Article
Biochemical Research Methods
Younis Abiedalla, C. Randall Clark
Summary: The electron ionization (EI)-mass spectroscopy (MS) fragmentation of methoxymethylene substituted benzoate esters was studied. The aliphatic oxygen of the alkoxymethylene group plays a more active role in the fragmentation profile compared to the direct aromatic ring linked oxygen of the ethoxy group.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Younis Abiedalla, Ahmad J. Almalki, Jack DeRuiter, C. Randall Clark
Summary: This study prepared and evaluated twelve secondary amines representing structural analogues of the classic NBOMe category of novel psychoactive substances. The compounds were compared in terms of GC properties and correlated EI-MS fragmentation products, providing differentiation data from the current NBOMe drugs of abuse.
FORENSIC CHEMISTRY
(2021)
Article
Chemistry, Analytical
Younis Abiedalla, Ahmad J. Almalki, Jack DeRuiter, C. Randall Clark
Summary: The study describes a potential category of novel psychoactive substances synthesized via a specific synthetic pathway. Gas chromatographic separations of different subseries of molecules revealed specific ion fragments in the mass spectra. Vapor phase infrared spectra provided information on the position of substitution of the methoxy groups on the aromatic ring.
FORENSIC CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Shin Morioka, Hiroki Nakanishi, Toshiyoshi Yamamoto, Junya Hasegawa, Emi Tokuda, Tomoya Hikita, Tomoko Sakihara, Yuuki Kugii, Chitose Oneyama, Masakazu Yamazaki, Akira Suzuki, Junko Sasaki, Takehiko Sasaki
Summary: A new method called PRMC-MS has been developed to analyze the dynamics of phosphoinositide acyl variants. The study reveals specific changes in acyl chains in prostate cancer tissues with PTEN deficiency and upon expression of oncogenic PIK3CA.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Applied
Bing Lyu, Xiaoyan Zhang, Jingguang Li, Lei Zhang, Yuxin Zhong, Yongning Wu
Summary: The present study evaluated two GC-MS/MS instruments with different ion sources for detecting trace levels of PCDD/Fs in various foods. The GC-MS/MS methods showed good sensitivity, repeatability, and reproducibility, and the results were comparable to those obtained with GC-HRMS.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Chao Han, Chaoqun Huang, Qinting Jiang, Li Chen, Yi Li, Chengjie Lou, Hailing Lu, Yan Shen
Summary: A novel and accurate method for the determination of folpet and phthalimide residues in tea has been developed, using solid-phase extraction combined with gas chromatography-tandem mass spectrometry. The method proposes converting all folpet to phthalimide prior to sample extraction and purification, and utilizes an isotopic internal standard for quantification. The study confirms the accurate determination of phthalimide content and its conversion to folpet content.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Applied
Mu Zhao, Ting Li, Fan Yang, Xinyue Cui, Tingting Zou, Huanlu Song, Ye Liu
Summary: This study characterized the composition of volatile aroma compounds and key aroma-active compounds in dried Hanyuan Zanthoxylum bungeanum. The results identified several key aroma-active compounds such as myrcene and limonene.
Article
Chemistry, Applied
Xuejie Li, Xiangquan Zeng, Huanlu Song, Yu Xi, Yan Li, Bowen Hui, He Li, Jian Li
Summary: GC x GC-O-TOF-MS and GC-IMS have been increasingly used in complex food flavor analysis, but few studies have applied these techniques to identify the aroma components of tomato pastes. This study comprehensively characterized the aroma profiles of cold and hot break tomato pastes using SAFE-GC-O-MS, SAFE-GC x GC-O-TOF-MS, and HS-GC-IMS for the first time. A total of 274 volatile compounds were identified, which is far more than previously reported.
Article
Chemistry, Applied
Yanqin Yang, Jialing Xie, Qiwei Wang, Yuliang Deng, Li Zhu, Jiayi Zhu, Haibo Yuan, Yongwen Jiang
Summary: This study comprehensively characterized the volatile and non-volatile compounds during black tea processing using volatolomics and UHPLC-Q-Exactive/MS analysis. The results showed that these metabolites changed continuously throughout the processing process, with significant changes during the withering stage. A total of 178 volatile metabolites and 103 non-volatile metabolites were identified, and 11 volatile components were identified as key aroma active components responsible for sweet aroma in finished black tea.
Article
Energy & Fuels
Luise Carvalho Dias, Karina Santos Garcia, Antonio Fernando de Souza Queiroz, Maria Elisabete Machado
Summary: This study presents and validates a novel GC-MS/MS method for the determination of nitrogen-containing heterocyclic aromatic compounds in crude oils, showcasing its potential for fast, easy, and efficient quantitative analysis of N-markers.
