

(2009) Terri A Addona et al.   NATURE BIOTECHNOLOGY

Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens

(2009) Alice C Fan et al.   NATURE MEDICINE

Confirmation of Gene Expression-Based Prediction of Survival in Non-Small Cell Lung Cancer

(2008) N. L. Guo et al.   CLINICAL CANCER RESEARCH

A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities

(2008) K. S. Garman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA