An autoregulatory feedback loop between Mdm2 and SHP that fine tunes Mdm2 and SHP stability

Regulation of miR-200c by nuclear receptors PPARα, LRH-1 and SHP

(2011) Yuxia Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mdm2 is a novel activator of ApoCIII promoter which is antagonized by p53 and SHP inhibition

(2011) Zhihong Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nuclear receptor SHP inhibition of Dnmt1 expression via ERRγ

(2011) Yuxia Zhang et al.   FEBS LETTERS

Diurnal Regulation of the Early Growth Response 1 (Egr-1) Protein Expression by Hepatocyte Nuclear Factor 4α (HNF4α) and Small Heterodimer Partner (SHP) Cross-talk in Liver Fibrosis

(2011) Yuxia Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of microRNA expression and function by nuclear receptor signaling

(2011) Zhihong Yang et al.   Cell and Bioscience

Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism

(2010) Jiansheng Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

(2010) J. J. Manfredi   GENES & DEVELOPMENT

Novel Polymorphisms of Nuclear Receptor SHP Associated with Functional and Structural Changes

(2010) Taofeng Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Pathway Involving Farnesoid X Receptor and Small Heterodimer Partner Positively Regulates Hepatic Sirtuin 1 Levels via MicroRNA-34a Inhibition

(2010) Jiyoung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Receptor SHP, a Death Receptor That Targets Mitochondria, Induces Apoptosis and Inhibits Tumor Growth

(2010) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Systems-level analysis of gene expression data revealed NR0B2/SHP as potential tumor suppressor in human liver cancer

(2010) Yun-Yong Park et al.   MOLECULES AND CELLS

The p53 orchestra: Mdm2 and Mdmx set the tone

(2010) Mark Wade et al.   TRENDS IN CELL BIOLOGY

Mdm2-mediated ubiquitylation: p53 and beyond

(2009) J-C Marine et al.   CELL DEATH AND DIFFERENTIATION

Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation

(2009) J. Miao et al.   GENES & DEVELOPMENT

MicroRNA-206 Targetsnotch3, Activates Apoptosis, and Inhibits Tumor Cell Migration and Focus Formation

(2009) Guisheng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Receptor SHP Activates miR-206 Expression via a Cascade Dual Inhibitory Mechanism

(2009) Guisheng Song et al.   PLoS One

A Conserved Gene Structure and Expression Regulation of miR-433 and miR-127 in Mammals

(2009) Guisheng Song et al.   PLoS One

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Epigenetic Inhibition of Nuclear Receptor Small Heterodimer Partner Is Associated With and Regulates Hepatocellular Carcinoma Growth

(2008) Nan He et al.   GASTROENTEROLOGY

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

(2008) T. Terzian et al.   GENES & DEVELOPMENT

Orphan receptor small heterodimer partner suppresses tumorigenesis by modulating cyclin D1 expression and cellular proliferation

(2008) Yuxia Zhang et al.   HEPATOLOGY

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

(2008) Yaara Ofir-Rosenfeld et al.   MOLECULAR CELL

p53 mRNA controls p53 activity by managing Mdm2 functions

(2008) Marco M. Candeias et al.   NATURE CELL BIOLOGY

Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRγ

(2008) Guisheng Song et al.   NUCLEIC ACIDS RESEARCH

MiR-433 and miR-127 Arise from Independent Overlapping Primary Transcripts Encoded by the miR-433-127 Locus

(2008) Guisheng Song et al.   PLoS One