Article
Critical Care Medicine
Samuel J. Gentle, Colm P. Travers, Matthew Clark, Waldemar A. Carlo, Namasivayam Ambalavanan
Summary: In extremely preterm infants on respiratory support on postnatal day 28, the presence and longer duration of patent ductus arteriosus (PDA) were associated with the development of bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH).
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Agriculture, Dairy & Animal Science
J. Daniel Barreiro-Vazquez, Marta Miranda, Andres Barreiro-Lois
Summary: This study aimed to establish a protocol for renal Doppler ultrasound in adult healthy Holstein-Friesian cows and provide reference values for renal resistive index (RI) and pulsatility index (PI). The right kidney in cattle is always visible through a right abdominal window, while the left kidney is rarely accessible. Normal RI and PI values for the right kidney were 0.49 +/- 0.07 and 0.70 +/- 0.15, and for the left kidney were 0.53 +/- 0.05 and 0.79 +/- 0.11 in healthy Holstein-Friesian cows. An upper cut-off value for RI of 0.63 and for PI of 1.00 is suggested.
Article
Acoustics
D. P. Ngwezi, M. McClean, A. McBrien, L. Eckersley, J. Abeysekera, T. Colen, L. K. Hornberger
Summary: The inability to visualize branch pulmonary arteries in the same plane, often associated with abnormal ductus arteriosus insertion, and/or a posterior pulmonary artery bifurcation angle of >= 105 degrees are predictive features of postnatal ductus arteriosus-related branch pulmonary stenosis in fetuses with pulmonary atresia.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Article
Pediatrics
Hythem Nawaytou, Nancy K. K. Hills, Ronald I. I. Clyman
Summary: The study aimed to investigate the impact of prolonged exposure to moderate/large patent ductus arteriosus left-to-right shunt (PDA) on the risk of late pulmonary hypertension (BPD-PH) and pulmonary vascular disease (BPD-PVD) in preterm infants with bronchopulmonary dysplasia (BPD). The results showed that moderate/large PDA shunts that persisted beyond 36 weeks were significantly associated with an increased incidence of flow-associated BPD-PH. However, there was no evidence to suggest an association between the duration of PDA exposure and the incidence of BPD-PVD during neonatal hospitalization in preterm infants with BPD.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Bartolomeo Bo, Flaminia Pugnaloni, Amelia Licari, Neil Patel, Brigitte Strizek, Lotte Lemloh, Judith Leyens, Andreas Mueller, Florian Kipfmueller
Summary: The pattern of flow through the ductus arteriosus (DA) is associated with the need for ECMO or death in neonates with CDH. A VTI ratio <1.0 is a valuable threshold to identify high-risk CDH neonates. Other parameters should be considered for improved risk stratification.
PEDIATRIC PULMONOLOGY
(2023)
Article
Medicine, General & Internal
Zeming Zhou, Yuanrui Gu, Hong Zheng, Chaowu Yan, Qiong Liu, Shiguo Li, Huijun Song, Zhongying Xu, Jinglin Jin, Haibo Hu, Jianhua Lv
Summary: This retrospective study enrolled 134 consecutive patients with large patent ductus arteriosus (PDA) and severe pulmonary hypertension (PH) to explore the factors affecting PH prognosis. The results showed that postoperative mPAP was an independent risk factor for follow-up PH. Patients with a postoperative mPAP >35.5 mmHg should consider targeted medical therapy or undergo right heart catheterization again.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Grant S. Roberts, Anthony Peret, Erin M. Jonaitis, Rebecca L. Koscik, Carson A. Hoffman, Leonardo A. Rivera-Rivera, Karly A. Cody, Howard A. Rowley, Sterling C. Johnson, Oliver Wieben, Kevin M. Johnson, Laura B. Eisenmenger
Summary: This study used four-dimensional flow MRI to comprehensively evaluate cerebral hemodynamics in middle-aged and older adults, and found that age and sex have an impact on blood flow and pulsatility.
