Journal
FITOTERAPIA
Volume 80, Issue 1, Pages 68-72Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2008.10.001
Keywords
Ferula glauca L.; Apiaceae; Essential oil; Antimicrobial activity
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The essential oil obtained from different parts of Ferula glauca L (formerly considered as a subspecies of F. communis) growing in Marche (central Italy), was analyzed for the first time by GC-FID and GC-MS. The major volatiles were (E)-caryophyllene and caryophyllene oxide in leaves, alpha-pinene, myrcene and germacrene D in flowers, alpha- and beta-pinene in fruits, (E)-beta-farnesene, myristicin and elemicin in roots, respectively. The differences in composition detected with respect to E communis, made the volatile fraction a reliable marker to distinguish between them, and confirm the botanical data at the base of their discrimination. Furthermore, the oil was assayed for its antimicrobial activity by the broth microdilution method. B. subtilis was found to be the most sensitive microorganism, with the lowest MIC values. (C) 2008 Elsevier B.V. All rights reserved.
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