Lysosomal degradation of membrane lipids

Lysosomal storage diseases as disorders of autophagy

(2014) Carmine Settembre et al.   Autophagy

Neurodegenerative lysosomal disorders: A continuum from development to late age

(2014) Ralph A. Nixon et al.   Autophagy

GLUT8, the enigmatic intracellular hexose transporter

(2009) Stefan Schmidt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Niemann–Pick C2 (NPC2) and intracellular cholesterol trafficking

(2009) Judith Storch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Delivery of endocytosed membrane proteins to the lysosome

(2009) Paul R. Pryor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ligand Extraction Properties of the GM2 Activator Protein and Its Interactions with Lipid Vesicles

(2009) Yong Ran et al.   BIOPHYSICAL JOURNAL

Bis(monoacylglycero)phosphate Forms Stable Small Lamellar Vesicle Structures: Insights into Vesicular Body Formation in Endosomes

(2009) Thomas E. Frederick et al.   BIOPHYSICAL JOURNAL

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

(2009) Hyock Joo Kwon et al.   CELL

Membrane Protein Targeting to the MVB/Lysosome

(2009) Brian A. Davies et al.   CHEMICAL REVIEWS

Endosomal processing for antigen presentation mediated by CD1 and Class I major histocompatibility complex: roads to display or destruction

(2009) Marianne Boes et al.   IMMUNOLOGY

Cholesterol-rich Fluid Membranes Solubilize Ceramide Domains

(2009) Bruno M. Castro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogenic cascades in lysosomal disease—Why so complex?

(2009) S. U. Walkley   JOURNAL OF INHERITED METABOLIC DISEASE

The role of negatively charged lipids in lysosomal phospholipase A2 function

(2009) Akira Abe et al.   JOURNAL OF LIPID RESEARCH

Immunologic Glycosphingolipidomics and NKT Cell Development in Mouse Thymus

(2009) Yunsen Li et al.   JOURNAL OF PROTEOME RESEARCH

New functions of cholesterol binding proteins

(2009) Jun-Ping Liu   MOLECULAR AND CELLULAR ENDOCRINOLOGY

All-you-can-eat: autophagy in neurodegeneration and neuroprotection

(2009) Philipp A Jaeger et al.   Molecular Neurodegeneration

Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism

(2009) Frank Rutsch et al.   NATURE GENETICS

New roles for endosomes: from vesicular carriers to multi-purpose platforms

(2009) Gwyn W. Gould et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosomal Storage Disorders in the Newborn

(2009) O. Staretz-Chacham et al.   PEDIATRICS

Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

(2009) B. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of the human ceramide activator protein saposin D

(2008) Konstantin Popovic et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Enhancing Immunity Through Autophagy

(2008) Christian Münz   Annual Review of Immunology

Regulation of Sterol Transport between Membranes and NPC2†

(2008) Zhi Xu et al.   BIOCHEMISTRY

Glycolipid transfer proteins and membrane interaction

(2008) Peter Mattjus   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lysosomes and oxidative stress in aging and apoptosis

(2008) Tino Kurz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Functions of sphingolipid metabolism in mammals — Lessons from genetic defects

(2008) Frédérique Sabourdy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The yeast lysosome-like vacuole: Endpoint and crossroads

(2008) Sheena Claire Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Proteomics of the lysosome

(2008) Torben Lübke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann–Pick C1 disease — Lysosomal storage disorders caused by defects of non-lysosomal proteins

(2008) Thomas Dierks et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular and cellular basis of lysosomal transmembrane protein dysfunction

(2008) Raquel Ruivo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lysosomal involvement in cell death and cancer

(2008) Thomas Kirkegaard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Sorting of lysosomal proteins

(2008) Thomas Braulke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Secondary lipid accumulation in lysosomal disease

(2008) Steven U. Walkley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Principles of lysosomal membrane degradation

(2008) Heike Schulze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lysosomal disorders: From storage to cellular damage

(2008) Andrea Ballabio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Treating lysosomal storage disorders: Current practice and future prospects

(2008) Frances M. Platt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Sphingolipid management by an orchestra of lipid transfer proteins

(2008) Sylvia Neumann et al.   BIOLOGICAL CHEMISTRY

Phospholipase A2 Biochemistry

(2008) John E. Burke et al.   CARDIOVASCULAR DRUGS AND THERAPY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Niemann-Pick C1 protein transports copper to the secretory compartment from late endosomes where ATP7B resides

(2008) Chikatoshi Yanagimoto et al.   EXPERIMENTAL CELL RESEARCH

Molecular assemblies and membrane domains in multivesicular endosome dynamics

(2008) Thomas Falguières et al.   EXPERIMENTAL CELL RESEARCH

Imaging and imagination: understanding the endo-lysosomal system

(2008) Eline Meel et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Lysosomes in iron metabolism, ageing and apoptosis

(2008) Tino Kurz et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice

(2008) Y. Sun et al.   HUMAN MOLECULAR GENETICS

ADrosophilaProtein Family Implicated in Pheromone Perception Is Related to Tay-Sachs GM2-Activator Protein

(2008) Elena Starostina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels

(2008) Julien Chevallier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coenzyme Q10-Binding/Transfer Protein Saposin B also Binds γ-Tocopherol

(2008) GuangZhi Jin et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Saposin B Is a Human Coenzyme Q10-Binding/Transfer Protein

(2008) GuangZhi Jin et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Molecular physiology and pathophysiology of lysosomal membrane transporters

(2008) C. Sagné et al.   JOURNAL OF INHERITED METABOLIC DISEASE

The integral membrane of lysosomes: Its proteins and their roles in disease

(2008) John W. Callahan et al.   Journal of Proteomics

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

(2008) Emyr Lloyd-Evans et al.   NATURE MEDICINE

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

Crystal Structures of Human Saposins C and D: Implications for Lipid Recognition and Membrane Interactions

(2008) Maxim Rossmann et al.   STRUCTURE

Sphingolipids and membrane biology as determined from genetic models

(2007) Raghavendra Pralhada Rao et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Cytosol to Lysosome Transport of Intracellular Antigens During Immune Surveillance

(2007) Victoria L. Crotzer et al.   TRAFFIC