Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling

PI3K signalling: the path to discovery and understanding

(2012) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CDK1-mediated Phosphorylation of Abi1 Attenuates Bcr-Abl-induced F-actin Assembly and Tyrosine Phosphorylation of WAVE Complex during Mitosis

(2011) Chunmei Zhuang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration

(2011) Zhizhan Gu et al.   JOURNAL OF CELL BIOLOGY

PI3K p110β: More Tightly Controlled or Constitutively Active?

(2011) Peter K. Vogt   MOLECULAR CELL

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

(2011) Xuxiao Zhang et al.   MOLECULAR CELL

ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex

(2011) Michelle C. Mendoza et al.   MOLECULAR CELL

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

(2011) P. M. Dubielecka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

(2011) V. Koronakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Abl interactor 1 and its prognostic significance in breast cancer: a tissue-array-based investigation

(2010) Chunjie Wang et al.   BREAST CANCER RESEARCH AND TREATMENT

Integrity of SOS1/EPS8/ABI1 Tri-Complex Determines Ovarian Cancer Metastasis

(2010) H. Chen et al.   CANCER RESEARCH

Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells

(2010) Patrycja M. Dubielecka et al.   FEBS LETTERS

SCAR/WAVE is activated at mitosis and drives myosin-independent cytokinesis

(2010) J. S. King et al.   JOURNAL OF CELL SCIENCE

The PI3K Pathway As Drug Target in Human Cancer

(2010) Kevin D. Courtney et al.   JOURNAL OF CLINICAL ONCOLOGY

Structure and control of the actin regulatory WAVE complex

(2010) Zhucheng Chen et al.   NATURE

A nucleator arms race: cellular control of actin assembly

(2010) Kenneth G. Campellone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential Regulation of Macropinocytosis by Abi1/Hssh3bp1 Isoforms

(2010) Patrycja M. Dubielecka et al.   PLoS One

A biochemical mechanism for the oncogenic potential of the p110  catalytic subunit of phosphoinositide 3-kinase

(2010) H. A. Dbouk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the  4 integrin

(2010) C. Ring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer-derived mutations in the regulatory subunit p85  of phosphoinositide 3-kinase function through the catalytic subunit p110 

(2010) M. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyfip1 Is a Putative Invasion Suppressor in Epithelial Cancers

(2009) Jose M. Silva et al.   CELL

Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages

(2009) S. Yoshida et al.   JOURNAL OF CELL SCIENCE

Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma

(2009) Meihua Cui et al.   MEDICAL ONCOLOGY

Regulation of Cell-Cell Adhesion by Abi/Diaphanous Complexes

(2009) J. R. Ryu et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of the WAVE Complex by Coincident Signals Controls Actin Assembly

(2009) Andres M. Lebensohn et al.   MOLECULAR CELL

The WAVE regulatory complex is inhibited

(2009) Ayman M Ismail et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WAVE3 is associated with invasiveness in prostate cancer cells

(2009) Herman S. Fernando et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1

(2008) Xiaoling Xiong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Rho GTPases in cancer cell biology

(2008) Francisco M. Vega et al.   FEBS LETTERS

On the Rho'd: The regulation of membrane protrusions by Rho-GTPases

(2008) Markus Ladwein et al.   FEBS LETTERS

WAVE1 is Associated With Invasiveness and Growth of Prostate Cancer Cells

(2008) Herman S. Fernando et al.   JOURNAL OF UROLOGY