Article
Multidisciplinary Sciences
Lingming Zhang, Chao Zheng, Tongdao Xu, Liang Du
Summary: This study evaluated the antidiabetic activities of aqueous extracts of Eclipta prostrata L. in streptozotocin (STZ)-induced diabetic rats. The results showed that the extracts improved carbohydrate metabolizing enzyme function, reduced total cholesterol, increased serum HDL cholesterol levels, and exhibited antioxidant activities.
Article
Biochemistry & Molecular Biology
Muhammad Khan, Muhammad Ajmal Shah, Mustafa Kamal, Mohammad Shamsul Ola, Mehboob Ali, Pharkphoom Panichayupakaranant
Summary: The combination of LME and lawsone from Impatiens balsamina effectively reduces blood glucose, insulin, and lipid levels in diabetic rats, without causing toxicity.
Article
Nutrition & Dietetics
Maha N. Abu Hajleh, Khaled M. Khleifat, Moath Alqaraleh, Esra'a Al-Hraishat, Muhamad O. Al-limoun, Haitham Qaralleh, Emad A. S. Al-Dujaili
Summary: The aqueous extract of Ephedra foeminea shows promising antidiabetic properties in streptozotocin-induced diabetic rats, with significant improvements in blood glucose levels, lipid profile, and liver and kidney functions. The extract also exhibits antioxidant activity and may have potential medicinal benefits.
Article
Plant Sciences
Nalluri Vedasree, Kotha Peddanna, Allagadda Rajasekhar, Chinthirla ParthaSarathi, Pasupuleti Munirajeswari, Yallanki Sireesha, Appa Rao Chippada
Summary: This study confirmed the anti-diabetic effects of Cyanotis tuberosa root tubers (CTRT) in diabetic rats by improving insulin secretion, glycemic control, and restoring functional activities of the liver and kidney.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Environmental Sciences
Eman E. Yassien, Moaz M. Hamed, Usama Ramadan Abdelmohsen, Hanaa M. Hassan, Hanaa S. S. Gazwi
Summary: The study focused on the impact of ethanolic Avicennia marina leaves extract against pathogenic bacteria and hyperlipidemia caused by dexamethasone-treated rats. The extract showed high activity against certain bacteria and reversed distorted lipid profile caused by dexamethasone, demonstrating its potential protective and hypolipidemic properties.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Yanping Huang, Tolulope Joshua Ashaolu, Opeyemi Joshua Olatunji
Summary: This study found that micronized okara fiber (MOF) has anti-diabetic effects and improves the secretory functions of pancreatic β cells in a rat model of diabetes mellitus. It could be used as a protective nutrient in diabetes.
Article
Nutrition & Dietetics
Cristina Mesas, Rosario Martinez, Raul Ortiz, Milagros Galisteo, Maria Lopez-Jurado, Laura Cabeza, Gloria Perazzoli, Consolacion Melguizo, Jesus M. Porres, Jose Prados
Summary: The seeds of Euphorbia lathyris contain various polyphenolic bioactive compounds that have demonstrated anti-tumor, antioxidant, and anti-angiogenic activities. The extract shows potential therapeutic effects against colon cancer and further in vivo experiments are needed to validate its efficacy.
Article
Pharmacology & Pharmacy
Arturo Orozco-Barocio, Blanca Susana Robles-Rodriguez, Maria del Rayo Camacho-Corona, Luis Fernando Mendez-Lopez, Marisol Godinez-Rubi, Jorge Peregrina-Sandoval, Gildardo Rivera, Argelia E. Rojas Mayorquin, Daniel Ortuno-Sahagun
Summary: This study found that extracts of L. schottii have cytotoxic effects on cancer cells and splenocytes, with the polar fraction being the most effective. The main secondary metabolites present are flavonoids and alkaloids.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Physiology
Ramachawolran Gobinath, Subramani Parasuraman, Subramaniam Sreeramanan, Balaji Enugutti, Suresh V. Chinni
Summary: This study evaluated the effects of Spondias mombin leaf extract on diabetic rats and found that it exhibited significant antidiabetic and antihyperlipidemic activities.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Ibrahim Al-deeb, Julia Joseph, Amin Malik Shah Abdul Majid, Aman Shah Abdul Majid, Nozlena Abdul Samad
Summary: This study examined the antiangiogenic properties of the ethanolic crude extract from Vernonia amygdalina (VA) grown in Malaysia. The extract demonstrated significant inhibition of cell proliferation, colony formation, migration, and invasion, indicating its potential as a chemotherapeutic and/or chemopreventive agent.