Article
Chemistry, Analytical
Jennifer K. Field, Christine Hinz, Christopher M. Titman, Matthew C. Hulme, Rhona M. Cowan, Jack B. Ainsworth-McMillan, Nicolas Gilbert, Robert J. Lee, Jack Marron, Andrew Costello, Ryan E. Mewis, Melvin R. Euerby, Oliver B. Sutcliffe
Summary: This study presents the development of a rapid gradient UHPLC method with targeted MS/MS for the detection and confirmation of the identity of 33 substituted diphenidine derivatives in solid drug samples. The study also investigates the influence of substituents on the elution order and the retention mechanism of diphenidines under reverse-phase UHPLC conditions. The developed method was proven to be specific through the assessment of common adulterants, and it was successfully applied to confirm the identity of psychoactive components in seized bulk samples.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Food Science & Technology
Chao Han, Beizhen Hu, Chaoqun Huang, Wenhua Zhang, Huizhen Wu, Caiqin Liu, Qiyong Chen, Yan Shen
Summary: A new analytical method involving gas chromatography-tandem mass spectrometry (GC-MS/MS) was developed for the determination of morpholine residues in fruit and fruit juice samples. The method showed good precision and accuracy and can be widely applied in food safety monitoring.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Environmental Sciences
Zi-Feng Zhang, Jia-Cheng Chen, Ya-Xian Zhao, Lu Wang, Yu-Qian Teng, Ming-Hong Cai, Yan-Hui Zhao, Anatoly Nikolaev, Yi-Fan Li
Summary: Polycyclic aromatic hydrocarbons (PAHs) are toxic organic pollutants that have been widely detected in various regions and environmental matrices. However, not all PAHs are usually detected, and there is no established method to systematically analyze hundreds of PAHs. In this study, a gas chromatography-tandem triple-quadrupole mass spectrometry (GC-MS/MS) method was developed and successfully applied to identify and quantify 123 PAHs in marine samples.
Article
Multidisciplinary Sciences
Lubna Rahman, Asma Mukhtar, Sajjad Ahmad, Lutfur Rahman, Muhammad Ali, Muhammad Saeed, Zabta Khan Shinwari
Summary: The current study aimed to isolate and identify bioactive compounds from endophytic bacteria. Molecular docking and biological assays were used to investigate the interactions between the compounds and bacterial cells. The study discovered antibacterial compounds and provided important information on drug-receptor interactions, which can be useful in novel drug discovery.
Article
Chemistry, Applied
Fabio Xavier Antunes Sampaio, Karina Santos Garcia, Antonio Fernando de Souza Queiroz, Maria Elisabete Machado
Summary: Organic sulfur compounds in crude oils are important geochemical markers for maturity, lithology, and biodegradation. This study developed a gas chromatography-triple quadrupole mass spectrometry method for the determination of 14 organic sulfur compounds without preliminary fractionation, providing a precise and accurate analytical strategy.
FUEL PROCESSING TECHNOLOGY
(2021)
Article
Chemistry, Analytical
H. M. Maher, N. Z. Alzoman, S. M. Shehata
Article
Biochemical Research Methods
Hadir M. Maher, Nourah Z. Alzoman, Shereen M. Shehata, Ashwag O. Abahussain
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2017)
Article
Chemistry, Analytical
Hadir M. Maher, Nourah Z. Alzoman, Shereen M. Shehata, Ashwag O. Abahussain
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2017)
Article
Biochemical Research Methods
Nourah Zoman Alzoman, Hadir Mohamed Maher, Hessa Ai-Showiman, Ghada Ahmed Fawzy, Areej Mohammad Ai-Taweel, Shagufta Perveen, Rasool Bakhsh Tareen, Ruba Mahmoud Ai-Sabbagh
JOURNAL OF CHROMATOGRAPHIC SCIENCE
(2018)
Article
Multidisciplinary Sciences
Hadir M. Maher, Nourah Z. Alzoman, Shereen M. Shehata, Norah O. Abanmy
Article
Pharmacology & Pharmacy
Haya Aljohar, Hadir M. Maher, Jawza Albaqami, Maha Al-Mehaizie, Rawan Orfali, Razan Orfali, Sarah Alrubia
SAUDI PHARMACEUTICAL JOURNAL
(2018)
Article
Biochemical Research Methods
Hadir M. Maher, Nourah Z. Alzoman, Shereen M. Shehata
Article
Chemistry, Multidisciplinary
Hadir M. Maher, Nourah Z. Alzoman, Munira Abdulaziz Almeshal, Hawazin Abdullah Alotaibi, Njoud Naif Alotaibi, Hessa Al-Showiman
ARABIAN JOURNAL OF CHEMISTRY
(2020)
Article
Biochemical Research Methods
Nourah Zoman Al-Zoman, Hadir Mohamed Maher, Amal Al-Subaie
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
(2018)
Article
Biochemical Research Methods
Hadir M. Maher, Afnan E. Abdelrahman, Nourah Z. Alzoman, Haya I. Aljohar
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
(2019)
Article
Biochemical Research Methods
Haya Aljohar, Sarah N. Abuhaimed, Hadir M. Maher, Bader A. Nafisan, Abdullah M. Alkhalaf
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
(2019)
Article
Biochemical Research Methods
Nourah Z. Alzoman, Hadir M. Maher, Shereen M. Shehata, Norah O. Abanmy
BIOMEDICAL CHROMATOGRAPHY
(2019)
Article
Biotechnology & Applied Microbiology
Hadir M. Maher, Aliyah Almomen, Nourah Z. Alzoman, Shereen M. Shehata, Amal Al-Subaie
BIOMED RESEARCH INTERNATIONAL
(2019)
Article
Chemistry, Analytical
Haya I. Al-Johar, Hadir M. Maher, Nourah Z. Al-Zoman, Dlayel J. Al-Shammary, Hessa Al-Showiman
ACTA CHROMATOGRAPHICA
(2017)
Article
Chemistry, Multidisciplinary
Nourah Zoman Al-Zoman, Hadir Mohamed Maher, Amal Al-Subaie
CHEMISTRY CENTRAL JOURNAL
(2017)
Article
Medicine, Legal
Heitor S. D. Correa, Ivano Alessandri, Andrea Verzeletti
Summary: This research assessed the usefulness of Raman spectroscopy and gas chromatography-mass spectrometry in analyzing bones. The techniques were found to be useful in molecular taphonomy studies and forensic genetics.
FORENSIC SCIENCE INTERNATIONAL
(2024)