Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains

The identification of short linear motif-mediated interfaces within the human interactome

(2012) R. J. Weatheritt et al.   BIOINFORMATICS

Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition

(2011) Jose M. Martin-Garcia et al.   BIOCHEMICAL JOURNAL

Nef Surfaces: Where to Interfere with Function

(2011) Sebastian Lulf et al.   CURRENT HIV RESEARCH

Finding a better path to drug selectivity

(2011) Yuko Kawasaki et al.   DRUG DISCOVERY TODAY

Thermodynamics-based drug design: strategies for inhibiting protein–protein interactions

(2011) Arne Schön et al.   Future Medicinal Chemistry

Molecular Docking with Ligand Attached Water Molecules

(2011) Mette A. Lie et al.   Journal of Chemical Information and Modeling

Specific Oncogenic Activity of the Src-Family Tyrosine Kinase c-Yes in Colon Carcinoma Cells

(2011) Florence Sancier et al.   PLoS One

Evolving specificity from variability for protein interaction domains

(2011) Tomonori Kaneko et al.   TRENDS IN BIOCHEMICAL SCIENCES

MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains

(2010) Hugo YK Lam et al.   BMC BIOINFORMATICS

Some Binding-Related Drug Properties are Dependent on Thermodynamic Signature

(2010) Arne Schön et al.   Chemical Biology & Drug Design

The Role of Water Molecules in Computational Drug Design

(2010) Stephanie de Beer et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Ligand−Protein Cross-Docking with Water Molecules

(2010) Ramasamy Thilagavathi et al.   Journal of Chemical Information and Modeling

A survey of left-handed polyproline II helices

(2010) Benjamin J. Stapley et al.   PROTEIN SCIENCE

SH3 Domains of Grb2 Adaptor Bind to PXψPXR Motifs Within the Sos1 Nucleotide Exchange Factor in a Discriminate Manner

(2009) Caleb B. McDonald et al.   BIOCHEMISTRY

Recognition of lysine-rich peptide ligands by murine cortactin SH3 domain: CD, ITC, and NMR studies

(2009) Chiara Rubini et al.   BIOPOLYMERS

A Thermodynamic Approach to the Affinity Optimization of Drug Candidates

(2009) Ernesto Freire   Chemical Biology & Drug Design

Role of Interfacial Water Molecules in Proline-rich Ligand Recognition by the Src Homology 3 Domain of Abl

(2009) Andres Palencia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterizing the Role of Ensemble Modulation in Mutation-Induced Changes in Binding Affinity

(2009) Anthony Manson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Adding calorimetric data to decision making in lead discovery: a hot tip

(2009) John E. Ladbury et al.   NATURE REVIEWS DRUG DISCOVERY

ELM: the status of the 2010 eukaryotic linear motif resource

(2009) Cathryn M. Gould et al.   NUCLEIC ACIDS RESEARCH

Calorimetry and Thermodynamics in Drug Design

(2008) Jonathan B. Chaires   Annual Review of Biophysics

Do enthalpy and entropy distinguish first in class from best in class?

(2008) E FREIRE   DRUG DISCOVERY TODAY

The SH3 domain- a family of versatile peptide- and protein-recognition module

(2008) Tomonori Kaneko   Frontiers in Bioscience-Landmark

Ligand−Protein Docking with Water Molecules

(2008) Benjamin C. Roberts et al.   Journal of Chemical Information and Modeling

Structural Basis of PxxDY Motif Recognition in SH3 Binding

(2008) Olli Aitio et al.   JOURNAL OF MOLECULAR BIOLOGY

Thermodynamic consequences of disrupting a water-mediated hydrogen bond network in a protein:pheromone complex

(2004) Scott D. Sharrow et al.   PROTEIN SCIENCE