Pathogen activators of plasminogen

Rapid Binding of Plasminogen to Streptokinase in a Catalytic Complex Reveals a Three-step Mechanism

(2014) Ingrid M. Verhamme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toxin–antitoxin-stabilized reporter plasmids for biophotonic imaging of Group A streptococcus

(2013) Jacelyn M. S. Loh et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Site-restricted plasminogen activation mediated by group A streptococcal streptokinase variants

(2013) Simon M. Cook et al.   BIOCHEMICAL JOURNAL

Full Time Course Kinetics of the Streptokinase-Plasminogen Activation Pathway

(2013) Miranda Nolan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Streptokinase as a Virulence Determinant of Streptococcus pyogenes – Potential for Therapeutic Targeting

(2012) Mark J. Walker et al.   CURRENT DRUG TARGETS

Characterization of Streptokinases from Group A Streptococci Reveals a Strong Functional Relationship That Supports the Coinheritance of Plasminogen-binding M Protein and Cluster 2b Streptokinase

(2012) Yueling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the native plasminogen reveals an activation-resistant compact conformation

(2012) Y. XUE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Streptokinase variants fromStreptococcus pyogenesisolates display altered plasminogen activation characteristics - implications for pathogenesis

(2012) Simon M. Cook et al.   MOLECULAR MICROBIOLOGY

Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice

(2012) H. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The X-ray Crystal Structure of Full-Length Human Plasminogen

(2012) Ruby H.P. Law et al.   Cell Reports

Exploration of the host haemostatic system by group A streptococcus: implications in searching for novel antimicrobial therapies

(2011) H. SUN   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Streptococcal M1 protein constructs a pathological host fibrinogen network

(2011) Pauline Macheboeuf et al.   NATURE

Skizzle Is a Novel Plasminogen- and Plasmin-binding Protein fromStreptococcus agalactiaeThat Targets Proteins of Human Fibrinolysis to Promote Plasmin Generation

(2010) Karen G. Wiles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasminogen Substrate Recognition by the Streptokinase-Plasminogen Catalytic Complex Is Facilitated by Arg253, Lys256, and Lys257in the Streptokinase β-Domain and Kringle 5 of the Substrate

(2009) Anthony C. Tharp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of the central domain of streptokinase in substrate plasminogen docking and processing revealed by site-directed mutagenesis

(2009) Anita Chaudhary et al.   PROTEIN SCIENCE

Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation

(2008) Jason D. McArthur et al.   FASEB JOURNAL

Rapid-reaction Kinetic Characterization of the Pathway of Streptokinase-Plasmin Catalytic Complex Formation

(2008) Ingrid M. Verhamme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY