Phenotypes selected during chronic lung infection in cystic fibrosis patients: implications for the treatment ofPseudomonas aeruginosabiofilm infections

In VivoPharmacokinetics/Pharmacodynamics of Colistin and Imipenem in Pseudomonas aeruginosa Biofilm Infection

(2012) Wang Hengzhuang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The metabolically active subpopulation inPseudomonas aeruginosabiofilms survives exposure to membrane-targeting antimicrobials via distinct molecular mechanisms

(2012) Wen-Chi Chiang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

The roles of biofilm matrix polysaccharide Psl in mucoidPseudomonas aeruginosabiofilms

(2012) Luyan Ma et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Heterogeneity in Pseudomonas aeruginosa Biofilms Includes Expression of Ribosome Hibernation Factors in the Antibiotic-Tolerant Subpopulation and Hypoxia-Induced Stress Response in the Metabolically Active Population

(2012) K. S. Williamson et al.   JOURNAL OF BACTERIOLOGY

Early antibiotic treatment forPseudomonas aeruginosaeradication in patients with cystic fibrosis: a randomised multicentre study comparing two different protocols

(2012) Giovanni Taccetti et al.   THORAX

Levofloxacin Inhalation Solution (MP-376) in Patients with Cystic Fibrosis withPseudomonas aeruginosa

(2011) David E. Geller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pseudomonas aeruginosaPopulation Diversity and Turnover in Cystic Fibrosis Chronic Infections

(2011) Eilidh Mowat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dynamics of Mutator and Antibiotic-Resistant Populations in a Pharmacokinetic/Pharmacodynamic Model of Pseudomonas aeruginosa Biofilm Treatment

(2011) María D. Macià et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antagonistic Interactions of Pseudomonas aeruginosa Antibiotic Resistance Mechanisms in Planktonic but Not Biofilm Growth

(2011) Xavier Mulet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem on Mucoid and Nonmucoid Pseudomonas aeruginosa Biofilms

(2011) Wang Hengzhuang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mucoid Pseudomonas aeruginosa isolates maintain the biofilm formation capacity and the gene expression profiles during the chronic lung infection of CF patients

(2011) BAOLERI LEE et al.   APMIS

Recent advances in the treatment of Pseudomonas aeruginosainfections in cystic fibrosis

(2011) Niels Høiby   BMC Medicine

Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM)

(2011) Lotte Frigaard Mandsberg et al.   FEMS MICROBIOLOGY LETTERS

Aztreonam for inhalation solution (AZLI) in patients with cystic fibrosis, mild lung impairment, and P. aeruginosa

(2011) C.E. Wainwright et al.   Journal of Cystic Fibrosis

Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis

(2011) Nicole Mayer-Hamblett et al.   PEDIATRIC PULMONOLOGY

Evolutionary dynamics of bacteria in a human host environment

(2011) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early adaptive developments ofPseudomonas aeruginosaafter the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

(2010) Martin Holm Rau et al.   ENVIRONMENTAL MICROBIOLOGY

Pseudomonas aeruginosabiofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies

(2010) Daniel J Hassett et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Colistin‐Tobramycin Combinations Are Superior to Monotherapy Concerning the Killing of BiofilmPseudomonas aeruginosa

(2010) Gloria Herrmann et al.   JOURNAL OF INFECTIOUS DISEASES

Antibiotic Resistance in Pseudomonas aeruginosa Strains with Increased Mutation Frequency Due to Inactivation of the DNA Oxidative Repair System

(2009) L. F. Mandsberg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: A review

(2009) Felix Ratjen et al.   Journal of Cystic Fibrosis

Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus

(2009) Harry Heijerman et al.   Journal of Cystic Fibrosis

Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants

(2009) O. Ciofu et al.   MICROBIOLOGY-SGM

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Inhalable Antibiotic Delivery Using a Dry Powder Co-delivering Recombinant Deoxyribonuclease and Ciprofloxacin for Treatment of Cystic Fibrosis

(2009) Yan Yang et al.   PHARMACEUTICAL RESEARCH

Role of Mutation in Pseudomonas aeruginosa Biofilm Development

(2009) Tim C. R. Conibear et al.   PLoS One

Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

(2009) M Kolpen et al.   THORAX

Inactivation of Efflux Pumps Abolishes Bacterial Biofilm Formation

(2008) M. Kvist et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Chromosomal mechanisms of aminoglycoside resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients

(2008) S. Islam et al.   CLINICAL MICROBIOLOGY AND INFECTION

Increased mutability of Pseudomonas aeruginosa in biofilms

(2008) K. Driffield et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients

(2008) Helle Krogh Johansen et al.   Journal of Cystic Fibrosis

Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience

(2008) C.R. Hansen et al.   Journal of Cystic Fibrosis

Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes

(2008) Sünje Johanna Pamp et al.   MOLECULAR MICROBIOLOGY

Endogenous oxidative stress produces diversity and adaptability in biofilm communities

(2008) B. R. Boles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA