High-dose recombinant human bone morphogenetic protein-2 impacts histological and biomechanical properties of a cervical spine fusion segment: results from a sheep model

Effectiveness and Harms of Recombinant Human Bone Morphogenetic Protein-2 in Spine Fusion

(2013) Rongwei Fu et al.   ANNALS OF INTERNAL MEDICINE

The effect of dose on rhBMP-2 signaling, delivered via collagen sponge, on osteoclast activation and in vivo bone resorption

(2013) Ri Youn Kim et al.   BIOMATERIALS

Biological performance of a polycaprolactone-based scaffold plus recombinant human morphogenetic protein-2 (rhBMP-2) in an ovine thoracic interbody fusion model

(2013) Mostyn R N O Yong et al.   EUROPEAN SPINE JOURNAL

The signaling and functions of heterodimeric bone morphogenetic proteins

(2012) Jing Guo et al.   CYTOKINE & GROWTH FACTOR REVIEWS

rhBMP-2/Calcium Phosphate Matrix Induces Bone Formation While Limiting Transient Bone Resorption in a Nonhuman Primate Core Defect Model

(2012) Howard J. Seeherman et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Multilevel anterior cervical discectomy and fusion with and without rhBMP-2: a comparison of dysphagia rates and outcomes in 150 patients

(2012) Daniel C. Lu et al.   JOURNAL OF NEUROSURGERY-SPINE

Cyclic-RGD Is as Effective as rhBMP-2 in Anterior Interbody Fusion of the Sheep Cervical Spine

(2012) Matti Scholz et al.   SPINE

Recombinant human bone morphogenetic protein-2: adverse events reported to the Manufacturer and User Facility Device Experience database

(2012) Emily Jane Woo   Spine Journal

Complications following autologous bone graft harvesting from the iliac crest and using the RIA: A systematic review

(2011) Rozalia Dimitriou et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Osteolysis in Transforaminal Lumbar Interbody Fusion with Bone Morphogenetic Protein-2

(2011) CPT Jeffrey B. Knox et al.   SPINE

Adjacent vertebral body osteolysis with bone morphogenetic protein use in transforaminal lumbar interbody fusion

(2011) Melvin D. Helgeson et al.   Spine Journal

A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned

(2011) Eugene J. Carragee et al.   Spine Journal

High Doses of Bone Morphogenetic Protein 2 Induce Structurally Abnormal Bone and Inflammation In Vivo

(2011) Janette N. Zara et al.   TISSUE ENGINEERING PART A

rhBMP-2 Induces Transient Bone Resorption Followed by Bone Formation in a Nonhuman Primate Core-Defect Model

(2010) Howard J. Seeherman et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Symptomatic ectopic bone formation after off-label use of recombinant human bone morphogenetic protein-2 in transforaminal lumbar interbody fusion

(2010) Nan-Fu Chen et al.   JOURNAL OF NEUROSURGERY-SPINE

Complications Related to Osteobiologics Use in Spine Surgery

(2010) Thomas E. Mroz et al.   SPINE

Wnt and PPARγ signaling in osteoblastogenesis and adipogenesis

(2009) Ichiro Takada et al.   Nature Reviews Rheumatology

Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment

(2009) Jeffrey M. Toth et al.   SPINE

Use of polyetheretherketone spacer and recombinant human bone morphogenetic protein-2 in the cervical spine: a radiographic analysis

(2009) Paul Klimo et al.   Spine Journal

Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program

(2008) S. Muruganandan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Posterior lumbar interbody fusion using rhBMP-2

(2008) Hans Jörg Meisel et al.   EUROPEAN SPINE JOURNAL

The safety and efficacy of anterior cervical discectomy and fusion with polyetheretherketone spacer and recombinant human bone morphogenetic protein–2: a review of 200 patients

(2008) Luis M. Tumialán et al.   JOURNAL OF NEUROSURGERY-SPINE

Prospective nonrandomized comparison of an allograft with bone morphogenic protein versus an iliac-crest autograft in anterior cervical discectomy and fusion

(2007) Glenn Robin Buttermann   Spine Journal

Neurologic impairment from ectopic bone in the lumbar canal: a potential complication of off-label PLIF/TLIF use of bone morphogenetic protein-2 (BMP-2)

(2007) David A. Wong et al.   Spine Journal