The mode of α-synuclein binding to membranes depends on lipid composition and lipid to protein ratio

Specificity and Kinetics of α-Synuclein Binding to Model Membranes Determined with Fluorescent Excited State Intramolecular Proton Transfer (ESIPT) Probe

(2011) Volodymyr V. Shvadchak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein Populates Both Elongated and Broken Helix States on Small Unilamellar Vesicles

(2011) Sowmya Bekshe Lokappa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anisotropic Solvent Model of the Lipid Bilayer. 2. Energetics of Insertion of Small Molecules, Peptides, and Proteins in Membranes

(2011) Andrei L. Lomize et al.   Journal of Chemical Information and Modeling

Monitoring membrane binding and insertion of peptides by two-color fluorescent label

(2010) V.Y. Postupalenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The N-Terminus of the Intrinsically Disordered Protein α-Synuclein Triggers Membrane Binding and Helix Folding

(2010) Tim Bartels et al.   BIOPHYSICAL JOURNAL

Direct Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synuclein

(2010) Marta Robotta et al.   CHEMPHYSCHEM

Tryptophan Probes at the α-Synuclein and Membrane Interface

(2010) Candace M. Pfefferkorn et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Combinatorial NMR and EPR Approach for Evaluating the Structural Ensemble of Partially Folded Proteins

(2010) Jampani Nageswara Rao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorescent Ratiometric MFC Probe Sensitive to Early Stages of α-Synuclein Aggregation

(2010) Dmytro A. Yushchenko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

α-Synuclein Binds Large Unilamellar Vesicles as an Extended Helix†

(2009) Adam J. Trexler et al.   BIOCHEMISTRY

Monitoring Biophysical Properties of Lipid Membranes by Environment-Sensitive Fluorescent Probes

(2009) Alexander P. Demchenko et al.   BIOPHYSICAL JOURNAL

Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy

(2009) Christina R. Bodner et al.   JOURNAL OF MOLECULAR BIOLOGY

Tryptophan Fluorescence Reveals Structural Features of α-Synuclein Oligomers

(2009) B.D. van Rooijen et al.   JOURNAL OF MOLECULAR BIOLOGY

A Combined Pulse EPR and Monte Carlo Simulation Study Provides Molecular Insight on Peptide−Membrane Interactions

(2009) Michal Gordon-Grossman et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Sensing peptide–oligonucleotide interactions by a two-color fluorescence label: application to the HIV-1 nucleocapsid protein

(2009) Volodymyr V. Shvadchak et al.   NUCLEIC ACIDS RESEARCH

Spin-Label EPR on α-Synuclein Reveals Differences in the Membrane Binding Affinity of the Two Antiparallel Helices

(2008) Malte Drescher et al.   CHEMBIOCHEM

Structural insights on physiological functions and pathological effects of α-synuclein

(2008) Marco Bisaglia et al.   FASEB JOURNAL

Membrane-Bound α-Synuclein Forms an Extended Helix: Long-Distance Pulsed ESR Measurements Using Vesicles, Bicelles, and Rodlike Micelles

(2008) Elka R. Georgieva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of membrane-bound  -synuclein from site-directed spin labeling and computational refinement

(2008) C. C. Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA