Wogonin-enhanced reactive oxygen species-induced apoptosis and potentiated cytotoxic effects of chemotherapeutic agents by suppression Nrf2-mediated signaling in HepG2 cells

Wogonin induces apoptosis by activating the AMPK and p53 signaling pathways in human glioblastoma cells

(2012) Dae-Hee Lee et al.   CELLULAR SIGNALLING

Wogonin Induces Reactive Oxygen Species Production and Cell Apoptosis in Human Glioma Cancer Cells

(2012) Cheng-Fang Tsai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Enhanced sensitivity of A549 cells to the cytotoxic action of anticancer drugs via suppression of Nrf2 by procyanidins from Cinnamomi Cortex extract

(2011) Tomokazu Ohnuma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates

(2011) Constance Lay-Lay Saw et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Keap1 Mutations and Nrf2 Pathway Activation in Epithelial Ovarian Cancer

(2011) P. A. Konstantinopoulos et al.   CANCER RESEARCH

p53 and c-myc: How does the cell balance “yin” and “yang”?

(2011) Mohit Sachdeva et al.   CELL CYCLE

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress

(2011) A. T. Shaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling Functions of Reactive Oxygen Species

(2010) Henry Jay Forman et al.   BIOCHEMISTRY

C-Myc is a Nrf2-interacting protein that negatively regulates phase II genes through their electrophile responsive elements

(2010) Smadar Levy et al.   IUBMB LIFE

Different apoptotic effects of wogonin via induction of H2O2 generation and Ca2+ overload in malignant hepatoma and normal hepatic cells

(2010) Libin Wei et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

ABCG2: A potential marker of stem cells and novel target in stem cell and cancer therapy

(2010) Xi-wei Ding et al.   LIFE SCIENCES

Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

(2010) P. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells

(2009) Sheng-Teng Huang et al.   PHYTOMEDICINE

Nrf2 signaling and cell survival

(2009) Suryakant K. Niture et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin

(2007) Hak-Ryul Kim et al.   LUNG CANCER