Article
Biochemistry & Molecular Biology
Samah A. El-Newary, Sherif M. Afifi, Mohamed S. Aly, Rania F. Ahmed, Abd El-Nasser G. El Gendy, Ahmed M. Abd-ElGawad, Mohamed A. Farag, Abdelbaset M. Elgamal, Abdelsamed I. Elshamy
Summary: The study demonstrated that the ethanolic extract of Launaea nudicaulis has significant anti-diabetic activity, reducing blood glucose levels and increasing insulin secretion. The extract also prevented weight loss in rats and improved diabetic complications such as liver, kidney, and testis function.
Article
Plant Sciences
Arlette Nguemfo Tchankugni, Mpoame Mbida, Jurgen Hescheler, Filomain Nguemo
Summary: This study aimed to investigate the cardiac effect of Vernonia amygdalina leaf extracts using mouse induced pluripotent stem cells (miPSCs) and their cardiomyocytes' (CMs) derivatives. The ethanolic extract of V. amygdalina showed a concentration-dependent effect on cell proliferation, colony formation, and cardiac beating activity.
Article
Chemistry, Applied
Atia-tul-Wahab, Qibtiya Ilyas, Saba Farooq, Sumaira Javaid, Shakil Ahmed, Atta-ur-Rahman, M. Lqbal Choudharya
Summary: The study evaluated the antifungal activity of Trachyspermum ammi seeds against Candida albicans, showing promising results in both in-vitro and in-vivo experiments. The hexanes fraction had a minimal inhibitory concentration of 225 mu g/mL, and the ointment containing the extract and fraction led to 90-100% recovery in mice with cutaneous candidiasis. GC/MS analysis revealed the presence of major components in the hexanes extract, indicating the potential for development of novel antifungal agents.
NATURAL PRODUCT RESEARCH
(2021)
Article
Multidisciplinary Sciences
Guang-li Bian, Ya-lin Hu, Kai Yan, Xin-jie Cheng, De-qiang Li
Summary: The study found that extracts obtained by modern extraction techniques such as ASE from Vernonia anthelmintica Willd (VA) exhibited high extraction efficiency and antioxidant activity, making them suitable for the food and medical industries. Additionally, all extracts showed effects on key enzymes related to vitiligo and type II diabetes, highlighting their potential for therapeutic bio-product development.
Article
Multidisciplinary Sciences
Fatimoh Idowu Ojuade, Olufunke Esan Olorundare, Olatunde Babatunde Akanbi, Saheed Olanrewaju Afolabi, Anoka Ayembe Njan
Summary: This study demonstrated that Parquetina nigrescens exhibited significant antidiabetic and antihyperlipidemic effects in streptozotocin-nicotinamide-induced type 2 diabetic rats, promoting pancreatic regeneration and improving lipid profiles.
Article
Chemistry, Organic
M. Vijaya Bhaskara Reddy, D. Srinivasulu, K. Peddanna, Ch. Apparao, P. Ramesh
SYNTHETIC COMMUNICATIONS
(2015)
Article
Chemistry, Medicinal
Kuppi Reddy Gari Divya, Donthamsetty V. Sowmya, Suram Durgamma, Vadlamudi Tharanath, Divi Venkataramana Sai Gopal, Malaka Venkateshwarulu Jyothi Kumar, Chippada Appa Rao, Adivireddy Padmaja, Venkatapuram Padmavathi
MEDICINAL CHEMISTRY RESEARCH
(2017)
Article
Chemistry, Inorganic & Nuclear
S. K. Nayab Rasool, P. Hari Babu, D. B. Janaki Ramudu, M. V. Jyothi Kumar, Ch. Appa Rao, C. Naga Raju
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
(2018)
Article
Integrative & Complementary Medicine
Shaik Abdul Nabi, Ramesh Babu Kasetti, Swapna Sirasanagandla, Thandaiah Krishna Tilak, Malaka Venkateshwarulu Jyothi Kumar, Chippada Appa Rao
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2013)
Article
Chemistry, Medicinal
Guda Mallikarjuna Reddy, Akkarapalli Muralikrishna, Venkatapuram Padmavathi, Adivireddy Padmaja, Thandaiah Krishna Tilak, Chippada Appa Rao
CHEMICAL & PHARMACEUTICAL BULLETIN
(2013)
Article
Food Science & Technology
Ramesh Babu Kasetti, Shaik Abdul Nabi, Sirasangandla Swapna, Chippada Apparao
FOOD AND CHEMICAL TOXICOLOGY
(2012)
Article
Urology & Nephrology
Yanala Sandeep Reddy, Shaik Abbdul Nabi, Chippada Apparao, Chinthamaneni Srilatha, Yadla Manjusha, Parvathina Sri Ram Naveen, Chennu Krishna Kishore, Anappindi Sridhar, Vishnubotla Siva Kumar
Article
Spectroscopy
Y. Harinath, D. Harikishore Kumar Reddy, B. Naresh Kumar, Ch Apparao, K. Seshaiah
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2013)