Tumor suppressor microRNAs: A novel non-coding alliance against cancer

MicroRNA-375 targets PDK1 in pancreatic carcinoma and suppresses cell growth through the Akt signaling pathway

(2014) JIAN ZHOU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

MiR-15a-16 represses Cripto and inhibits NSCLC cell progression

(2014) Feng Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells

(2014) LIFENG MIAO et al.   Oncology Letters

DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells

(2013) Akio Iio et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Caprin-1 is a novel microRNA-223 target for regulating the proliferation and invasion of human breast cancer cells

(2013) Bo Gong et al.   BIOMEDICINE & PHARMACOTHERAPY

MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells

(2013) Lihua Zhang et al.   BMC CANCER

MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3

(2013) Bingtian Zhao et al.   CANCER LETTERS

The locus of microRNA-10b

(2013) Francesca Biagioni et al.   CELL CYCLE

Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors

(2013) L Vian et al.   CELL DEATH AND DIFFERENTIATION

MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells

(2013) Tao Yang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The proto-oncogene ERG is a target of microRNAmiR-145in prostate cancer

(2013) Martin Hart et al.   FEBS Journal

Let-7c inhibits A549 cell proliferation through oncogenic TRIB2 related factors

(2013) Ping-Yu Wang et al.   FEBS LETTERS

Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR-145

(2013) DONG REN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The TAL1 complex targets theFBXW7tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

(2013) Marc R. Mansour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNAs Transfer from Human Macrophages to Hepato-Carcinoma Cells and Inhibit Proliferation

(2013) A. Aucher et al.   JOURNAL OF IMMUNOLOGY

Lipoxins Attenuate Renal Fibrosis by Inducing let-7c and Suppressing TGF R1

(2013) E. P. Brennan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A TrkB–STAT3–miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells

(2013) Wei Bao et al.   Molecular Cancer

miR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death

(2013) Zhiyu Chen et al.   Molecular Cancer

Let-7c Governs the Acquisition of Chemo- or Radioresistance and Epithelial-to-Mesenchymal Transition Phenotypes in Docetaxel-Resistant Lung Adenocarcinoma

(2013) Shi-Yun Cui et al.   MOLECULAR CANCER RESEARCH

Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells

(2013) S Masciarelli et al.   ONCOGENE

microRNA-223 promotes the growth and invasion of glioblastoma cells by targeting tumor suppressor PAX6

(2013) BAI-SHENG HUANG et al.   ONCOLOGY REPORTS

Expression of miR-142-5p in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Chronic Antibody-Mediated Rejection

(2013) Richard Danger et al.   PLoS One

miR-223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin-like growth factor-1 receptor and cyclin-dependent kinase 2

(2013) WEIQI NIAN et al.   Oncology Letters

Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204

(2013) Ohad Shaham et al.   PLoS Genetics

Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression

(2012) G. Zardo et al.   BLOOD

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer

(2012) N. Ismail et al.   BLOOD

VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma

(2012) Olga Mikhaylova et al.   CANCER CELL

MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells

(2012) P. N. Plummer et al.   CANCER RESEARCH

Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-like Phenotype

(2012) Z. Ying et al.   CANCER RESEARCH

MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF

(2012) Chao Zou et al.   CELL CYCLE

An anti-let-7 sponge decoys and decays endogenous let-7 functions

(2012) Xiangling Yang et al.   CELL CYCLE

Molecular Pathways: MicroRNAs as Cancer Therapeutics

(2012) S. A. Melo et al.   CLINICAL CANCER RESEARCH

miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours

(2012) Francesca Biagioni et al.   EMBO Molecular Medicine

MicroRNA-223 regulates FOXO1 expression and cell proliferation

(2012) Lihui Wu et al.   FEBS LETTERS

miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1

(2012) NOBUYOSHI TAKESHITA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells

(2012) Chen Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer

(2012) Claudia Piovan et al.   Molecular Oncology

Context-specific microRNA analysis: identification of functional microRNAs and their mRNA targets

(2012) Noa Bossel Ben-Moshe et al.   NUCLEIC ACIDS RESEARCH

Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells

(2012) Mohit Sachdeva et al.   NUCLEIC ACIDS RESEARCH

miRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia

(2012) A Pelosi et al.   ONCOGENE

MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha

(2012) H Zhang et al.   ONCOGENE

RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets

(2012) O A Kent et al.   ONCOGENE

Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression

(2012) A Pagliuca et al.   ONCOGENE

The molecular mechanism of microRNA-145 to suppress invasion–metastasis cascade in gastric cancer

(2012) P Gao et al.   ONCOGENE

Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop

(2012) J Zhang et al.   ONCOGENE

MicroRNA let-7c Is Downregulated in Prostate Cancer and Suppresses Prostate Cancer Growth

(2012) Nagalakshmi Nadiminty et al.   PLoS One

Identification of MicroRNAs Inhibiting TGF-β-Induced IL-11 Production in Bone Metastatic Breast Cancer Cells

(2012) Sirkku Pollari et al.   PLoS One

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

(2012) C. Polytarchou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How does Lin28 let-7 control development and disease?

