Journal
FOLIA MICROBIOLOGICA
Volume 60, Issue 5, Pages 373-374Publisher
SPRINGER
DOI: 10.1007/s12223-014-0368-5
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Funding
- Czech Science Foundation [GA14-23022S]
- Ministry of Education of the Czech Republic [LO1302]
- RVO project [61388963]
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Candida parapsilosis produces secreted aspartic proteinases (Saps), which contribute to the virulence of this opportunistic pathogen. Gene family containing as many as 14 sequences potentially encoding secreted aspartic proteinases was identified in C. parapsilosis genome. Of them, SAPP1 and SAPP2 genes have been extensively characterized, but only now do we report that two SAPP2 homologs sharing 91.5% identity occur in C. parapsilosis genome. Existence of SAPP2 homologs points to unexpected complexity of the SAPP gene family.
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