Article
Environmental Sciences
Basant Pradhan, Rohan Jayaratne, Helen Thompson, Giorgio Buonanno, Mandana Mazaheri, Mawutorli Nyarku, Weiwei Lin, Marcelo Luiz Pereira, Josef Cyrys, Annette Peters, Lidia Morawska
Summary: Epidemiological studies often use a single monitoring site in urban areas to investigate the association between particle exposure and health effects. However, for ultrafine particles (PNC), the central site cannot consistently represent personal exposure, as they are affected by different sources.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Suzanne Beauchemin, Christine Levesque, Clare L. S. Wiseman, Pat E. Rasmussen
Summary: This study investigated metal concentrations in ultrafine particle fraction (UFP) isolated from road dust in Toronto, Canada. Results showed marked enrichment of Cd, Cr, Zn, and V concentrations in UFP compared to the dust box material. UFP from arterial roads contained higher concentrations of Cd, Zn, and V compared to UFP from local roads, and the elevated concentrations of transition metals in UFP could potentially cause oxidative stress in lung cells, posing a human health concern.
Article
Environmental Sciences
Jules Kerckhoffs, Gerard Hoek, Ulrike Gehring, Roel Vermeulen
Summary: This study developed robust nation-wide models for long-term UFP exposure through combining mobile monitoring with long-term regional background monitoring. Minor differences in predictive performance between different algorithms were found, but the deconvolution approach is considered more physically realistic. The models will be applied in Dutch nation-wide health studies.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Provat K. Saha, Albert A. Presto, Steve Hankey, Julian D. Marshall, Allen L. Robinson
Summary: Studies have shown that racial-ethnic minorities in the United States are exposed to higher levels of ultrafine particles (UFP) than the national average, especially in densely populated metropolitan areas. These disparities are mainly driven by structural factors and cannot be solely explained by differences in income.
ENVIRONMENTAL RESEARCH LETTERS
(2022)
Article
Engineering, Environmental
Annie Doubleday, Magali N. N. Blanco, Elena Austin, Julian D. D. Marshall, Timothy V. V. Larson, Lianne Sheppard
Summary: Mobile monitoring is increasingly used to assess exposure to traffic-related air pollutants, but it may not represent residential exposures commonly used for epidemiologic studies. This study developed an approach to adjust mobile measurements and compared them to stationary measurements. The results showed that after adjustment, mobile measurements were more representative of cohort locations and provided more spatial variation. It is recommended to correct mobile measurements for accurate exposure predictions.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
M. Lopez, C. Reche, E. Perez-Albaladejo, C. Porte, A. Balasch, E. Monfort, E. Eljarrat, M. Viana
Summary: Electronic waste is one of the fastest growing waste streams in the world, and the fine and ultrafine particles generated during its processing may have potential impacts on human health and the environment.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Femke Bouma, Nicole A. H. Janssen, Joost Wesseling, Sjoerd van Ratingen, Maciek Strak, Jules Kerckhoffs, Ulrike Gehring, Wouter Hendricx, Kees de Hoogh, Roel Vermeulen, Gerard Hoek
Summary: This study investigated the associations between long-term exposure to ultrafine particles and natural and cause-specific mortality in the Netherlands. The results showed that long-term exposure to ultrafine particles was associated with increased respiratory disease and lung cancer mortality, but a weaker association with cardiovascular disease mortality.
ENVIRONMENT INTERNATIONAL
(2023)
Review
Environmental Sciences
Sultan F. I. Abdillah, Ya-Fen Wang
Summary: This review provides insights into the problem of ultrafine particles (UFPs), including their sources, physicochemical properties, measurement methods, and health impacts. Expensive instruments and the lack of standardized measurement methods hinder the current development of UFPs studies. The review also presents the development of low-cost UFPs sensors for future research references.
