Journal
FREE RADICAL RESEARCH
Volume 44, Issue 3, Pages 332-339Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/10715760903494184
Keywords
Selenite; antioxidant enzyme; siRNA; redox status
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Selenium has been shown to play a chemopreventive role in human cancer, presumably by inducing tumour cell apoptosis. Selenite is thought to induce oxidative stress by the generation of the superoxide anion and catalysing the oxidation of thiol groups. It has previously been reported that control of the mitochondrial redox balance is a primary function of mitochon-drial NADP
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