Uncoupling protein UCP2: When mitochondrial activity meets immunity

UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing

(2009) Frédéric Bouillaud   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Persistent Oxidative Stress Due to Absence of Uncoupling Protein 2 Associated with Impaired Pancreatic β-Cell Function

(2009) Jingbo Pi et al.   ENDOCRINOLOGY

Association of UCP2 −866 G/A polymorphism with chronic inflammatory diseases

(2009) X Yu et al.   GENES AND IMMUNITY

UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?

(2009) Claire Pecqueur et al.   IUBMB LIFE

Mitochondrial Uncoupling Protein 2 Inhibits Mast Cell Activation and Reduces Histamine Content

(2009) M. Tagen et al.   JOURNAL OF IMMUNOLOGY

Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2

(2009) Yanlin Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Association of Common Variants of UCP2 Gene With Low-Grade Inflammation in Swedish Children and Adolescents; The European Youth Heart Study

(2009) Idoia Labayen et al.   PEDIATRIC RESEARCH

Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice

(2008) Fatiha Moukdar et al.   JOURNAL OF LIPID RESEARCH

Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)γ co-activator-1β is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells

(2008) Hannes Oberkofler et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

(2008) Zane B. Andrews et al.   NATURE

Modified glutamine catabolism in macrophages of Ucp2 knock-out mice

(2007) Tobias Nübel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2

(2007) Denis Selimovic et al.   CELLULAR SIGNALLING

Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization

(2007) Claire Pecqueur et al.   FASEB JOURNAL