Leucine-rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase-3β

The genetics and neuropathology of Parkinson’s disease

(2012) Henry Houlden et al.   ACTA NEUROPATHOLOGICA

Allergy influences the inflammatory status of the brain and enhances tau-phosphorylation

(2012) Heela Sarlus et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

LRRK2 I2020T mutation is associated with tau pathology

(2012) Sachiko Ujiie et al.   PARKINSONISM & RELATED DISORDERS

LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth

(2012) Fumitaka Kawakami et al.   PLoS One

Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β

(2011) Fumitaka Kawakami et al.   FEBS Journal

Atypical tauopathy in a patient with LRRK2-G2019S mutation and tremor-dominant Parkinsonism

(2011) C. Ruffmann et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

LRRK2 G2019S Mutation Induces Dendrite Degeneration through Mislocalization and Phosphorylation of Tau by Recruiting Autoactivated GSK3 

(2010) C.-H. Lin et al.   JOURNAL OF NEUROSCIENCE

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

(2010) H.L. Melrose et al.   NEUROBIOLOGY OF DISEASE

I2020T leucine-rich repeat kinase 2, the causative mutant molecule of familial Parkinson’s disease, has a higher intracellular degradation rate than the wild-type molecule

(2009) Etsuro Ohta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?

(2009) Frank Gillardon   JOURNAL OF NEUROCHEMISTRY

Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

(2009) Yanping Li et al.   NATURE NEUROSCIENCE

Inflammation induces tau pathology in inclusion body myositis model via glycogen synthase kinase-3β

(2008) Masashi Kitazawa et al.   ANNALS OF NEUROLOGY