ENVIRONMENTAL RESEARCH
(2023)
Article
Toxicology
Nicholas L. Drury, Toriq Mustapha, Ross A. Shore, Jiayun Zhao, Gus A. Wright, Aline Rodrigues Hoffmann, Susanne U. Talcott, Annette Regan, Robert M. Tighe, Renyi Zhang, Natalie M. Johnson
Summary: Research suggests that pregnant women exposed to ultrafine particles during pregnancy may experience abnormal immune responses to influenza, increasing the severity of infection.
PARTICLE AND FIBRE TOXICOLOGY
(2023)
Article
Environmental Sciences
Guilherme Malafaia, Thiarlem Marinho da Luz, Amanda Pereira da Costa Araujo, Mohamed Ahmed Ibrahim Ahmed, Teresa Rocha-Santos, Damia Barcelo
Summary: This study aimed to assess and validate a protocol for optimizing the identification and quantification of polyethylene microplastics (PE MPs) in biological samples. The use of acetonitrile for digestion of cellulosic membranes was found to prevent loss of particles and promote good dispersion of MPs. Neubauer chambers showed good recovery rates and consistent results for quantifying MPs in samples with different concentrations.
ENVIRONMENTAL POLLUTION
(2022)
Article
Critical Care Medicine
Rosalind J. Wright, Hsiao-Hsien Leon Hsu, Yueh-Hsiu Mathilda Chiu, Brent A. Coull, Matthew C. Simon, Neelakshi Hudda, Joel Schwartz, Itai Kloog, John L. Durant
Summary: This study investigated the impact of prenatal exposure to ambient ultrafine particles (UFPs) on childhood asthma development, finding that prenatal UFP exposure was associated with asthma development in children, affecting males and females similarly, but females exposed to higher UFP concentrations during late pregnancy had the highest risk.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Environmental Sciences
Seny Damayanti, Roy M. Harrison, Francis Pope, David C. S. Beddows
Summary: Diesel engines contribute significantly to the emissions of Black Carbon (BC) and ultrafine particles. Analysis of data from a continuous monitoring site in London reveals that despite the use of Diesel Oxidation Catalyst (DOC) and Diesel Particle Filter (DPF), concentrations of ultrafine particles still exceed the WHO threshold for high concentrations. While BC emissions have decreased significantly, ultrafine particle counts have only declined by a small margin. This highlights the need for more effective abatement technologies in locations with heavy diesel traffic.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Chemistry, Physical
Arezoo Damokhi, Saeed Yousefinejad, Reza Yarmohammadi, Saeed Jafari
Summary: Ionic liquids are widely used as excellent solvents for the extraction and separation of organic and inorganic analytes due to their unique characteristics. They have shown good performance in biological monitoring for pre-concentrating and separating common pollutants in occupational exposure.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Environmental Sciences
Hongjin Li, Dong Xu, Huichu Li, Yihan Wu, Yu Cheng, Zhe Chen, Guanjin Yin, Weidong Wang, Yihui Ge, Yue Niu, Cong Liu, Jing Cai, Haidong Kan, Dedong Yu, Renjie Chen
Summary: The study found that children exposed to ultrafine particles (UFPs) may suffer from inflammation, decreased lung function, and reduced buccal microbe diversity. Specifically, UFP exposure was associated with increased levels of FeNO and TNF-alpha, reduced lung function, and decreased diversity of buccal microflora.
