Journal
FERTILITY AND STERILITY
Volume 95, Issue 1, Pages 389-392Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2010.07.1045
Keywords
Primary ciliary dyskinesia; PCD; ICSI; pregnancy
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Spermatozoa viability tests based on dual-color flow cytometry after staining with Sybr-14/propidium iodide were performed on 44 men with complete asthenospermia for primary ciliary dyskinesia (PCD) screening, and seven were identified with PCD by electron microscopy of ultrastructural ciliary defects. Six PCD patients underwent eight intracytoplasmic sperm injection therapy cycles using ejaculated sperm or testicular sperm, obtaining a mean fertilization rate of 46.6%, with three healthy babies born and one in utero at the time of writing. (Fertil Steril (R) 2011;95:389-92. (C) 2011 by American Society for Reproductive Medicine.)
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