Article
Obstetrics & Gynecology
Jiang-Nan Wu, Ming-Qing Li, Feng Xie, Bin Zhang
Summary: The study found that the second-trimester measured UtA indices had a satisfactory performance at the 9th week in predicting subsequent preeclampsia. The right UtA-RI was the first choice in ruling out preeclampsia, while the left UtA-PI showed the best authenticity of the prediction.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Pediatrics
Christopher C. Buckland, James E. Potts, John B. Mawson, J. A. Gordon Culham
Summary: This article illustrates the association between the ductus arteriosus and various congenital cardiac, vascular, and pulmonary lesions, which can impact different circulatory systems and airways.
PEDIATRIC RADIOLOGY
(2022)
Article
Medicine, General & Internal
Stephen Contag, Silvia Visentin, Katherine Goetzinger, Erich Cosmi
Summary: The study compared the effectiveness of cerebral-placental ratio (CPR) and cerebral-renal ratio (CRR) in predicting adverse neonatal outcomes among growth-restricted fetuses. The results showed that the umbilical artery pulsatility index performed the best in detecting composite adverse neonatal outcomes, with no additional benefit from using CRR compared to CPR. The data did not support the use of renal artery Doppler as a useful clinical test for identifying fetuses at risk for adverse neonatal outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Pediatrics
Asmaa A. Osman, Muflih Albalawi, Shyamala Dakshinamurti, Martha Hinton, Fatema Elhawary, Wegdan Mawlana, Yasser Elsayed
Summary: This study aimed to investigate changes in perfusion index and other vital signs before, during, and after PDA treatment in preterm infants, as well as the utility of PI and other vital sign histograms in early prediction of hsPDA. The study found that episodes of low PI and high PI were significantly longer in infants with PDA before treatment compared to those in infants with PDA during and after treatment. Low PI correlated with echocardiography indices of hsPDA, suggesting that PI variability may serve as an early marker for hsPDA.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Letter
Medicine, General & Internal
John van den Anker
Summary: This article discusses the management of patent ductus arteriosus (PDA) and finds that expectant management is noninferior to early ibuprofen treatment in preventing complications and death. However, the study did not consider the fact that a significant percentage of infants in both groups also received acetaminophen, which has been found to have similar effectiveness to ibuprofen for PDA closure.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Tim Hundscheid, Wes Onland, Elisabeth M. W. Kooi, Daniel C. Vijlbrief, Willem B. de Vries, Koen P. Dijkman, Anton H. van Kaam, Eduardo Villamor, Andre A. Kroon, Remco Visser, Susanne M. Mulder-de Tollenaer, Barbara De Bisschop, Peter H. Dijk, Daniela Avino, Catheline Hocq, Alexandra Zecic, Marisse Meeus, Tessa de Baat, Frank Derriks, Tine B. Henriksen, Kasper J. Kyng, Rogier Donders, Debbie H. G. M. Nuytemans, Bart Van Overmeire, Antonius L. Mulder, Willem P. de Boode
Summary: This trial showed that in the treatment of PDA in extremely preterm infants, expectant management was noninferior to early ibuprofen treatment in terms of necrotizing enterocolitis, bronchopulmonary dysplasia, or death at 36 weeks' postmenstrual age.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Vivek Bagaria, N. S. Sujith, C. S. Hiremath, Shekhar Rao
Summary: Extrinsic compression of the pulmonary veins can be caused by cardiomegaly or aneurysm, leading to narrowing and turbulence. Recent advancements allow for management of this condition without direct intervention on the pulmonary veins, reducing the risk of recurrence.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Developmental Biology
Silvia Amodeo, Paolo Ivo Cavoretto, Anna Seidenari, Giuseppe Paci, Chiara Germano, Francesca Monari, Valeria Donno, Laura Giambanco, Laura Avagliano, Daniela Di Martino, Federica Fuse, Bianca Masturzo, Vito Chiantera, Fabio Facchinetti, Enrico Ferrazzi, Massimo Candiani, Gaetano Bulfamante, Antonio Farina
Summary: This study investigated the relationship between maternal vascular malperfusions (MVM) and second trimester uterine arteries pulsatility index (UtA-PI) in cases of stillbirth. The results showed significant correlations between several MVM findings and UtA-PI, suggesting the importance of third trimester follow-up for cases with increased UtA-PI to improve reproductive chances for these pregnant patients.