ENVIRONMENTAL POLLUTION
(2021)
Review
Public, Environmental & Occupational Health
Otto Creutzenberg, Gerhard Pohlmann, Dirk Schaudien, Heiko Kock
Summary: The study found that nanomaterials tend to aggregate into microscale clusters rather than existing as individual nanoparticles, showing little potential to translocate beyond the lungs into the bloodstream.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Respiratory System
Arnaud Scherpereel, Isabelle Opitz, Thierry Berghmans, Ioannis Psallidas, Markus Glatzer, David Rigau, Philippe Astoul, Servet Bolukbas, Jeanette Boyd, Johan Coolen, Charlotte De Bondt, Dirk De Ruysscher, Valerie Durieux, Corinne Faivre-Finn, Dean Fennell, Francoise Galateau-Salle, Laurent Greillier, Mir Ali Hoda, Walter Klepetko, Aude Lacourt, Phil McElnay, Nick A. Maskell, Luciano Mutti, Jean-Claude Pairon, Paul Van Schil, Jan P. van Meerbeeck, David Waller, Walter Weder, Giuseppe Cardillo, Paul Martin Putora
EUROPEAN RESPIRATORY JOURNAL
(2020)
Article
Environmental Sciences
Guyguy Manangama, Sabyne Audignon-Durand, Lucile Migault, Celine Gramond, Cecile Zaros, Raphaelle Teysseire, Loic Sentilhes, Patrick Brochard, Aude lacourt, Fleur Delva
ENVIRONMENTAL RESEARCH
(2020)
Article
Environmental Sciences
Guyguy Manangama, Celine Gramond, Sabyne Audignon-Durand, Isabelle Baldi, Pascale Fabro-Peray, Annabelle Gilg Soit Ilg, Pascal Guenel, Pierre Lebailly, Daniele Luce, Isabelle Stucker, Patrick Brochard, Aude Lacourt
ENVIRONMENTAL RESEARCH
(2020)
Article
Multidisciplinary Sciences
Emilie Leveque, Aude Lacourt, Viviane Philipps, Daniele Luce, Pascal Guenel, Isabelle Stucker, Cecile Proust-Lima, Karen Leffondre
Article
Public, Environmental & Occupational Health
Evguenia Krastinova, Valerie Garrait, Marie-Therese Lecam, Andre Coste, Emmanuelle Varon, Isabelle Delacroix, Amine Si Ali, Camille Jung, Mounira Smati, Muriel Cherbit, Bernard Maitre, Jean-Claude Pairon, Pascal Andujar
Summary: This study investigated infection rates among healthcare workers during the peak of the SARS-CoV-2 epidemic in France and found that direct patient contact and presence of anosmia were independently associated with positive RT-PCR results. Household transmission from healthcare workers was reported in 14% of cases, with 2 deaths occurring. Only 31% of healthcare workers were able to wear masks at home, highlighting potential risks for household transmission.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Sabyne Audignon-Durand, Celine Gramond, Stephane Ducamp, Guyguy Manangama, Alain Garrigou, Fleur Delva, Patrick Brochard, Aude Lacourt
Summary: This study aimed to develop a job-exposure matrix dedicated to UFPs by assessing the association between fifty-seven work processes and the emitted UFPs. Results showed that 52.8% of the assessed occupational codes were associated with UFP exposure, with 42.6% involving very probable exposure and at a high frequency.
ANNALS OF WORK EXPOSURES AND HEALTH
(2021)
Letter
Critical Care Medicine
Frederique Schortgen, Pascal Andujar, Amine Si Ali, Layla Yahyaoui, Mounira Smati-Lafarge
INTENSIVE CARE MEDICINE
(2021)
Article
Environmental Sciences
Mireille Matrat, Murielle Gain, Corinne Haioun, Fabien Le Bras, Catherine Nisse, Franck Morschhauser, Benedicte Clin, Isabelle Baldi, Catherine Verdun-Esquer, Robert Garnier, Herve Laborde-Casterot, Fabrice Herin, Yolande Esquirol, Pascal Andujar, Milia Belacel, Christos Chouaid, Claire Chauvet, Gerard Lasfargues, Jean-Claude Pairon
Summary: The questionnaire developed in this study showed high sensitivity and specificity in identifying patients with non-Hodgkin lymphoma who may have been affected by environmental or occupational exposure. 15% of the subjects were invited to apply for compensation for occupational disease, mainly due to exposure to pesticides and solvents.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Francois Laurent, Ilyes Benlala, Gael Dournes, Celine Gramond, Isabelle Thaon, Benedicte Clin, Patrick Brochard, Antoine Gislard, Pascal Andujar, Soizick Chammings, Justine Gallet, Aude Lacourt, Fleur Delva, Christophe Paris, Gilbert Ferretti, Jean-Claude Pairon
Summary: The study found no association between interstitial lung abnormalities and asbestos exposure index, but a positive relationship with age. Emphysema was associated with age, and definite or possible UIP pattern showed a significant positive association with age.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Environmental Sciences
Ilyes Benlala, Baudouin Denis De Senneville, Gael Dournes, Morgane Menant, Celine Gramond, Isabelle Thaon, Benedicte Clin, Patrick Brochard, Antoine Gislard, Pascal Andujar, Soizick Chammings, Justine Gallet, Aude Lacourt, Fleur Delva, Christophe Paris, Gilbert Ferretti, Jean-Claude Pairon, Francois Laurent
Summary: This study developed and validated an automated AI-driven quantification method for pleural plaques in a population of retired workers previously exposed to asbestos. The results showed that AI accurately measured the volume and extent of pleural plaques and demonstrated the progression of these plaques over a five-year period. This method provides a valuable tool for further investigating the relationship between pleural plaques, respiratory function, and thoracic malignancy.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Justine Gallet, Francois Laurent, Christophe Paris, Benedicte Clin, Antoine Gislard, Isabelle Thaon, Soizick Chammings, Celine Gramond, Guy Ogier, Gilbert Ferretti, Pascal Andujar, Patrick Brochard, Fleur Delva, Jean-Claude Pairon, Aude Lacourt
Summary: This study aimed to evaluate the association between occupational asbestos exposure and lung cancer with pleural plaques (PP). The results showed a significant association between PP and lung cancer incidence and mortality, particularly in non-smokers.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Review
Chemistry, Multidisciplinary
Vanessa Marques Da Silva, Manon Benjdir, Pierrick Montagne, Jean-Claude Pairon, Sophie Lanone, Pascal Andujar
Summary: The toxicity of silicon dioxide depends on its crystalline form and the size of nanoscale particles. Manufactured amorphous silica nanoparticles may have similar toxicity to crystalline silica. This article provides a comprehensive review of the pulmonary effects of silica on non-tumor tissues, including in vitro and in vivo experimental studies.
Article
Oncology
Sebastien Gendarme, Jean-Claude Pairon, Pascal Andujar, Francois Laurent, Patrick Brochard, Fleur Delva, Benedicte Clin, Antoine Gislard, Christophe Paris, Isabelle Thaon, Helene Goussault, Florence Canoui-Poitrine, Christos Chouaid
Summary: This study analyzed the cost-effectiveness ratio of implementing a lung cancer screening program for asbestos-exposed population. The results show that biennial screening for smokers with high asbestos exposure is cost-effective.
Article
Public, Environmental & Occupational Health
Antoine Villa, Arna Geshkovska, Gauthier Bellagamba, Isabelle Baldi, Mathieu Molimard, Catherine Verdun-Esquer, Marie-Pascale Lehucher-Michel, Mireille Canal-Raffin
Summary: This study investigates the internal contamination of healthcare professionals by antineoplastic drugs and the factors associated with it. The use of gloves and the contaminating nature of tasks involving antineoplastic drugs were found to be protective factors against contamination. Additionally, providing sufficient information and proper waste disposal were identified as contributing factors to internal contamination.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Meeting Abstract
Public, Environmental & Occupational Health
Alexis Descatha, Marc Fadel, Sabrina Pitet, Catherine Verdun-Esquer, Yolande Esquirol, Clement Legeay, Aurelien Dinh, Brigitte Clodore, Pascal Duprat, Sandrine Cartegnie, Celine Dagrenat, Jean-Pierre Leclerc, Pascal Andujar, Corinne Letheux, Audrey Petit, Yves Roquelaure
SAFETY AND HEALTH AT WORK
(2022)