Journal
FETAL AND PEDIATRIC PATHOLOGY
Volume 32, Issue 3, Pages 213-217Publisher
INFORMA HEALTHCARE
DOI: 10.3109/15513815.2012.721475
Keywords
factor V Leiden; inherited thrombophilia; preeclampsia
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Objective: The aim was to determine whether inherited thrombophilia increases the risk of preeclampsia (PE) or interferes with its clinical course. Material and Methods: We included 50 patients with severe PE and 50 healthy pregnant women. Patients were evaluated for inherited thrombophilia. Results: Fourteen patients in the study group was factor V Leiden (FVL) carrier while it was 12% in the control group. In women with PE, FVL and other inherited thrombophilic factors were not more prevalent than in the controls. Conclusion: The present study failed to demonstrate an association between the inherited thrombophilias and PE.
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