Investigating cell mechanics with atomic force microscopy

Auxetic nuclei in embryonic stem cells exiting pluripotency

(2014) Stefano Pagliara et al.   NATURE MATERIALS

A FAK-Cas-Rac-Lamellipodin Signaling Module Transduces Extracellular Matrix Stiffness into Mechanosensitive Cell Cycling

(2014) Y. H. Bae et al.   Science Signaling

Monitoring Actin Cortex Thickness in Live Cells

(2013) Andrew G. Clark et al.   BIOPHYSICAL JOURNAL

Actin and microtubules play distinct roles in governing the anisotropic deformation of cell nuclei in response to substrate strain

(2013) Dominique Tremblay et al.   Cytoskeleton

Resiliency of the plasma membrane and actin cortex to large-scale deformation

(2013) Kristina Haase et al.   Cytoskeleton

Wedged AFM-cantilevers for parallel plate cell mechanics

(2013) Martin P. Stewart et al.   METHODS

The cytoplasm of living cells behaves as a poroelastic material

(2013) Emad Moeendarbary et al.   NATURE MATERIALS

Cross talk between matrix elasticity and mechanical force regulates myoblast traction dynamics

(2013) Zeinab Al-Rekabi et al.   PHYSICAL BIOLOGY

Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces

(2013) A. F. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds

(2013) C.-y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force-Induced Changes in Subnuclear Movement and Rheology

(2012) Elizabeth A. Booth-Gauthier et al.   BIOPHYSICAL JOURNAL

Actin filaments play a primary role for structural integrity and viscoelastic response in cells

(2012) Alperen N. Ketene et al.   Integrative Biology

Force transduction and strain dynamics in actin stress fibres in response to nanonewton forces

(2012) L. Guolla et al.   JOURNAL OF CELL SCIENCE

Determination of the elastic moduli of thin samples and adherent cells using conical atomic force microscope tips

(2012) Núria Gavara et al.   Nature Nanotechnology

Tracking mechanics and volume of globular cells with atomic force microscopy using a constant-height clamp

(2012) Martin P Stewart et al.   Nature Protocols

Resolving the Stiffening-Softening Paradox in Cell Mechanics

(2012) Lars Wolff et al.   PLoS One

Cell Visco-Elasticity Measured with AFM and Optical Trapping at Sub-Micrometer Deformations

(2012) Schanila Nawaz et al.   PLoS One

Viscoelastic Cell Mechanics and Actin Remodelling Are Dependent on the Rate of Applied Pressure

(2012) Priyanka Pravincumar et al.   PLoS One

Active contractility in actomyosin networks

(2012) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular mechanical properties reflect the differentiation potential of adipose-derived mesenchymal stem cells

(2012) R. D. Gonzalez-Cruz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterizing the mechanics of cultured cell monolayers

(2012) A. R. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubules Underlie Dysfunction in Duchenne Muscular Dystrophy

(2012) R. J. Khairallah et al.   Science Signaling

Actin cortex mechanics and cellular morphogenesis

(2012) Guillaume Salbreux et al.   TRENDS IN CELL BIOLOGY

Use the force: membrane tension as an organizer of cell shape and motility

(2012) Alba Diz-Muñoz et al.   TRENDS IN CELL BIOLOGY

Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells

(2012) Yeh-Chuin Poh et al.   Nature Communications

Linear and Nonlinear Rheology of Living Cells

(2011) Philip Kollmannsberger et al.   Annual Review of Materials Research

Cancer cell detection in tissue sections using AFM

(2011) Małgorzata Lekka et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Direct Detection of Cellular Adaptation to Local Cyclic Stretching at the Single Cell Level by Atomic Force Microscopy

(2011) Takahiro Watanabe-Nakayama et al.   BIOPHYSICAL JOURNAL

Reconstitution of Contractile Actomyosin Bundles

(2011) Todd Thoresen et al.   BIOPHYSICAL JOURNAL

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Generic phases of cross-linked active gels: Relaxation, oscillation and contractility

(2011) S. Banerjee et al.   EPL

Characterization of cell elasticity correlated with cell morphology by atomic force microscope

(2011) Qiuquan Guo et al.   JOURNAL OF BIOMECHANICS

Dependence of cyclic stretch-induced stress fiber reorientation on stretch waveform

(2011) Abhishek Tondon et al.   JOURNAL OF BIOMECHANICS

Nucleoskeleton mechanics at a glance

(2011) K. N. Dahl et al.   JOURNAL OF CELL SCIENCE

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

(2011) P. P. Provenzano et al.   JOURNAL OF CELL SCIENCE

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Collective cell guidance by cooperative intercellular forces

(2011) Dhananjay T. Tambe et al.   NATURE MATERIALS

Mapping nanomechanical properties of live cells using multi-harmonic atomic force microscopy

(2011) A. Raman et al.   Nature Nanotechnology

Single-molecule recognition force spectroscopy of transmembrane transporters on living cells

(2011) Theeraporn Puntheeranurak et al.   Nature Protocols

Moving into the cell: single-molecule studies of molecular motors in complex environments

(2011) Claudia Veigel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

(2011) Patrick Delmas et al.   NATURE REVIEWS NEUROSCIENCE

High-resolution atomic force microscopy and spectroscopy of native membrane proteins

(2011) Christian A Bippes et al.   REPORTS ON PROGRESS IN PHYSICS

Biomechanical regulation of contractility: spatial control and dynamics

(2011) Romain Levayer et al.   TRENDS IN CELL BIOLOGY

Stretch magnitude and frequency-dependent actin cytoskeleton remodeling in alveolar epithelia

(2010) Brian C. DiPaolo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Using indentation to characterize the poroelasticity of gels

(2010) Yuhang Hu et al.   APPLIED PHYSICS LETTERS

Cyclic stretch-induced stress fiber dynamics – Dependence on strain rate, Rho-kinase and MLCK

(2010) Chin-Fu Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Force propagation and force generation in cells

(2010) Oliver Jonas et al.   Cytoskeleton

Molecular imaging of membrane proteins and microfilaments using atomic force microscopy

(2010) Se-Hui Jung et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?

(2010) A. Buxboim et al.   JOURNAL OF CELL SCIENCE

The primary cilium at a glance

(2010) P. Satir et al.   JOURNAL OF CELL SCIENCE

Mechanisms of mechanical signaling in development and disease

(2010) P. A. Janmey et al.   JOURNAL OF CELL SCIENCE

Emergence of a prestressed eukaryotic nucleus during cellular differentiation and development

(2010) A. Mazumder et al.   Journal of the Royal Society Interface

Atomic force microscopy: probing the spatial organization, interactions and elasticity of microbial cell envelopes at molecular resolution

(2010) Simon Scheuring et al.   MOLECULAR MICROBIOLOGY

Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding

(2010) Martin P. Stewart et al.   NATURE

Regulation of the Actin Cytoskeleton-Plasma Membrane Interplay by Phosphoinositides

(2010) Juha Saarikangas et al.   PHYSIOLOGICAL REVIEWS

Stretch-Activated Ion Channels: What Are They?

(2010) Frederick Sachs   PHYSIOLOGY

Fluidization and Resolidification of the Human Bladder Smooth Muscle Cell in Response to Transient Stretch

(2010) Cheng Chen et al.   PLoS One

Coordinating mitosis with cell polarity: Molecular motors at the cell cortex

(2010) Jeffrey K. Moore et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Control of Directed Cell Migration In Vivo by Membrane-to-Cortex Attachment

(2010) Alba Diz-Muñoz et al.   PLOS BIOLOGY

Cell Mechanics: Dissecting the Physical Responses of Cells to Force

(2009) Brenton D. Hoffman et al.   Annual Review of Biomedical Engineering

Detection of erythrocytes influenced by aging and type 2 diabetes using atomic force microscope

(2009) Hua Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Animal cell hydraulics

(2009) G. T. Charras et al.   JOURNAL OF CELL SCIENCE

Intracellular fluid flow in rapidly moving cells

(2009) Kinneret Keren et al.   NATURE CELL BIOLOGY

Combined atomic force microscopy and side-view optical imaging for mechanical studies of cells

(2009) Ovijit Chaudhuri et al.   NATURE METHODS

Atomic force microscopy detects differences in the surface brush of normal and cancerous cells

(2009) S. Iyer et al.   Nature Nanotechnology

Reinforcement versus Fluidization in Cytoskeletal Mechanoresponsiveness

(2009) Ramaswamy Krishnan et al.   PLoS One

Active soft glassy rheology of adherent cells

(2009) Philip Kollmannsberger et al.   Soft Matter

Mechanical dynamics of single cells during early apoptosis

(2009) Andrew E. Pelling et al.   CELL MOTILITY AND THE CYTOSKELETON

Active Biological Materials

(2008) Daniel A. Fletcher et al.   Annual Review of Physical Chemistry

AFM indentation study of breast cancer cells

(2008) Q.S. Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell-Cell Mechanical Communication through Compliant Substrates

(2008) Cynthia A. Reinhart-King et al.   BIOPHYSICAL JOURNAL

Two Characteristic Regimes in Frequency-Dependent Dynamic Reorientation of Fibroblasts on Cyclically Stretched Substrates

(2008) Simon Jungbauer et al.   BIOPHYSICAL JOURNAL

Nuclear Shape, Mechanics, and Mechanotransduction

(2008) Kris Noel Dahl et al.   CIRCULATION RESEARCH

Moesin Controls Cortical Rigidity, Cell Rounding, and Spindle Morphogenesis during Mitosis

(2008) Patricia Kunda et al.   CURRENT BIOLOGY

Intermediate filaments: versatile building blocks of cell structure

(2008) Robert D Goldman et al.   CURRENT OPINION IN CELL BIOLOGY

Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation

(2008) Nan Xia et al.   FASEB JOURNAL

Focal Adhesion Kinase Is Important for Fluid Shear Stress–Induced Mechanotransduction in Osteoblasts

(2008) Suzanne RL Young et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanotransduction - a field pulling together?

(2008) C. S. Chen   JOURNAL OF CELL SCIENCE

Mechanical properties of plasma membrane and nuclear envelope measured by scanning probe microscope

(2008) M. YOKOKAWA et al.   JOURNAL OF MICROSCOPY

Mitochondrial displacements in response to nanomechanical forces

(2008) Yaron R. Silberberg et al.   JOURNAL OF MOLECULAR RECOGNITION

Fluctuations of intracellular forces during cell protrusion

(2008) Lin Ji et al.   NATURE CELL BIOLOGY

Mechanotransduction in development: a growing role for contractility

(2008) Michele A. Wozniak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Limits of Filopodium Stability

(2008) Sander Pronk et al.   PHYSICAL REVIEW LETTERS

Correction for Malone et al., Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism

(2008)   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes

(2007) Eric M. Darling et al.   JOURNAL OF BIOMECHANICS