The expanding roles of 1-methyl-tryptophan (1-MT): in addition to inhibiting kynurenine production, 1-MT activates the synthesis of melatonin in skin cells

From chemotherapy to targeted treatment

(2012) R. Dummer et al.   ANNALS OF ONCOLOGY

New therapies in the treatment of melanoma

(2012) Diwakar Davar et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Immunoprotective Role of Indoleamine 2,3-Dioxygenase in Engraftment of Allogenic Skin Substitute in Wound Healing

(2012) Mohammad Ali Bahar et al.   Journal of Burn Care & Research

Melatonin membrane receptors in peripheral tissues: Distribution and functions

(2012) Radomir M. Slominski et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death

(2012) Carla A. Brohem et al.   Pigment Cell & Melanoma Research

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

(2012) L. Pilotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spontaneous Cytotoxic T-Cell Reactivity against Indoleamine 2,3-Dioxygenase-2

(2011) R. B. Sorensen et al.   CANCER RESEARCH

Expression of indoleamine 2,3-dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival

(2011) Jonathan R. Brody et al.   CELL CYCLE

Basic Mechanisms Involved in the Anti-Cancer Effects of Melatonin

(2011) M. D. Mediavilla et al.   CURRENT MEDICINAL CHEMISTRY

Indoleamine 2,3-dioxygenase, a new prognostic marker in sentinel lymph nodes of melanoma patients

(2011) Reinhart Speeckaert et al.   EUROPEAN JOURNAL OF CANCER

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido

(2011) Vinod P Balachandran et al.   NATURE MEDICINE

The Indoleamine-2,3-Dioxygenase (IDO) Inhibitor 1-Methyl-D-tryptophan Upregulates IDO1 in Human Cancer Cells

(2011) Christiane A. Opitz et al.   PLoS One

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional and phenotypic effects of AhR activation in inflammatory dendritic cells

(2010) Jaishree Bankoti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells

(2009) Damià Tormo et al.   CANCER CELL

Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase–Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer

(2009) Feng Qian et al.   CANCER RESEARCH

Melatonin in the skin: synthesis, metabolism and functions

(2008) Andrzej Slominski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM