Free radical oxidation of cardiolipin: chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases

Isoprostane Generation and Function

(2011) Ginger L. Milne et al.   CHEMICAL REVIEWS

Free Radical Lipid Peroxidation: Mechanisms and Analysis

(2011) Huiyong Yin et al.   CHEMICAL REVIEWS

Fragmentation of mitochondrial cardiolipin by copper ions in the Atp7b−/− mouse model of Wilson's disease

(2011) Irina L. Yurkova et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Permeabilization of the Mitochondrial Outer Membrane by Bax/Truncated Bid (tBid) Proteins as Sensitized by Cardiolipin Hydroperoxide Translocation

(2011) Witold Korytowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin

(2011) Giuseppe Paradies et al.   NEUROCHEMISTRY INTERNATIONAL

The complexity of cardiolipin in health and disease

(2011) Steven M. Claypool et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Strategy for Suppressing Redox Stress within Mitochondria

(2011) Pablo M. Arce et al.   ACS Medicinal Chemistry Letters

A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death

(2011) Jeffrey Atkinson et al.   Nature Communications

Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling

(2010) Pankaj Chaudhary et al.   BIOCHEMISTRY

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

(2010) Joan Montero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Apoptosis-induced changes in mitochondrial lipids

(2010) Massimo Crimi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ex Vivo Oxidation in Tissue and Plasma Assays of Hydroxyoctadecadienoates:Z,E/E,EStereoisomer Ratios

(2010) Wei Liu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Protection of Pancreatic β-Cells by Group VIA Phospholipase A2-Mediated Repair of Mitochondrial Membrane Peroxidation

(2010) Zhengshan Zhao et al.   ENDOCRINOLOGY

Photosensitization of intact heart mitochondria by the phthalocyanine Pc 4: Correlation of structural and functional deficits with cytochrome c release

(2010) Junhwan Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Photo-oxidation of cardiolipin and cytochrome c with bilayer-embedded Pc 4

(2010) Junhwan Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decomposition

(2010) Wei Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardiolipin and oxidative stress: Identification of new short chain oxidation products of cardiolipin in in vitro analysis and in nephrotoxic drug-induced disturbances in rat kidney tissue

(2010) Elisabete Maciel et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Chronic Alcohol Exposure Increases Circulating Bioactive Oxidized Phospholipids

(2010) Lili Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipids, Mitochondria and Cell Death: Implications in Neuro-oncology

(2010) Alison Colquhoun   MOLECULAR NEUROBIOLOGY

Mechanistic Issues of the Interaction of the Hairpin-Forming Domain of tBid with Mitochondrial Cardiolipin

(2010) François Gonzalvez et al.   PLoS One

Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia

(2010) R. P. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liquid chromatography/tandem mass spectrometry analysis of long-chain oxidation products of cardiolipin induced by the hydroxyl radical

(2010) Elisabete Maciel et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease

(2010) F. D. Porter et al.   Science Translational Medicine

Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions☆

(2009) Valerian E. Kagan et al.   ADVANCED DRUG DELIVERY REVIEWS

Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis

(2009) Zachary T. Schug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease

(2009) Giuseppe Paradies et al.   CELL CALCIUM

Oxidizability of cardiac cardiolipin in Triton X-100 micelles as determined by using a Clark electrode

(2009) Vitaly Roginsky   CHEMISTRY AND PHYSICS OF LIPIDS

Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO and protects mouse embryonic cells against irradiation-induced apoptosis

(2009) Natalia A. Belikova et al.   FEBS LETTERS

Cytochrome c/cardiolipin relations in mitochondria: a kiss of death

(2009) Valerian E. Kagan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of hepatic mitochondrial aldehyde dehydrogenase by carbon tetrachloride through JNK-mediated phosphorylation

(2009) Kwan-Hoon Moon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Peroxidase Mechanism of Lipid-dependent Cross-linking of Synuclein with Cytochromec

(2009) Hülya Bayır et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins

(2009) Aaron T. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterolytic Reduction of Fatty Acid Hydroperoxides by Cytochromec/Cardiolipin Complexes: Antioxidant Function in Mitochondria

(2009) Natalia A. Belikova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitochondrial gateways to cancer

(2009) Lorenzo Galluzzi et al.   MOLECULAR ASPECTS OF MEDICINE

Elevated levels of hydroxylated phosphocholine lipids in the blood serum of breast cancer patients

(2009) Loubna A. Hammad et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling

Targeting Mitochondria

(2008) Adam T. Hoye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target?

(2008) Simon Pope et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Cardiolipin, the heart of mitochondrial metabolism

(2008) R. H. Houtkooper et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intermolecular Peroxyl Radical Reactions during Autoxidation of Hydroxy and Hydroperoxy Arachidonic Acids Generate a Novel Series of Epoxidized Products

(2008) Claus Schneider et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mass spectrometry analysis of oxidized phospholipids

(2008) M. Rosário M. Domingues et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation

(2008) Claus Schneider et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis

(2008) Vladimir A. Tyurin et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondria-targeted disruptors and inhibitors of cytochromec/cardiolipin peroxidase complexes: A new strategy in anti-apoptotic drug discovery

(2008) Valerian E. Kagan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria

(2007) Qun Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Oxidative lipidomics of γ-irradiation-induced intestinal injury

(2007) Yulia Y. Tyurina et al.   FREE RADICAL BIOLOGY AND MEDICINE