Article
Surgery
Alpa Patel, Karina S. Patel, Lauren R. Teras
Summary: Excess body fatness is associated with various health outcomes, including premature mortality, cardiovascular disease, type 2 diabetes, and different types of cancer. Expert panels have concluded that there is sufficient evidence linking excess body fatness to 13 types of cancer, including esophageal adenocarcinoma, gastric cardia, colon and rectum, liver, gallbladder, pancreas, meningioma, postmenopausal breast, endometrium, ovary, kidney, thyroid, and multiple myeloma. Given that these cancers account for approximately 40% of all cancers and the high prevalence of overweight or obesity in the US population, maintaining a healthy body weight throughout life is crucial for cancer prevention.
SURGERY FOR OBESITY AND RELATED DISEASES
(2023)
Article
Oncology
Laura Cortesi, Giulia Raffaella Galli, Federica Domati, Luana Conte, Luigi Manca, Maria Antonietta Berio, Angela Toss, Anna Iannone, Massimo Federico
Summary: This study compared the relationship between BMI and breast cancer characteristics in patients from Northern and Southern Italy. The findings revealed a higher rate of overweight and obesity in breast cancer patients from Southern Italy, particularly in those aged 70 years and older, where higher BMI was associated with larger tumor size.
FRONTIERS IN ONCOLOGY
(2021)
Article
Multidisciplinary Sciences
Ka Ying Bonnie Ng, George Cherian, Alexandra J. Kermack, Sarah Bailey, Nick Macklon, Sesh K. Sunkara, Ying Cheong
Summary: Lifestyle factors like being underweight and having BMI>25 significantly contribute to increased risk of RPL in the general population, and BMI>30 and BMI>25 also increase the odds of further miscarriages in women with RPL. However, the quality of evidence for these findings is low. Larger studies focusing on alcohol, cigarette smoking, and caffeine intake effects on RPL risk with BMI optimization are now needed.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Mathias Rask-Andersen, Emma Ivansson, Julia Hoglund Glund, Weronica E. Ek, Torgny Karlsson, Asa Johansson
Summary: Obesity is linked to various types of cancer, and the distribution of fat, which varies between sexes, has been suggested to be an independent risk factor. However, there is limited research on the sex-specific effects on cancer risk. In this study, we examined the effects of fat accumulation and distribution on cancer risk in both females and males. Our findings showed that adiposity traits were associated with most cancer types, and fat accumulation had a greater association with cancer compared to fat distribution. Additionally, the effects of fat accumulation or distribution on colorectal, esophageal, and liver cancer differed between sexes.
Article
Geriatrics & Gerontology
David H. Lynch, Annie Green Howard, Hsiao-Chuan Tien, Shufa Du, Bing Zhang, Huijun Wang, Penny Gordon-Larsen, John A. Batsis
Summary: This study examined the association between weight status and trajectory of cognitive decline in older adults in China. The results showed that weight status was related to the rate of global cognitive decline, with slower decline observed in individuals classified as having obesity.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Erik Stenberg, Gustaf Bruze, Johan Sundstrom, Claude Marcus, Ingmar Naslund, Johan Ottosson, Martin Neovius
Summary: Compared with intensive nonoperative obesity treatment, sleeve gastrectomy in patients with class 1 obesity was associated with greater weight loss, diabetes prevention, and diabetes remission but a higher incidence of substance use disorder and self-harm.
Review
Food Science & Technology
Chandana Deekshith, Markandeya Jois, Jessica Radcliffe, Jency Thomas
Summary: This article systematically reviewed literature on the effects of culinary herbs and spices on obesity in adults, finding eight herbs/spices to be beneficial in regards to obesity, with significant improvements in BMI, weight, and waist circumference.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Review
Endocrinology & Metabolism
Sandra C. Naaman, Sherry Shen, Meltem Zeytinoglu, Neil M. Iyengar
Summary: Obesity is associated with an increased risk of postmenopausal, hormone receptor-positive breast cancer. Factors such as altered adipokine balance and chronic inflammation contribute to tumorigenesis.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Nutrition & Dietetics
Yiding Li, Chenhan Li, Guiling Wu, Wanli Yang, Xiaoqian Wang, Lili Duan, Liaoran Niu, Junfeng Chen, Yujie Zhang, Wei Zhou, Jinqiang Liu, Liu Hong, Daiming Fan
Summary: This systematic review and meta-analysis found that higher BMI is associated with reduced mortality and better outcomes in colorectal cancer patients, contradicting the established understanding of obesity as a risk factor for the disease.
Article
Endocrinology & Metabolism
Waleska Maria Almeida Barros, Karollainy Gomes da Silva, Roberta Karlize Pereira Silva, Ana Patricia da Silva Souza, Ana Beatriz Januario da Silva, Mariluce Rodrigues Marques Silva, Matheus Santos de Sousa Fernandes, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souza
Summary: Childhood obesity is a serious public health problem associated with coordination deficit disorder and impaired motor performance.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Psychology, Multidisciplinary
Nada M. Albawardi, Abeer A. AlTamimi, Mezna A. AlMarzooqi, Lama Alrasheed, Hazzaa M. Al-Hazzaa
Summary: The study found that the majority of Saudi women attending fitness centers in Riyadh were dissatisfied with their body shape, even those with a normal weight. Body dissatisfaction was associated with higher BMI, shorter membership duration at the fitness club, and reduced dairy products and energy drinks consumption among other factors.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Nutrition & Dietetics
Moustapha Drame, Lidvine Godaert
Summary: The obesity paradox refers to the counterintuitive finding that older adults who are overweight or obese may have better outcomes in certain diseases compared to those with normal weight or underweight. This systematic review aims to summarize publications on the obesity paradox in older adults and gain a deeper understanding of this phenomenon.
Review
Endocrinology & Metabolism
Liana Okudzhava, Marcus Heldmann, Thomas F. Muente
Summary: Obesity is associated with alterations in brain white matter microstructure, as shown in diffusion tensor imaging studies. While most studies report decreased fractional anisotropy and increased mean diffusivity in obese individuals, the pattern of alterations is inconsistent. Direct assessment of body fat is recommended for a more accurate understanding of the brain-body relationship.
Review
Nutrition & Dietetics
Azizah Ugusman, Syarifah Amirah Syed Shahrin, Nurul Hana Azizan, Siva Balan Pillai, Khamini Krishnan, Norizam Salamt, Amilia Aminuddin, Adila A. Hamid, Jaya Kumar, Mohd Helmy Mokhtar
Summary: The study systematically reviewed the effects of honey on obesity, finding that honey showed anti-obesity effects in animal studies but had conflicting results in clinical trials. While honey supplementation did not show significant weight reduction in some trials, there was also no evidence that it increased body weight.
FRONTIERS IN NUTRITION
(2022)
Review
Public, Environmental & Occupational Health
Marko Mandic, Hengjing Li, Fatemeh Safizadeh, Tobias Niedermaier, Michael Hoffmeister, Hermann Brenner
Summary: This study aimed to assess if and to what extent potential bias from prediagnostic weight loss has been considered in available epidemiological evidence on the BMI-CRC association. After searching for systematic reviews and meta-analyses, it was found that none of them thoroughly considered or discussed prediagnostic weight loss as a potential source of bias. Results from individual cohort studies included in the latest review were reported heterogeneously, but effect estimates mostly increased with increasing length of exclusion of initial years of follow-up. The impact of overweight and obesity on CRC risk may be larger than suggested by the existing epidemiological evidence.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)