The tyrphostin AG1478 augments oridonin-induced A431 cell apoptosis by blockage of JNK MAPK and enhancement of oxidative stress

Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells

(2011) Simiao Fan et al.   FREE RADICAL RESEARCH

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

(2011) Lakshmi Raj et al.   NATURE

The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression

(2011) Daniel Schramek et al.   NATURE GENETICS

Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways

(2010) Ning Kang et al.   CANCER LETTERS

Oridonin induces G2/M arrest and apoptosis via activating ERK–p53 apoptotic pathway and inhibiting PTK–Ras–Raf–JNK survival pathway in murine fibrosarcoma L929 cells

(2009) Yan Cheng et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells

(2009) Yan Cheng et al.   Autophagy

Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy

(2009) Isamu Okamoto   FEBS Journal

Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer

(2009) Seong Soo Joo et al.   JOURNAL OF PINEAL RESEARCH

Recent Developments in Anti-Cancer Agents Targeting the Ras/Raf/ MEK/ERK Pathway

(2009) Kwong-Kwok Wong   Recent Patents on Anti-Cancer Drug Discovery

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease

Fas-mediated autophagy requires JNK activation in HeLa cells

(2008) Yahong Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reactive Oxygen Species Mediate Oridonin-Induced HepG2 Apoptosis Through p53, MAPK, and Mitochondrial Signaling Pathways

(2008) Jian Huang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE

Oridonin induces human epidermoid carcinoma A431 cell apoptosis through tyrosine kinase and mitochondrial pathway

(2007) DAN Li et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH