Effector T cells in rheumatoid arthritis: Lessons from animal models

CD4+ T Cells Recognizing a Single Self-Peptide Expressed by APCs Induce Spontaneous Autoimmune Arthritis

(2014) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Delineating the Role of the HLA-DR4 "Shared Epitope" in Susceptibility versus Resistance to Develop Arthritis

(2014) V. Taneja et al.   JOURNAL OF IMMUNOLOGY

Development of Proteoglycan-Induced Arthritis Is Independent of IL-17

(2014) P. D. Doodes et al.   JOURNAL OF IMMUNOLOGY

Ameliorated course of glucose-6-phosphate isomerase (G6PI)-induced arthritis in IFN-γ receptor knockout mice exposes an arthritis-promoting role of IFN-γ

(2011) Oliver Frey et al.   JOURNAL OF AUTOIMMUNITY

SLAP Deficiency Enhances Number and Function of Regulatory T Cells Preventing Chronic Autoimmune Arthritis in SKG Mice

(2011) L. K. Peterson et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ Regulatory T Cells Control Humoral Autoimmunity by Suppressing the Development of Long-Lived Plasma Cells

(2011) E. Jang et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis

(2010) O. Frey et al.   ANNALS OF THE RHEUMATIC DISEASES

Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis

(2010) Bruno R. Raposo et al.   ARTHRITIS AND RHEUMATISM

Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis

(2010) Adriana M. C. Mus et al.   ARTHRITIS AND RHEUMATISM

Role of Th17 cells in human autoimmune arthritis

(2010) Jan Leipe et al.   ARTHRITIS AND RHEUMATISM

CD4+ T cells from collagen-induced arthritic mice are essential to transfer arthritis into severe combined immunodeficient mice

(2010) K. M. KADOWAKI et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Percutaneous exposure of adjuvant oil causes arthritis in DA rats

(2010) S. KLEINAU et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model

(2010) Sachi Tsunemi et al.   CLINICAL IMMUNOLOGY

Th17 cells can provide B cell help in autoantibody induced arthritis

(2010) Cynthia L. Hickman-Brecks et al.   JOURNAL OF AUTOIMMUNITY

Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function

(2010) S. Tanaka et al.   JOURNAL OF IMMUNOLOGY

Modulation of IL-17 and Foxp3 Expression in the Prevention of Autoimmune Arthritis in Mice

(2010) Joana Duarte et al.   PLoS One

The Therapeutic Effect of Vasoactive Intestinal Peptide on Experimental Arthritis is Associated with CD4+CD25+ T Regulatory Cells

(2010) G. Chen et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis

(2009) Gabriel Criado et al.   ARTHRITIS AND RHEUMATISM

Th17 and natural Treg cell population dynamics in systemic lupus erythematosus

(2009) Ji Yang et al.   ARTHRITIS AND RHEUMATISM

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

(2009) Yeonseok Chung et al.   IMMUNITY

CTLA4-Ig modifies dendritic cells from mice with collagen-induced arthritis to increase the CD4+CD25+Foxp3+ regulatory T cell population

(2009) Hyeok-Jae Ko et al.   JOURNAL OF AUTOIMMUNITY

IFN-  Regulates the Requirement for IL-17 in Proteoglycan-Induced Arthritis

(2009) P. D. Doodes et al.   JOURNAL OF IMMUNOLOGY

Genome-Wide Comparison between IL-17A- and IL-17F-Induced Effects in Human Rheumatoid Arthritis Synoviocytes

(2009) S. Zrioual et al.   JOURNAL OF IMMUNOLOGY

Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORγt in γδ T cells

(2009) Ferry Cornelissen et al.   ARTHRITIS RESEARCH & THERAPY

Heterogeneity of human effector CD4+ T cells

(2009) Francesco Annunziato et al.   ARTHRITIS RESEARCH & THERAPY

Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4

(2009) Sujata Sarkar et al.   ARTHRITIS RESEARCH & THERAPY

Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen-induced arthritis

(2008) Sharon Veenbergen et al.   ARTHRITIS AND RHEUMATISM

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

(2008) Minoru Fujimoto et al.   ARTHRITIS AND RHEUMATISM

Increased number and function of FoxP3 regulatory T cells during experimental arthritis

(2008) Kristen Monte et al.   ARTHRITIS AND RHEUMATISM

Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis

(2008) Paul J. Egan et al.   ARTHRITIS AND RHEUMATISM

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Inhibitory CD8+ T cells in autoimmune disease

(2008) Masakatsu Suzuki et al.   HUMAN IMMUNOLOGY

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

(2008) Jonathan A. Hill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Construction and characterization of a novel DNA vaccine that is potent antigen-specific tolerizing therapy for experimental arthritis by increasing CD4+CD25+Treg cells and inducing Th1 to Th2 shift in both cells and cytokines

(2008) Song Xinqiang et al.   VACCINE

High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

(2008) Ranjeny Thomas et al.   ARTHRITIS RESEARCH & THERAPY