Kinetics of the early events of GPCR signalling

G Protein-Coupled Receptors: What a Difference a ‘Partner’ Makes

(2014) Benoît Roux et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endogenous CNS Expression of Neurotensin and Neurotensin Receptors Is Altered during the Postpartum Period in Outbred Mice

(2014) Terri M. Driessen et al.   PLoS One

Active Plasma Membrane P-type H+-ATPase Reconstituted into Nanodiscs Is a Monomer

(2013) Bo Højen Justesen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel, Gel-free Proteomics Approach Identifies RNF5 and JAMP as Modulators of GPCR Stability

(2013) Sébastien J. Roy et al.   MOLECULAR ENDOCRINOLOGY

Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets

(2012) Xiao-long Tang et al.   ACTA PHARMACOLOGICA SINICA

Modulation of the Interaction between Neurotensin Receptor NTS1 and Gq Protein by Lipid

(2012) Sayaka Inagaki et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of the agonist-bound neurotensin receptor

(2012) Jim F. White et al.   NATURE

Biophysical characterization of G-protein coupled receptor–peptide ligand bindingThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.

(2011) David N. Langelaan et al.   Biochemistry and Cell Biology

The role of the lipid matrix for structure and function of the GPCR rhodopsin

(2011) Olivier Soubias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Uncovering the intimate relationship between lipids, cholesterol and GPCR activation

(2011) Joanne Oates et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging

(2011) Rinshi S. Kasai et al.   JOURNAL OF CELL BIOLOGY

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Screening for GPCR Ligands Using Surface Plasmon Resonance

(2011) Iva Navratilova et al.   ACS Medicinal Chemistry Letters

Nanodiscs allow the use of integral membrane proteins as analytes in surface plasmon resonance studies

(2010) Julian M. Glück et al.   ANALYTICAL BIOCHEMISTRY

Use of the GTPγS ([35S]GTPγS and Eu-GTPγS) binding assay for analysis of ligand potency and efficacy at G protein-coupled receptors

(2010) Philip G. Strange   BRITISH JOURNAL OF PHARMACOLOGY

Label-free whole-cell assays: expanding the scope of GPCR screening

(2010) Clay W Scott et al.   DRUG DISCOVERY TODAY

Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

(2010) J. A. Hern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nanodisc: a novel tool for membrane protein studies

(2009) Jonas Borch et al.   BIOLOGICAL CHEMISTRY

Label-free fluorescent real-time monitoring of adenylyl cyclase

(2009) Hyun-Woo Rhee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Constitutive Dimerization of the G-Protein Coupled Receptor, Neurotensin Receptor 1, Reconstituted into Phospholipid Bilayers

(2009) Peter J. Harding et al.   BIOPHYSICAL JOURNAL

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Fine-tuning of GPCR activity by receptor-interacting proteins

(2009) Stefanie L. Ritter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nanodiscs for Immobilization of Lipid Bilayers and Membrane Receptors: Kinetic Analysis of Cholera Toxin Binding to a Glycolipid Receptor

(2008) Jonas Borch et al.   ANALYTICAL CHEMISTRY

Examining the Contributions of Lipid Shape and Headgroup Charge on Bilayer Behavior

(2008) Allison Dickey et al.   BIOPHYSICAL JOURNAL

G Protein β γ Subunits as Targets for Small Molecule Therapeutic Development

(2008) Alan Smrcka et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Rapid Incorporation of Functional Rhodopsin into Nanoscale Apolipoprotein Bound Bilayer (NABB) Particles

(2008) Sourabh Banerjee et al.   JOURNAL OF MOLECULAR BIOLOGY

Improved yield of a ligand-binding GPCR expressed in E. coli for structural studies

(2008) Helen Attrill et al.   PROTEIN EXPRESSION AND PURIFICATION