Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1

Decorin

(2012) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation

(2012) Kristin Moreth et al.   CELL CYCLE

Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation

(2012) Liliana Schaefer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Glycosaminoglycans: from “cellular glue” to novel therapeutical agents

(2012) Nikos K Karamanos et al.   CURRENT OPINION IN PHARMACOLOGY

The Biology of Small Leucine-rich Proteoglycans in Bone Pathophysiology

(2012) Dragana Nikitovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endorepellin Affects Angiogenesis by Antagonizing Diverse Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)-evoked Signaling Pathways

(2012) Atul Goyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombospondins in physiology and disease: New tricks for old dogs

(2012) Joanne E. Murphy-Ullrich et al.   MATRIX BIOLOGY

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity

(2012) Alessandra Lo Cicero et al.   MATRIX BIOLOGY

The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47

(2012) David D. Roberts et al.   MATRIX BIOLOGY

Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms

(2012) Mariya T. Sweetwyne et al.   MATRIX BIOLOGY

Thrombospondins as key regulators of synaptogenesis in the central nervous system

(2012) W. Christopher Risher et al.   MATRIX BIOLOGY

Adhesion-modulating/matricellular ECM protein families: A structural, functional and evolutionary appraisal

(2012) Deane F. Mosher et al.   MATRIX BIOLOGY

Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model

(2012) Simone Buraschi et al.   PLoS One

Recent advances on the role of tumor exosomes in immunosuppression and disease progression

(2012) Paola Filipazzi et al.   SEMINARS IN CANCER BIOLOGY

The Genomic and Proteomic Content of Cancer Cell-Derived Exosomes

(2012) Meredith C. Henderson et al.   Frontiers in Oncology

Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice

(2011) X. Bi et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

MicroRNA-148a Suppresses Tumor Cell Invasion and Metastasis by Downregulating ROCK1 in Gastric Cancer

(2011) B. Zheng et al.   CLINICAL CANCER RESEARCH

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

(2011) Yasuyuki Hosono et al.   EMBO JOURNAL

Endorepellin, the Angiostatic Module of Perlecan, Interacts with Both the α2β1 Integrin and Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)

(2011) Atul Goyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Antagonizes IGF Receptor I (IGF-IR) Function by Interfering with IGF-IR Activity and Attenuating Downstream Signaling

(2011) Renato V. Iozzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Antagonizes the Angiogenic Network

(2011) Thomas Neill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role for Decorin in Delayed-Type Hypersensitivity

(2011) D. G. Seidler et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

(2011) C. C.-L. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21

(2011) R. Merline et al.   Science Signaling

The Thrombospondins

(2011) J. C. Adams et al.   Cold Spring Harbor Perspectives in Biology

Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting

(2010) Achilleas D. Theocharis et al.   FEBS Journal

Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans

(2010) Renato V. Iozzo et al.   FEBS Journal

Decorin Antagonizes Met Receptor Activity and Down-regulates β-Catenin and Myc Levels

(2010) Simone Buraschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteoglycans in cancer biology, tumour microenvironment and angiogenesis

(2010) Renato V. Iozzo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The role of small leucine-rich proteoglycans in collagen fibrillogenesis

(2010) Sebastian Kalamajski et al.   MATRIX BIOLOGY

p27kip1 Controls Cell Morphology and Motility by Regulating Microtubule-Dependent Lipid Raft Recycling

(2010) B. Belletti et al.   MOLECULAR AND CELLULAR BIOLOGY

Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level

(2009) Xuefeng Zhang et al.   FASEB JOURNAL

Targeted Disruption of ROCK1 Causes Insulin Resistancein Vivo

(2009) Dae Ho Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin is a novel antagonistic ligand of the Met receptor

(2009) Silvia Goldoni et al.   JOURNAL OF CELL BIOLOGY

Basement membrane proteoglycans: Modulators Par Excellence of cancer growth and angiogenesis

(2009) Renato V. Iozzo et al.   MOLECULES AND CELLS

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

The role of thrombospondins in wound healing, ischemia, and the foreign body reaction

(2009) Themis R. Kyriakides et al.   Journal of Cell Communication and Signaling

An Antimetastatic Role for Decorin in Breast Cancer

(2008) Silvia Goldoni et al.   AMERICAN JOURNAL OF PATHOLOGY

Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation

(2008) X. Bi et al.   CARCINOGENESIS

Thrombospondins: from structure to therapeutics

(2008) S. Kazerounian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs

(2008) Silvia Goldoni et al.   INTERNATIONAL JOURNAL OF CANCER

Biological Functions of the Small Leucine-rich Proteoglycans: From Genetics to Signal Transduction

(2008) Liliana Schaefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY