Article
Psychiatry
Michael K. Leuchter, Benjamin M. Rosenberg, Giuditta Schapira, Nicole R. Wong, Andrew F. Leuchter, Anastasia L. McGlade, David E. Krantz, Nathaniel D. Ginder, Jonathan C. Lee, Scott A. Wilke, Reza Tadayonnejad, Jennifer Levitt, Katharine G. Marder, Michelle G. Craske, Marco Iacoboni
Summary: This study provides preliminary evidence for the feasibility of accelerating extinction learning in patients with spider phobia using iTBS rTMS, and suggests that the treatment outcomes may be intensity-dependent.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Neurosciences
Vanesa Pytel, Maria Nieves Cabrera-Martin, Alfonso Delgado-Alvarez, Jose Luis Ayala, Paloma Balugo, Cristina Delgado-Alonso, Miguel Yus, Maria Teresa Carreras, Jose Luis Carreras, Jorge Matias-Guiu, Jordi A. Matias-Guiu
Summary: This study found that using personalized targeting repetitive transcranial magnetic stimulation can improve language ability, patient and caregiver perception of change, apathy, and depression in patients with PPA, and there is an increase in metabolism in various brain regions after treatment, indicating enhancement of synaptic activity.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Behavioral Sciences
Mara Alves, Patricia Figueiredo, Ana Raposo
Summary: Effective use of conceptual knowledge engages semantic representation and control processes to access information in a goal-driven manner. Neuropsychological findings of patients with degraded knowledge or disrupted control converge with neuroimaging evidence and delineate the neural segregation of representation and control mechanisms. This fMRI study on young and older adults revealed age-related differences in brain activation during a covert naming task, suggesting reorganization of neural activity in older adults for semantic representation and increased control resources in the elderly for atypical concepts. The findings highlight the dynamic nature of semantic control interplaying with conceptual representations across different age groups.
Article
Behavioral Sciences
Marjolaine Cohen, Gwendoline Mahe, Pascal Zesiger, Marina Laganaro
Summary: This study used EEG recordings to investigate the development of naming skills in children aged 7-12 years and how they interact with age and reading level variations. Results showed that age and reading level had similar effects on letter naming, while they had different effects on picture naming, with reading level specifically affecting the N1 time-interval. Age was found to be the only predictor of variance in the global electric field at scalp for both letter and picture naming tasks in microstate analysis.
Article
Medicine, General & Internal
Seong Hoon Bae, Seo Jin Moon, Jeong Gum Lee, Yun Kyung Yim, Hee So Oh, Dong Hee Han, In Seok Moon
Summary: The study compared the effects of rTMS and tDCS treatments for chronic tinnitus, showing comparable results in reducing tinnitus symptoms, with tDCS possibly being more cost-effective.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Geriatrics & Gerontology
Youichi Saitoh, Koichi Hosomi, Tomoo Mano, Yasushi Takeya, Shinji Tagami, Nobuhiko Mori, Akiyoshi Matsugi, Yasutomo Jono, Hideaki Harada, Tomomi Yamada, Akimitsu Miyake
Summary: This study evaluated the efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) for Japanese patients with Alzheimer's disease. The results showed that the treatment had beneficial effects on cognitive function under certain conditions, and no serious adverse events occurred. This study provides important evidence for further clinical trials.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Immunology
Yi-Wen Bai, Qi-Hao Yang, Pei-Jie Chen, Xue-Qiang Wang
Summary: Neuropathic pain is a common condition caused by damage or disease to the nervous system, and is associated with excessive inflammation. Repetitive transcranial magnetic stimulation (rTMS) is an adjunctive treatment for neuropathic pain, which can regulate the neuroinflammation system to produce analgesic effects.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Neurosciences
Heidi Ala-Salomaki, Jan Kujala, Mia Liljestrom, Riitta Salmelin
Summary: The study aimed to identify source-localized evoked activity and cortical oscillations with high test-retest reliability in healthy individuals during a delayed picture naming paradigm, demonstrating the applicability of MEG measurements in clinical assessments and language production research.
Article
Multidisciplinary Sciences
Shixie Jiang, Jingyu Huang, Hao Yang, Ryan Wagoner, F. Andrew Kozel, Glenn Currier, Huabei Jiang
Summary: This study utilized a novel diffuse optical tomography (DOT) device to investigate the neurophysiological effects of rTMS in depressed and healthy subjects. The results demonstrated that depressed subjects had a delayed and less robust response to rTMS with decreased volume of activation compared to healthy subjects.
SCIENTIFIC REPORTS
(2021)
Review
Psychiatry
Gerasimos N. Konstantinou, Alisson P. Trevizol, Jonathan Downar, Shelley F. McMain, Fidel Vila-Rodriguez, Zafiris J. Daskalakis, M. Blumberger
Summary: The literature on the application of repetitive transcranial magnetic stimulation (rTMS) in Borderline Personality Disorder (BPD) is unclear, but existing studies suggest that rTMS is a well-tolerated treatment in patients with BPD. Further research is needed to determine the efficacy of rTMS in different symptoms of BPD and to establish the best cortical targets and stimulation protocols. Longitudinal studies combining evidence-based psychotherapy with rTMS may be a promising approach to improve outcomes for this population in the future.
PSYCHIATRY RESEARCH
(2021)
Article
Psychology, Biological
Hsin-Pei Lin, Anna K. Kuhlen, Alissa Melinger, Sabrina Aristei, Rasha Abdel Rahman
Summary: This study used event-related brain potentials to investigate the impact of semantic similarity on different planning stages during language production. The findings showed that closely related items induced semantic blocking effects, while distantly related items did not. Initial facilitation led to easier object recognition, while later cycles experienced increased difficulties, demonstrating a trade-off between facilitatory priming and interfering lexical competition.
Article
Behavioral Sciences
Cristina Polito, Francesca Conca, Gaia C. Santi, Valentina Esposito, Silvia P. Caminiti, Cecilia Boccalini, Valentina Berti, Carmen Morinelli, Salvatore Mazzeo, Alessandra Marcone, Sandro Iannaccone, Valentina Bessi, Sandro Sorbi, Daniela Perani, Stefano F. Cappa, Eleonora Catricala
Summary: This article investigates the effectiveness of two Italian naming tests, CaGi and SAND, in distinguishing PPA variants. SAND outperforms CaGi in differentiating among PPA variants, while CaGi is more useful in characterizing the nature of naming impairment.
Article
Neurosciences
Brodie J. Hand, Ashley Merkin, George M. Opie, Ulf Ziemann, John G. Semmler
Summary: The purpose of this study was to examine the effect of rppTMS on M1 excitability and visuomotor skill acquisition in young and older adults. The results showed that rppTMS can increase M1 excitability and improve visuomotor skill acquisition in both young and older adults.
Review
Biochemistry & Molecular Biology
Xuemei Zong, Jie Gu, Deqin Geng, Dianshuai Gao
Summary: rTMS has shown promising therapeutic value in rodent models of stroke, Alzheimer's disease, vascular dementia, and Parkinson's disease. However, the optimal protocols and exact target of action for this therapy remain to be determined. Therefore, further research is needed to bridge the translation gap between rodent experiments and clinical application, which might lead to new directions in the treatment of multiple neurological disorders.
NEUROCHEMISTRY INTERNATIONAL
(2022)
Article
Clinical Neurology
A. M. Heath, M. Brewer, J. Yesavage, M. W. McNerney
Summary: This study demonstrates that repetitive transcranial magnetic stimulation (rTMS) applied between learning and retrieval phases can effectively improve memory in mice by promoting synaptic connections and maintaining key pathways in neurons.