Synthetic Biology of secondary metabolite biosynthesis in actinomycetes: Engineering precursor supply as a way to optimize antibiotic production

Genome-scale metabolic representation of Amycolatopsis balhimycina

(2012) Wanwipa Vongsangnak et al.   BIOTECHNOLOGY AND BIOENGINEERING

Natural products from synthetic biology

(2011) Wayne Mitchell   CURRENT OPINION IN CHEMICAL BIOLOGY

Conjugal plasmid transfer inStreptomycesresembles bacterial chromosome segregation by FtsK/SpoIIIE

(2011) Jutta Vogelmann et al.   EMBO JOURNAL

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Glycopeptide biosynthesis in the context of basic cellular functions

(2010) Evi Stegmann et al.   CURRENT OPINION IN MICROBIOLOGY

Identification and functional characterization of phenylglycine biosynthetic genes involved in pristinamycin biosynthesis in Streptomyces pristinaespiralis

(2010) Yvonne J. Mast et al.   JOURNAL OF BIOTECHNOLOGY

Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster

(2010) Jette Thykaer et al.   METABOLIC ENGINEERING

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

(2010) Juan Pablo Gomez-Escribano et al.   Microbial Biotechnology

Characterization of the ‘pristinamycin supercluster’ of Streptomyces pristinaespiralis

(2010) Yvonne Mast et al.   Microbial Biotechnology

Systems Biology: The elements and principles of Life

(2009) Hans V. Westerhoff et al.   FEBS LETTERS

CLUSEAN: A computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters

(2009) T. Weber et al.   JOURNAL OF BIOTECHNOLOGY

Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks

(2009) Christina M. Agapakis et al.   Molecular BioSystems

Module Extension of a Non-Ribosomal Peptide Synthetase of the Glycopeptide Antibiotic Balhimycin Produced byAmycolatopsis balhimycina

(2008) Diane Butz et al.   CHEMBIOCHEM

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

(2008) Carlos Olano et al.   METABOLIC ENGINEERING