(2012) James E. Thornton et al.   TRENDS IN CELL BIOLOGY

MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme

(2012) J Lin et al.   Cell Death & Disease

miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer

(2012) A Sacconi et al.   Cell Death & Disease

MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer

(2011) Seong O. Suh et al.   CARCINOGENESIS

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

Epigenetic regulation ofmicroRNA-10band targeting of oncogenicMAPRE1in gastric cancer

(2011) Kwoneel Kim et al.   Epigenetics

Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer

(2011) Hai-Bo Han et al.   JOURNAL OF PATHOLOGY

miRNA-223 Promotes Gastric Cancer Invasion and Metastasis by Targeting Tumor Suppressor EPB41L3

(2011) X. Li et al.   MOLECULAR CANCER RESEARCH

MicroRNA response to environmental mutagens in liver

(2011) Bahaeldin K. Elamin et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

(2011) Konstantinos J Mavrakis et al.   NATURE GENETICS

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis

(2011) Qing Xu et al.   NUCLEIC ACIDS RESEARCH

Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer

(2011) G Mudduluru et al.   ONCOGENE

DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

(2011) P Lopez-Serra et al.   ONCOGENE

MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R

(2011) Cheng You Jia et al.   PLoS One

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

(2011) A. Davalos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1

(2011) William CS Cho et al.   RNA Biology

A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy

(2010) W. Zhang et al.   ANNALS OF ONCOLOGY

Metastasis-related miRNAs, active players in breast cancer invasion, and metastasis

(2010) Ming Shi et al.   CANCER AND METASTASIS REVIEWS

A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells

(2010) Sonia A. Melo et al.   CANCER CELL

Concurrent Suppression of Integrin α5, Radixin, and RhoA Phenocopies the Effects of miR-31 on Metastasis

(2010) Scott Valastyan et al.   CANCER RESEARCH

MicroRNA145 Targets BNIP3 and Suppresses Prostate Cancer Progression

(2010) Xueqin Chen et al.   CANCER RESEARCH

EGFR Promotes Lung Tumorigenesis by Activating miR-7 through a Ras/ERK/Myc Pathway That Targets the Ets2 Transcriptional Repressor ERF

(2010) Y.-T. Chou et al.   CANCER RESEARCH

miR-31: A crucial overseer of tumor metastasis and other emerging roles

(2010) Scott Valastyan et al.   CELL CYCLE

Regulation of ErbB receptor signalling in cancer cells by microRNA

(2010) Andrew Barker et al.   CURRENT OPINION IN PHARMACOLOGY

Epigenetic Changes Induced by Air Toxics: Formaldehyde Exposure Alters miRNA Expression Profiles in Human Lung Cells

(2010) Julia E. Rager et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

microRNAs, RNA binding proteins and cancer

(2010) Reuven Agami   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-204/211 alters epithelial physiology

(2010) Fei E. Wang et al.   FASEB JOURNAL

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

(2010) O. A. Kent et al.   GENES & DEVELOPMENT

Evidence for microRNA involvement in exercise-associated neutrophil gene expression changes

(2010) Shlomit Radom-Aizik et al.   JOURNAL OF APPLIED PHYSIOLOGY

Identification of non-coding RNAs embracing microRNA-143/145 cluster

(2010) Akio Iio et al.   Molecular Cancer

Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

(2010) Li Ma et al.   NATURE BIOTECHNOLOGY

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miR-145-dependent targeting of Junctional Adhesion Molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness

(2010) M Götte et al.   ONCOGENE

MicroRNA-145 Targets YES and STAT1 in Colon Cancer Cells

(2010) Lea H. Gregersen et al.   PLoS One

miR-204 is required for lens and retinal development via Meis2 targeting

(2010) I. Conte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EGF Decreases the Abundance of MicroRNAs That Restrain Oncogenic Transcription Factors

(2010) R. Avraham et al.   Science Signaling

Network Modeling Identifies Molecular Functions Targeted by miR-204 to Suppress Head and Neck Tumor Metastasis

(2010) Younghee Lee et al.   PLoS Computational Biology

MiRNAs and Cancer

(2009) Rosa Visone et al.   AMERICAN JOURNAL OF PATHOLOGY

In vivo profile of the human leukocyte microRNA response to endotoxemia

(2009) Wolfgang M. Schmidt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

(2009) J. A. Pulikkan et al.   BLOOD

MicroRNA-145 Suppresses Cell Invasion and Metastasis by Directly Targeting Mucin 1

(2009) M. Sachdeva et al.   CANCER RESEARCH

A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers

(2009) B. C. Christensen et al.   CARCINOGENESIS

MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

(2009) Na Xu et al.   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-α in human breast cancer cells

(2009) R Spizzo et al.   CELL DEATH AND DIFFERENTIATION

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

(2009) Daniel T Starczynowski et al.   NATURE MEDICINE

HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling

(2009) James M. Hill et al.   NEUROREPORT

MicroRNA Fingerprints Identify miR-150 as a Plasma Prognostic Marker in Patients with Sepsis

(2009) Catalin Vasilescu et al.   PLoS One

Comprehensive Gene and microRNA Expression Profiling Reveals a Role for microRNAs in Human Liver Development

(2009) Galit Tzur et al.   PLoS One

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke

(2008) Alberto Izzotti et al.   FASEB JOURNAL

MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1

(2008) Queenie W.–L. Wong et al.   GASTROENTEROLOGY

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer

(2008) Hideki Yamada et al.   GENES CHROMOSOMES & CANCER

Antiproliferative Effects by Let-7 Repression of High-Mobility Group A2 in Uterine Leiomyoma

(2008) Y. Peng et al.   MOLECULAR CANCER RESEARCH

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

Translating insights from the cancer genome into clinical practice

(2008) Lynda Chin et al.   NATURE

MicroRNAs accurately identify cancer tissue origin

(2008) Nitzan Rosenfeld et al.   NATURE BIOTECHNOLOGY

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY