The trans isomer of Tau peptide is prone to aggregate, and the WW domain of Pin1 drastically decreases its aggregation

Molecular Mechanism of Pin1–Tau Recognition and Catalysis

(2016) Timo Eichner et al.   JOURNAL OF MOLECULAR BIOLOGY

Potential of the Antibody Against cis–Phosphorylated Tau in the Early Diagnosis, Treatment, and Prevention of Alzheimer Disease and Brain Injury

(2016) Kun Ping Lu et al.   JAMA Neurology

Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

(2015) Asami Kondo et al.   NATURE

Structural Impact of Tau Phosphorylation at Threonine 231

(2015) Martin Schwalbe et al.   STRUCTURE

The C113D Mutation in Human Pin1 Causes Allosteric Structural Changes in the Phosphate Binding Pocket of the PPIase Domain through the Tug of War in the Dual-Histidine Motif

(2014) Ning Xu et al.   BIOCHEMISTRY

Interdomain Interactions Support Interdomain Communication in Human Pin1

(2013) Kimberly A. Wilson et al.   BIOCHEMISTRY

Kinetic Isotope Effects Support the Twisted Amide Mechanism of Pin1 Peptidyl-Prolyl Isomerase

(2013) Ana Y. Mercedes-Camacho et al.   BIOCHEMISTRY

Peptidyl-prolyl isomerase activity of FK506 binding protein 12 prevents tau peptide from aggregating

(2013) T. Ikura et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Non-catalytic participation of the Pin1 peptidyl-prolyl isomerase domain in target binding

(2013) Brendan T. Innes et al.   Frontiers in Physiology

Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease

(2012) Kazuhiro Nakamura et al.   CELL

Mapping the Potential Energy Landscape of Intrinsically Disordered Proteins at Amino Acid Resolution

(2012) Valéry Ozenne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Sheet Core of Tau Paired Helical Filaments Revealed by Solid-State NMR

(2012) Venita Daebel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A 68 residue N-terminal fragment of pro-atrial natriuretic peptide is a monomeric intrinsically unstructured protein

(2011) Dan L. Crimmins et al.   JOURNAL OF BIOCHEMISTRY

Three-/four-repeat-dependent aggregation profile of tau microtubule-binding domain clarified by dynamic light scattering analysis

(2009) Etsuko Sugino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS